| Literature DB >> 33299571 |
William Christopher Newman1, Ankur Patel2, Jacob L Goldberg3, Mark H Bilsky4.
Abstract
Spine metastases are very common in cancer patients often requiring urgent assessment and the initiation of therapy. Treatment paradigms have changed exponentially over the past decade with the evolution and integration of stereotactic body radiotherapy, minimally invasive spine techniques, and systemic options including biologics and checkpoint inhibitors. These advances necessitate multidisciplinary assessments and interventions to optimize outcomes. The NOMS framework provides a mechanism for all practitioners to evaluate the 4 sentinel assessments required to make decisions in patients with spine metastases: Neurologic, Oncologic, Mechanical Stability, and Systemic disease. The NOMS framework is continuously updated with the integration of newer technologies and evidence-based medicine as they become available. This paper presents the current iteration of NOMS with a focus on the role of medical and neuro-oncologists in the assessment and treatment of metastatic spine tumors.Entities:
Keywords: NOMS; decision making; spine metastases; stereotactic radiosurgery
Year: 2020 PMID: 33299571 PMCID: PMC7705527 DOI: 10.1093/nop/npaa056
Source DB: PubMed Journal: Neurooncol Pract ISSN: 2054-2577