Marian Jarlenski1, Elizabeth E Krans. 1. Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA (MJ); Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine and Magee-Womens Research Institute, Pittsburgh, PA (EEK).
Abstract
OBJECTIVES: Substance use in pregnancy is increasing in the United States (US), although little is know about co-occurring substance use disorders in pregnancy. Our objective was to determine the prevalence and patterns of co-occurring substance use disorders identified at delivery hospitalizations among US women. METHODS: Using data from the National Inpatient Sample, a nationally representative sample of hospitalizations in the US, we identified females ages 15 to 44 years with a delivery hospitalization from 2007 to 2016 (weighted N = 38 million). We identified diagnoses for use of any of the following substance use disorders: alcohol, amphetamines, cannabis, cocaine, opioids, sedatives, or tobacco. Using multivariable regression, we calculated the weighted adjusted prevalence of additional substances used within each specific substance use disorder category. RESULTS: Seven percent of women were diagnosed with any substance use disorder at delivery hospitalization (6.5% tobacco, 1% cannabis, 0.5% opioids, and <1% amphetamines, alcohol, cocaine, and sedatives). Among those with any substance use disorder diagnosis, the adjusted prevalence of any co-occurring use disorder was greatest for those who used alcohol (69%), cocaine (69%), amphetamines (63%), and opioids (62%). Among pregnant women who were diagnosed with cocaine, amphetamines, alcohol or opioid use disorder, tobacco (>45% in all groups), and cannabis (>10% in all groups) were the most common additional substances used. Tobacco and cannabis use disorders were commonly diagnosed together. CONCLUSIONS: Co-occurring substance use disorders are common among women with any substance use disorder in pregnancy. Findings support the need for public health efforts to monitor and address multiple, concurrent use of substances in pregnancy.
OBJECTIVES: Substance use in pregnancy is increasing in the United States (US), although little is know about co-occurring substance use disorders in pregnancy. Our objective was to determine the prevalence and patterns of co-occurring substance use disorders identified at delivery hospitalizations among US women. METHODS: Using data from the National Inpatient Sample, a nationally representative sample of hospitalizations in the US, we identified females ages 15 to 44 years with a delivery hospitalization from 2007 to 2016 (weighted N = 38 million). We identified diagnoses for use of any of the following substance use disorders: alcohol, amphetamines, cannabis, cocaine, opioids, sedatives, or tobacco. Using multivariable regression, we calculated the weighted adjusted prevalence of additional substances used within each specific substance use disorder category. RESULTS: Seven percent of women were diagnosed with any substance use disorder at delivery hospitalization (6.5% tobacco, 1% cannabis, 0.5% opioids, and <1% amphetamines, alcohol, cocaine, and sedatives). Among those with any substance use disorder diagnosis, the adjusted prevalence of any co-occurring use disorder was greatest for those who used alcohol (69%), cocaine (69%), amphetamines (63%), and opioids (62%). Among pregnant women who were diagnosed with cocaine, amphetamines, alcohol or opioid use disorder, tobacco (>45% in all groups), and cannabis (>10% in all groups) were the most common additional substances used. Tobacco and cannabis use disorders were commonly diagnosed together. CONCLUSIONS: Co-occurring substance use disorders are common among women with any substance use disorder in pregnancy. Findings support the need for public health efforts to monitor and address multiple, concurrent use of substances in pregnancy.
Authors: Marcela C Smid; Nicole M Stone; Laurie Baksh; Michelle P Debbink; Brett D Einerson; Michael W Varner; Adam J Gordon; Erin A S Clark Journal: Obstet Gynecol Date: 2019-06 Impact factor: 7.661
Authors: Elena V Kuklina; Maura K Whiteman; Susan D Hillis; Denise J Jamieson; Susan F Meikle; Samuel F Posner; Polly A Marchbanks Journal: Matern Child Health J Date: 2007-08-10
Authors: Lewei A Lin; Amy S B Bohnert; Frederic C Blow; Adam J Gordon; Rosalinda V Ignacio; H Myra Kim; Mark A Ilgen Journal: Addiction Date: 2020-07-07 Impact factor: 6.526
Authors: Lindsay K Admon; Gavin Bart; Katy B Kozhimannil; Caroline R Richardson; Vanessa K Dalton; Tyler N A Winkelman Journal: Am J Public Health Date: 2018-11-29 Impact factor: 9.308
Authors: Van T Tong; Patricia M Dietz; Brian Morrow; Denise V D'Angelo; Sherry L Farr; Karilynn M Rockhill; Lucinda J England Journal: MMWR Surveill Summ Date: 2013-11-08
Authors: Sarah C Haight; Jean Y Ko; Van T Tong; Michele K Bohm; William M Callaghan Journal: MMWR Morb Mortal Wkly Rep Date: 2018-08-10 Impact factor: 17.586
Authors: Kelly C Young-Wolff; Varada Sarovar; Lue-Yen Tucker; Deborah Ansley; Nancy Goler; Amy Conway; Allison Ettenger; Tara R Foti; Qiana L Brown; Ellen T Kurtzman; Sara R Adams; Stacey E Alexeeff Journal: JAMA Netw Open Date: 2022-06-01