Background: Accurate monitoring of skin surface temperatures is necessary to ensure treatment quality during superficial hyperthermia. A high-resolution thermal monitoring sheet (TMS) was developed to monitor the skin surface temperature distribution. The influence of the TMS on applicator performance was investigated, feasibility and ability to reliably monitor the temperature distribution were evaluated in a clinical study. Methods: Phantom experiments were performed to determine the influence of the TMS on power deposition patterns, applicator efficiency, and heat transfer of the water bolus for 434 and 915 MHz applicators. Clinical feasibility was evaluated in 10 women with locoregional recurrent breast cancer. Skin surface temperatures during consecutive treatments were monitored alternatingly with either standard Amsterdam UMC thermometry or TMS. Treatments were compared using (generalized) linear mixed models. Results: The TMS did not significantly affect power deposition patterns and applicator efficiency (1-2%), the reduced heat transfer of the water boluses (51-56%) could be compensated by adjusting the water bolus flow. Skin surface temperatures were monitored reliably, and no alteration of thermal toxicity was observed compared to standard Amsterdam UMC thermometry. Conclusion: Clinical application of the TMS is feasible. Power deposition patterns and applicator efficiency were not affected. Surface temperatures were monitored reliably.
Background: Accurate monitoring of skin surface temperatures is necessary to ensure treatment quality during superficial hyperthermia. A high-resolution thermal monitoring sheet (TMS) was developed to monitor the skin surface temperature distribution. The influence of the TMS on applicator performance was investigated, feasibility and ability to reliably monitor the temperature distribution were evaluated in a clinical study. Methods: Phantom experiments were performed to determine the influence of the TMS on power deposition patterns, applicator efficiency, and heat transfer of the water bolus for 434 and 915 MHz applicators. Clinical feasibility was evaluated in 10 women with locoregional recurrent breast cancer. Skin surface temperatures during consecutive treatments were monitored alternatingly with either standard Amsterdam UMC thermometry or TMS. Treatments were compared using (generalized) linear mixed models. Results: The TMS did not significantly affect power deposition patterns and applicator efficiency (1-2%), the reduced heat transfer of the water boluses (51-56%) could be compensated by adjusting the water bolus flow. Skin surface temperatures were monitored reliably, and no alteration of thermal toxicity was observed compared to standard Amsterdam UMC thermometry. Conclusion: Clinical application of the TMS is feasible. Power deposition patterns and applicator efficiency were not affected. Surface temperatures were monitored reliably.
Authors: Akke Bakker; Remko Zweije; Geertjan van Tienhoven; H Petra Kok; Jan Sijbrands; Desirée van den Bongard; Coen Rasch; Hans Crezee Journal: Phys Med Biol Date: 2020-06-11 Impact factor: 3.609
Authors: H Petra Kok; Martijn De Greef; Davi Correia; Paul J Zum Vörde Sive Vörding; Gerard Van Stam; Edward A Gelvich; Arjan Bel; Johannes Crezee Journal: Int J Hyperthermia Date: 2009 Impact factor: 3.914
Authors: Akke Bakker; M Willemijn Kolff; Rebecca Holman; Caspar M van Leeuwen; Linda Korshuize-van Straten; Rianne de Kroon-Oldenhof; Coen R N Rasch; Geertjan van Tienhoven; Hans Crezee Journal: Int J Radiat Oncol Biol Phys Date: 2017-02-16 Impact factor: 7.038
Authors: M D Sherar; F F Liu; D J Newcombe; B Cooper; W Levin; W B Taylor; J W Hunt Journal: Int J Radiat Oncol Biol Phys Date: 1993-04-02 Impact factor: 7.038
Authors: Akke Bakker; Jacoba van der Zee; Geertjan van Tienhoven; H Petra Kok; Coen R N Rasch; Hans Crezee Journal: Int J Hyperthermia Date: 2019 Impact factor: 3.914