Clayton Hamilton1, Janice Taylor1, Scott Mambourg1. 1. is an Informatics Pharmacist at the George E. Wahlen Medical Center in Salt Lake City, Utah. is the Veterans Integrated Service Network (VISN) 21 Pharmacy Benefits Management office Program and Data Manager, and is the VISN 21 Pharmacy Executive, both in Reno, Nevada.
Abstract
PURPOSE: This retrospective chart review is an evaluation of patient and health care provider adherence to a metabolic monitoring protocol as well as progression to type 2 diabetes mellitus (T2DM) in the first year after atypical antipsychotic initiation. METHODS: Patient (N = 1,651) data from February 2014 to February 2019 were collected from the US Department of Veterans Affairs (VA) Corporate Data Warehouse for 8 VA medical centers within Veterans Integrated Service Network (VISN) 21. Collected data included patient demographic, laboratory results, and medication history. RESULTS: In the final cohort, 6% of patients were found to have progressed to T2DM. Adherence to appropriate metabolic monitoring was found to be overall suboptimal. CONCLUSIONS: The findings of this project demonstrate that patients in VISN 21 who were previously antipsychotic-naïve and nondiabetic may be at increased risk of progression to T2DM when compared with the general population. To effectively manage patient risk, health care providers and patients should improve adherence to metabolic monitoring.
PURPOSE: This retrospective chart review is an evaluation of patient and health care provider adherence to a metabolic monitoring protocol as well as progression to type 2 diabetes mellitus (T2DM) in the first year after atypical antipsychotic initiation. METHODS: Patient (N = 1,651) data from February 2014 to February 2019 were collected from the US Department of Veterans Affairs (VA) Corporate Data Warehouse for 8 VA medical centers within Veterans Integrated Service Network (VISN) 21. Collected data included patient demographic, laboratory results, and medication history. RESULTS: In the final cohort, 6% of patients were found to have progressed to T2DM. Adherence to appropriate metabolic monitoring was found to be overall suboptimal. CONCLUSIONS: The findings of this project demonstrate that patients in VISN 21 who were previously antipsychotic-naïve and nondiabetic may be at increased risk of progression to T2DM when compared with the general population. To effectively manage patient risk, health care providers and patients should improve adherence to metabolic monitoring.
Authors: Anto P Rajkumar; Henriette Thisted Horsdal; Theresa Wimberley; Dan Cohen; Ole Mors; Anders D Børglum; Christiane Gasse Journal: Am J Psychiatry Date: 2017-01-20 Impact factor: 18.112
Authors: Donald C Goff; Lisa M Sullivan; Joseph P McEvoy; Jonathan M Meyer; Henry A Nasrallah; Gail L Daumit; Steven Lamberti; Ralph B D'Agostino; Thomas S Stroup; Sonia Davis; Jeffrey A Lieberman Journal: Schizophr Res Date: 2005-09-28 Impact factor: 4.939
Authors: Elaine H Morrato; Benjamin Druss; Daniel M Hartung; Robert J Valuck; Richard Allen; Elizabeth Campagna; John W Newcomer Journal: Arch Gen Psychiatry Date: 2010-01
Authors: Dinesh Mittal; Chenghui Li; James Silas Williams; Kristen Viverito; Reid D Landes; Richard R Owen Journal: Psychiatr Serv Date: 2013-01 Impact factor: 3.084