Sabina Cisa-Wieczorek1, María Isabel Hernández-Alvarez2,3. 1. Laboratory of Hematology, Department of Hematology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, IIB Sant Pau, 08041 Barcelona, Spain. 2. Departament de Bioquímica i Biomedicina Molecular, Facultat de Biologia, Universitat de Barcelona, 08028 Barcelona, Spain. 3. Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Abstract
Lipids are important molecules for human health. The quantity and quality of fats consumed in the diet have important effects on the modulation of both the natural biosynthesis and degradation of lipids. There is an important number of lipid-failed associated metabolic diseases and an increasing number of studies suggesting that certain types of lipids might be beneficial to the treatment of many metabolic diseases. The aim of the present work is to expose an overview of de novo biosynthesis, storage, and degradation of lipids in mammalian cells, as well as, to review the published data describing the beneficial effects of these processes and the potential of some dietary lipids to improve metabolic diseases.
n class="Chemical">Lipids are important molecules for human health. The quantity and quality of fats consumed in the diet have important effects on the modulation of both the natural biosynthesis and degradation of lipids. There is an important number of lipid-failed associated metabolic diseases and an increasing number of studies suggesting that certain types of lipids might be beneficial to the treatment of many metabolic diseases. The aim of the present work is to expose an overview of de novo biosynthesis, storage, and degradation of lipids in mammalian cells, as well as, to review the published data describing the beneficial effects of these processes and the potential of some dietary lipids to improve metabolic diseases.
Authors: Anna Chiara Nascimbeni; Francesca Giordano; Nicolas Dupont; Daniel Grasso; Maria I Vaccaro; Patrice Codogno; Etienne Morel Journal: EMBO J Date: 2017-05-26 Impact factor: 11.598
Authors: Krishnakant G Soni; Gonzalo A Mardones; Rachid Sougrat; Elena Smirnova; Catherine L Jackson; Juan S Bonifacino Journal: J Cell Sci Date: 2009-06-01 Impact factor: 5.285