Literature DB >> 333549

Participation of C3 in intracellular killing of Candida albicans.

M Yamamura, H Valdimarsson.   

Abstract

Using new objective methods for measuring, independently, phagcytosis and killing, it was demonstrated that Candida albicans opsonized by C3-deficient serum was ingested by not killed in vitro by human polymorphonuclear leukocytes. Killing could be induced by adding purified C3 to the C3-deficient serum. It is concluded that C3 participates directely in the intracellular process leading to phagocytic killing of C. albicans.

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Year:  1977        PMID: 333549     DOI: 10.1111/j.1365-3083.1977.tb02137.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN: 0300-9475            Impact factor:   3.487


  13 in total

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Review 7.  An overview of macrophage-fungal interactions.

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Review 8.  Production and function of cytokines in natural and acquired immunity to Candida albicans infection.

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9.  Effect of mouse phagocytes on Candida albicans in in vivo chambers.

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