Literature DB >> 33275118

Ectopic pregnancy and epithelial to mesenchymal transition: is there a link?

Heather Flanagan1,2, Chih-Jen Lin2, Lisa L Campbell2, Paddy Horner3,4, Andrew W Horne2, Norah Spears1.   

Abstract

Ectopic pregnancy (EP) is defined as the implantation of an embryo outside of the uterus and is a leading cause of first trimester maternal mortality and morbidity. This article discusses a possible role for epithelial to mesenchymal transition in the pathogenesis of EP, given the notable similarity of protein expression between the two processes.

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Year:  2021        PMID： 33275118      PMCID： PMC7923141          DOI： 10.1530/REP-20-0542

Source DB:  PubMed          Journal:  Reproduction        ISSN： 1470-1626            Impact factor:   3.906


  18 in total

1.  Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression.

Authors:  Sandra Guaita; Isabel Puig; Clara Franci; Marta Garrido; David Dominguez; Eduard Batlle; Elena Sancho; Shoukat Dedhar; Antonio Garcia De Herreros; Josep Baulida
Journal:  J Biol Chem       Date:  2002-08-02       Impact factor: 5.157

2.  Wnt activation downregulates olfactomedin-1 in Fallopian tubal epithelial cells: a microenvironment predisposed to tubal ectopic pregnancy.

Authors:  Suranga P Kodithuwakku; Ronald T K Pang; Ernest H Y Ng; Annie N Y Cheung; Andrew W Horne; Pak-Chung Ho; William S B Yeung; Kai-Fai Lee
Journal:  Lab Invest       Date:  2011-10-03       Impact factor: 5.662

3.  Association between pelvic inflammatory disease, infertility, ectopic pregnancy and the development of ovarian serous borderline tumor, mucinous borderline tumor and low-grade serous carcinoma.

Authors:  L M Stewart; C J R Stewart; K Spilsbury; P A Cohen; S Jordan
Journal:  Gynecol Oncol       Date:  2020-01-23       Impact factor: 5.482

4.  Effects of cigarette smoke extracts on the progression and metastasis of human ovarian cancer cells via regulating epithelial-mesenchymal transition.

Authors:  So-Ye Jeon; Ryeo-Eun Go; Jae-Rim Heo; Cho-Won Kim; Kyung-A Hwang; Kyung-Chul Choi
Journal:  Reprod Toxicol       Date:  2016-06-17       Impact factor: 3.143

5.  Benzo(a)pyrene inhibits endometrial cell apoptosis in early pregnant mice via the WNT5A pathway.

Authors:  Ting Yi; Min Liu; Xueyan Li; Xueqing Liu; Yubin Ding; Junlin He; Hanting Xu; Rufei Gao; Xinyi Mu; Yanqing Geng; Yingxiong Wang; Xuemei Chen
Journal:  J Cell Physiol       Date:  2018-11-15       Impact factor: 6.384

6.  In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cells.

Authors:  Yusuke Yamamoto; Gang Ning; Brooke E Howitt; Karishma Mehra; Lingyan Wu; Xia Wang; Yue Hong; Florian Kern; Tay Seok Wei; Ting Zhang; Niranjan Nagarajan; Debargha Basuli; Suzy Torti; Molly Brewer; Mahesh Choolani; Frank McKeon; Christopher P Crum; Wa Xian
Journal:  J Pathol       Date:  2016-01-09       Impact factor: 7.996

Review 7.  Wnt signaling pathway protein LEF1 in cancer, as a biomarker for prognosis and a target for treatment.

Authors:  Larion Santiago; Garrett Daniels; Dongwen Wang; Fang-Ming Deng; Peng Lee
Journal:  Am J Cancer Res       Date:  2017-06-01       Impact factor: 6.166

8.  Diagnosis and management of ectopic pregnancy.

Authors:  Vanitha N Sivalingam; W Colin Duncan; Emma Kirk; Lucy A Shephard; Andrew W Horne
Journal:  J Fam Plann Reprod Health Care       Date:  2011-07-04

9.  The role of leukemia inhibitory factor in tubal ectopic pregnancy.

Authors:  T Krishnan; A Winship; S Sonderegger; E Menkhorst; A W Horne; J Brown; J-G Zhang; N A Nicola; S Tong; E Dimitriadis
Journal:  Placenta       Date:  2013-09-13       Impact factor: 3.481

10.  The association between smoking and ectopic pregnancy: why nicotine is BAD for your fallopian tube.

Authors:  Andrew W Horne; Jeremy K Brown; Junko Nio-Kobayashi; Hazirah B Z Abidin; Zety E H A Adin; Lyndsey Boswell; Stewart Burgess; Kai-Fai Lee; W Colin Duncan
Journal:  PLoS One       Date:  2014-02-20       Impact factor: 3.240
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