Literature DB >> 33328654

Controlling and enhancing CRISPR systems.

Haridha Shivram1,2, Brady F Cress1,2, Gavin J Knott1,2,3, Jennifer A Doudna4,5,6,7,8,9,10.   

Abstract

Many bacterial and archaeal organisms use clustered regularly interspaced short palindromic repeats-CRISPR associated (CRISPR-Cas) systems to defend themselves from mobile genetic elements. These CRISPR-Cas systems are classified into six types based on their composition and mechanism. CRISPR-Cas enzymes are widely used for genome editing and offer immense therapeutic opportunity to treat genetic diseases. To realize their full potential, it is important to control the timing, duration, efficiency and specificity of CRISPR-Cas enzyme activities. In this Review we discuss the mechanisms of natural CRISPR-Cas regulatory biomolecules and engineering strategies that enhance or inhibit CRISPR-Cas immunity by altering enzyme function. We also discuss the potential applications of these CRISPR regulators and highlight unanswered questions about their evolution and purpose in nature.

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Year:  2020        PMID： 33328654      PMCID： PMC8101458          DOI： 10.1038/s41589-020-00700-7

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


  98 in total

1.  Identification of genes that are associated with DNA repeats in prokaryotes.

Authors:  Ruud Jansen; Jan D A van Embden; Wim Gaastra; Leo M Schouls
Journal:  Mol Microbiol       Date:  2002-03       Impact factor: 3.501

2.  Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements.

Authors:  Francisco J M Mojica; César Díez-Villaseñor; Jesús García-Martínez; Elena Soria
Journal:  J Mol Evol       Date:  2005-02       Impact factor: 2.395

3.  H-NS-mediated repression of CRISPR-based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO.

Authors:  Edze R Westra; Umit Pul; Nadja Heidrich; Matthijs M Jore; Magnus Lundgren; Thomas Stratmann; Reinhild Wurm; Amanda Raine; Melina Mescher; Luc Van Heereveld; Marieke Mastop; E Gerhart H Wagner; Karin Schnetz; John Van Der Oost; Rolf Wagner; Stan J J Brouns
Journal:  Mol Microbiol       Date:  2010-08-18       Impact factor: 3.501

4.  Envelope stress is a trigger of CRISPR RNA-mediated DNA silencing in Escherichia coli.

Authors:  Ritsdeliz Perez-Rodriguez; Charles Haitjema; Qingqiu Huang; Ki Hyun Nam; Sarah Bernardis; Ailong Ke; Matthew P DeLisa
Journal:  Mol Microbiol       Date:  2010-12-13       Impact factor: 3.501

5.  The CRISPR/Cas immune system is an operon regulated by LeuO, H-NS, and leucine-responsive regulatory protein in Salmonella enterica serovar Typhi.

Authors:  L Medina-Aparicio; J E Rebollar-Flores; A L Gallego-Hernández; A Vázquez; L Olvera; R M Gutiérrez-Ríos; E Calva; I Hernández-Lucas
Journal:  J Bacteriol       Date:  2011-03-11       Impact factor: 3.490

Review 6.  Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.

Authors:  Kira S Makarova; Yuri I Wolf; Jaime Iranzo; Sergey A Shmakov; Omer S Alkhnbashi; Stan J J Brouns; Emmanuelle Charpentier; David Cheng; Daniel H Haft; Philippe Horvath; Sylvain Moineau; Francisco J M Mojica; David Scott; Shiraz A Shah; Virginijus Siksnys; Michael P Terns; Česlovas Venclovas; Malcolm F White; Alexander F Yakunin; Winston Yan; Feng Zhang; Roger A Garrett; Rolf Backofen; John van der Oost; Rodolphe Barrangou; Eugene V Koonin
Journal:  Nat Rev Microbiol       Date:  2019-12-19       Impact factor: 60.633

7.  Costs of CRISPR-Cas-mediated resistance in Streptococcus thermophilus.

Authors:  Pedro F Vale; Guillaume Lafforgue; Francois Gatchitch; Rozenn Gardan; Sylvain Moineau; Sylvain Gandon
Journal:  Proc Biol Sci       Date:  2015-08-07       Impact factor: 5.349

