| Literature DB >> 33371901 |
Ivana Celardo1, Luigia Pace2, Loredana Cifaldi3,4, Carlo Gaudio1, Vincenzo Barnaba5.
Abstract
Knowing the "point of view" of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host/pathogen interactions dictating protective immune response or immunopathology, addressing the role of immunity or immunopathology in influencing the clinical infection outcome, and debate the potential immunoprophylactic and immunotherapy strategies required to fight the virus infection.Entities:
Keywords: COVID-19; Coronavirus; Monoclonal antibodies; SARS-CoV-2; Vaccine
Mesh:
Substances:
Year: 2020 PMID: 33371901 PMCID: PMC7769684 DOI: 10.1186/s13062-020-00283-2
Source DB: PubMed Journal: Biol Direct ISSN: 1745-6150 Impact factor: 4.540