| Literature DB >> 33322162 |
Mohammed Sikander1,2, Shabnam Malik1,2, Anyssa Rodriguez1,2, Murali M Yallapu1,2, Acharan S Narula3, Sanjaya K Satapathy4, Vijian Dhevan5, Subhash C Chauhan1,2, Meena Jaggi1,2.
Abstract
COVID-19 is known as one of the deadliest pandemics of the century. The rapid spread of this deadly virus at incredible speed has stunned the planet and poses a challenge to global scientific and medical communities. Patients with COVID-19 are at an increased risk of co-morbidities associated with liver dysfunction and injury. Moreover, hepatotoxicity induced by antiviral therapy is gaining importance and is an area of great concern. Currently, alternatives therapies are being sought to mitigate hepatic damage, and there has been growing interest in the research on bioactive phytochemical agents (nutraceuticals) due to their versatility in health benefits reported in various epidemiological studies. Therefore, this review provides information and summarizes the juncture of antiviral, immunomodulatory, and hepatoprotective nutraceuticals that can be useful during the management of COVID-19.Entities:
Keywords: ACE2; COVID-19; SARS-CoV-2; coronavirus; hepatic dysfunctions; hepatoprotective agents; nutraceuticals
Mesh：
Substances：
Year: 2020 PMID： 33322162 PMCID： PMC7764432 DOI： 10.3390/molecules25245905
Source DB: PubMed Journal: Molecules ISSN： 1420-3049 Impact factor: 4.411