| Literature DB >> 32433943 |
Abstract
Exposure to chronic infection or malignant tumors triggers the differentiation of functionally impaired, so-called exhausted T cells. In this issue of Immunity, Beltra et al. reveal a multi-step developmental process that defines how T cells transition from proliferating progenitors into terminally differentiated exhausted T cells.Entities:
Year: 2020 PMID: 32433943 DOI: 10.1016/j.immuni.2020.04.019
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745