Literature DB >> 33317668

Uncovering reasons for treatment initiation delays among children with TB in Lima, Peru.

J Coit1, M Wong2, J T Galea3, M Mendoza2, H Marin2, M Tovar2, S S Chiang4, L Lecca2, M F Franke1.   

Abstract

BACKGROUND: Timely diagnosis and treatment of pediatric tuberculosis (TB) is critical to reducing mortality but remains challenging in the absence of adequate diagnostic tools. Even once a TB diagnosis is made, delays in treatment initiation are common, but for reasons that are not well understood.
METHODS: To examine reasons for delay post-diagnosis, we conducted semi-structured interviews with Ministry of Health (MoH) physicians and field workers affiliated with a pediatric TB diagnostic study, and caregivers of children aged 0-14 years who were diagnosed with pulmonary TB in Lima, Peru. Interviews were analyzed using systematic comparative and descriptive content analysis.
RESULTS: We interviewed five physicians, five field workers and 26 caregivers with children who initiated TB treatment < 7 days after diagnosis (n = 15) or who experienced a delay of ≥7 days (n = 11). Median time in delay from diagnosis to treatment initiation was 26 days (range 7-117). Reasons for delay included: health systems challenges (administrative hurdles, medication stock, clinic hours), burden of care on families and caregiver perceptions of disease severity.
CONCLUSION: Reasons for delay in treatment initiation are complex. Interventions to streamline administrative processes and tools to identify and support families at risk for delays in treatment initiation are urgently needed.

Entities:  

Mesh:

Year:  2020        PMID: 33317668      PMCID: PMC7913997          DOI: 10.5588/ijtld.20.0079

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN: 1027-3719            Impact factor:   2.373


  26 in total

Review 1.  Diagnosis and treatment of paediatric tuberculosis: An insight review.

Authors:  Nityananda Mandal; Parveen Kumar Anand; Subhash Gautam; Shritam Das; Tahziba Hussain
Journal:  Crit Rev Microbiol       Date:  2017-02-17       Impact factor: 7.624

Review 2.  Delays in diagnosis and treatment of pulmonary tuberculosis in India: a systematic review.

Authors:  Chandrashekhar T Sreeramareddy; Zhi Zhen Qin; Srinath Satyanarayana; Ramnath Subbaraman; Madhukar Pai
Journal:  Int J Tuberc Lung Dis       Date:  2014-03       Impact factor: 2.373

3.  Delay in the diagnosis, notification and initiation of treatment and compliance in children with tuberculosis.

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4.  Barriers to the diagnosis of childhood tuberculosis: a qualitative study.

Authors:  S S Chiang; S Roche; C Contreras; V Alarcón; H Del Castillo; M C Becerra; L Lecca
Journal:  Int J Tuberc Lung Dis       Date:  2015-10       Impact factor: 2.373

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Authors:  Sandra M Newton; Andrew J Brent; Suzanne Anderson; Elizabeth Whittaker; Beate Kampmann
Journal:  Lancet Infect Dis       Date:  2008-08       Impact factor: 25.071

6.  Patient and health care system delays in the start of tuberculosis treatment in Norway.

Authors:  Mohamed Guled Farah; Jens Henning Rygh; Tore W Steen; Randi Selmer; Einar Heldal; Gunnar Bjune
Journal:  BMC Infect Dis       Date:  2006-02-24       Impact factor: 3.090

Review 7.  Factors associated with patient and provider delays for tuberculosis diagnosis and treatment in Asia: a systematic review and meta-analysis.

Authors:  Jing Cai; Xianhua Wang; Aiguo Ma; Qiuzhen Wang; Xiuxia Han; Yong Li
Journal:  PLoS One       Date:  2015-03-25       Impact factor: 3.240

8.  Patient Reported Delays in Seeking Treatment for Tuberculosis among Adult and Pediatric TB Patients and TB Patients Co-Infected with HIV in Lima, Peru: A Qualitative Study.

Authors:  Valerie A Paz-Soldan; Rebecca E Alban; Christy Dimos Jones; Amy R Powell; Richard A Oberhelman
Journal:  Front Public Health       Date:  2014-12-22

9.  Fighting TB stigma: we need to apply lessons learnt from HIV activism.

Authors:  Amrita Daftary; Mike Frick; Nandita Venkatesan; Madhukar Pai
Journal:  BMJ Glob Health       Date:  2017-10-31

Review 10.  Barriers to initiating tuberculosis treatment in sub-Saharan Africa: a systematic review focused on children and youth.

Authors:  Brittney J Sullivan; B Emily Esmaili; Coleen K Cunningham
Journal:  Glob Health Action       Date:  2017       Impact factor: 2.640

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  1 in total

1.  [Impact of SARS-CoV-2 pandemic on adolescents living with HIV in Lima, Peru].

Authors:  Renato A Errea; Milagros Wong; Liz Senador; Alicia Ramos; Karen Ramos; Jerome T Galea; Leonid Lecca; Hugo Sánchez; Carlos Benites; Molly F Franke
Journal:  Rev Peru Med Exp Salud Publica       Date:  2021-06-25
  1 in total

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