8.  Regulation of the Type I-F CRISPR-Cas system by CRP-cAMP and GalM controls spacer acquisition and interference.

Authors:  Adrian G Patterson; James T Chang; Corinda Taylor; Peter C Fineran
Journal:  Nucleic Acids Res       Date:  2015-05-24       Impact factor: 16.971

9.  Coupling transcriptional activation of CRISPR-Cas system and DNA repair genes by Csa3a in Sulfolobus islandicus.

Authors:  Tao Liu; Zhenzhen Liu; Qing Ye; Saifu Pan; Xiaodi Wang; Yingjun Li; Wenfang Peng; Yunxiang Liang; Qunxin She; Nan Peng
Journal:  Nucleic Acids Res       Date:  2017-09-06       Impact factor: 16.971

10.  CRISPR-Cas type I-A Cascade complex couples viral infection surveillance to host transcriptional regulation in the dependence of Csa3b.

Authors:  Fei He; Gisle Vestergaard; Wenfang Peng; Qunxin She; Xu Peng
Journal:  Nucleic Acids Res       Date:  2017-02-28       Impact factor: 16.971
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  20 in total

Review 1.  Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins.

Authors:  Ning Jia; Dinshaw J Patel
Journal:  Nat Rev Mol Cell Biol       Date:  2021-06-04       Impact factor: 94.444

Review 2.  RNA-targeting CRISPR-Cas systems.

Authors:  Sam P B van Beljouw; Jasper Sanders; Alicia Rodríguez-Molina; Stan J J Brouns
Journal:  Nat Rev Microbiol       Date:  2022-09-28       Impact factor: 78.297

3.  VEGF-A controls the expression of its regulator of angiogenic functions, dopamine D2 receptor, on endothelial cells.

Authors:  Chandrani Sarkar; Debanjan Chakroborty; Sandeep Goswami; Hao Fan; Xiaokui Mo; Sujit Basu
Journal:  J Cell Sci       Date:  2022-05-31       Impact factor: 5.235

Review 4.  CRISPR/Cas9 System: A Potential Tool for Genetic Improvement in Floricultural Crops.

Authors:  Ujjwal Sirohi; Mukesh Kumar; Vinukonda Rakesh Sharma; Sachin Teotia; Deepali Singh; Veena Chaudhary; Manoj Kumar Yadav
Journal:  Mol Biotechnol       Date:  2022-06-25       Impact factor: 2.860

Review 5.  Tips, Tricks, and Potential Pitfalls of CRISPR Genome Editing in Saccharomyces cerevisiae.

Authors:  Jacob S Antony; John M Hinz; John J Wyrick
Journal:  Front Bioeng Biotechnol       Date:  2022-05-30

Review 6.  Genetically modified crop regulations: scope and opportunity using the CRISPR-Cas9 genome editing approach.

Authors:  Shweta Gupta; Adarsh Kumar; Rupali Patel; Vinay Kumar
Journal:  Mol Biol Rep       Date:  2021-06-10       Impact factor: 2.316

Review 7.  CRISPR-based genome editing through the lens of DNA repair.

Authors:  Tarun S Nambiar; Lou Baudrier; Pierre Billon; Alberto Ciccia
Journal:  Mol Cell       Date:  2022-01-20       Impact factor: 17.970

Review 8.  Targeting Cancer with CRISPR/Cas9-Based Therapy.

Authors:  Katarzyna Balon; Adam Sheriff; Joanna Jacków; Łukasz Łaczmański
Journal:  Int J Mol Sci       Date:  2022-01-05       Impact factor: 5.923

Review 9.  The Ultimate (Mis)match: When DNA Meets RNA.

Authors:  Benoit Palancade; Rodney Rothstein
Journal:  Cells       Date:  2021-06-08       Impact factor: 7.666

10.  Darwinian genomics and diversity in the tree of life.

Authors:  Taylorlyn Stephan; Shawn M Burgess; Hans Cheng; Charles G Danko; Clare A Gill; Erich D Jarvis; Klaus-Peter Koepfli; James E Koltes; Eric Lyons; Pamela Ronald; Oliver A Ryder; Lynn M Schriml; Pamela Soltis; Sue VandeWoude; Huaijun Zhou; Elaine A Ostrander; Elinor K Karlsson
Journal:  Proc Natl Acad Sci U S A       Date:  2022-01-25       Impact factor: 11.205
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