Literature DB >> 33334110

Photoredox Catalysis Enables Decarboxylative Cyclization with Hypervalent Iodine(III) Reagents: Access to 2,5-Disubstituted 1,3,4-Oxadiazoles.

Jian Li1, Xue-Chen Lu1, Yue Xu1, Jin-Xia Wen1, Guo-Quan Hou1, Li Liu1.   

Abstract

A novel approach to 2,5-disubstituted 1,3,4-oxadiazoles derivatives via a decarboxylative cyclization reaction by photoredox catalysis between commercially available α-oxocarboxylic acids and hypervalent iodine(III) reagent is described. This powerful transformation involves the coupling reaction between two different kinds of radical species and the formation of C-N and C-O bonds.

Entities:  

Year:  2020        PMID： 33334110     DOI： 10.1021/acs.orglett.0c03663

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Oxadiazol-based mTOR inhibitors with potent antiproliferative activities: synthetic and computational modeling.

Authors:  Mohammad A Khanfar
Journal:  Mol Divers       Date:  2022-01-05       Impact factor: 2.943

2.  Copper-Catalyzed One-Pot Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles from Arylacetic Acids and Hydrazides via Dual Oxidation.

Authors:  Chinnari Lekkala; Varaprasad Bodala; Kumari Yettula; Bharat Kumar Karasala; Rajitha Lakshmi Podugu; Siddaiah Vidavalur
Journal:  ACS Omega       Date:  2022-07-27

3.  Synthesis of 2-Imino-1,3,4-oxadiazolines from Acylhydrazides and Isothiocyanates via Aerobic Oxidation and a DMAP-Mediated Annulation Sequence.

Authors:  Jae Hyeok Lim; Sang Eun Baek; Bapurao Sudam Lad; Jinho Kim
Journal:  ACS Omega       Date:  2022-08-01

4.  Catalytic Synthesis of Cyclopropenium Cations with Rh-Carbynoids.

Authors:  Hang-Fei Tu; Aliénor Jeandin; Marcos G Suero
Journal:  J Am Chem Soc       Date:  2022-09-08       Impact factor: 16.383
  4 in total

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