Literature DB >> 33268977

Successful Treatment of Recurrent Thrombosis Associated with Malignancy with Apixaban and Follow-up for 1 Year.

Timothy Boey1, Ashita Ashish Sule2, Ashish Anil Sule3.   

Abstract

This case report aims to highlight a successful example of using novel oral anticoagulants (NOACs), such as apixaban, to prevent recurrent venous thromboembolism (VTE) in patients with solid-organ malignancy, as an alternative to low-molecular weight heparin (LMWH). Discussed is the case of a 67-year-old woman diagnosed with recurrent thrombosis in the upper-right limb and malignancy of right breast with metastasis to the axillary lymph nodes. Over a follow-up period of more than 1 year, there was no recurrence of VTE and D-dimer decreased, illuminating the possibility of apixaban as an alternative form of treatment for recurrent VTE in patients with malignancy. This appears to be one of the first case reports in Singapore. International College of Angiology. This article is published by Thieme.

Entities:  

Keywords:  antifactor X a; Low-molecular weight heparin; deep vein thrombosis; early; enoxaparin; peak; subclavian

Year:  2019        PMID: 33268977      PMCID: PMC7690988          DOI: 10.1055/s-0039-1694780

Source DB:  PubMed          Journal:  Int J Angiol        ISSN: 1061-1711


  20 in total

1.  Apixaban to Prevent Venous Thromboembolism in Patients with Cancer.

Authors:  Marc Carrier; Karim Abou-Nassar; Ranjeeta Mallick; Vicky Tagalakis; Sudeep Shivakumar; Ariah Schattner; Philip Kuruvilla; Danny Hill; Silvana Spadafora; Katerine Marquis; Mateya Trinkaus; Anna Tomiak; Agnes Y Y Lee; Peter L Gross; Alejandro Lazo-Langner; Robert El-Maraghi; Glenwood Goss; Gregoire Le Gal; David Stewart; Timothy Ramsay; Marc Rodger; Debra Witham; Philip S Wells
Journal:  N Engl J Med       Date:  2018-12-04       Impact factor: 91.245

Review 2.  Direct oral anticoagulants in patients with VTE and cancer: a systematic review and meta-analysis.

Authors:  Maria Cristina Vedovati; Federico Germini; Giancarlo Agnelli; Cecilia Becattini
Journal:  Chest       Date:  2015-02       Impact factor: 9.410

Review 3.  Heparin inhibition of selectin-mediated interactions during the hematogenous phase of carcinoma metastasis: rationale for clinical studies in humans.

Authors:  Nissi M Varki; Ajit Varki
Journal:  Semin Thromb Hemost       Date:  2002-02       Impact factor: 4.180

4.  Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study.

Authors:  J A Heit; M D Silverstein; D N Mohr; T M Petterson; W M O'Fallon; L J Melton
Journal:  Arch Intern Med       Date:  2000-03-27

5.  Microparticle-associated tissue factor activity: a link between cancer and thrombosis?

Authors:  M E T Tesselaar; F P H T M Romijn; I K Van Der Linden; F A Prins; R M Bertina; S Osanto
Journal:  J Thromb Haemost       Date:  2006-12-13       Impact factor: 5.824

6.  Apixaban for extended treatment of venous thromboembolism.

Authors:  Giancarlo Agnelli; Harry R Buller; Alexander Cohen; Madelyn Curto; Alexander S Gallus; Margot Johnson; Anthony Porcari; Gary E Raskob; Jeffrey I Weitz
Journal:  N Engl J Med       Date:  2012-12-08       Impact factor: 91.245

7.  Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism.

Authors:  Gary E Raskob; Nick van Es; Peter Verhamme; Marc Carrier; Marcello Di Nisio; David Garcia; Michael A Grosso; Ajay K Kakkar; Michael J Kovacs; Michele F Mercuri; Guy Meyer; Annelise Segers; Minggao Shi; Tzu-Fei Wang; Erik Yeo; George Zhang; Jeffrey I Zwicker; Jeffrey I Weitz; Harry R Büller
Journal:  N Engl J Med       Date:  2017-12-12       Impact factor: 91.245

8.  Extended Treatment with Apixaban for Venous Thromboembolism Prevention in the Netherlands: Clinical and Economic Effects.

Authors:  Lisa A de Jong; Judith J Gout-Zwart; Jelena Stevanovic; Harrie Rila; Mike Koops; Menno V Huisman; Maarten J Postma
Journal:  TH Open       Date:  2018-09-26

9.  Apixaban for the treatment of cancer-associated venous thromboembolism and left atrial appendage thrombus refractory to optimal anticoagulation with warfarin: a case report.

Authors:  Masashi Koga; Atsuhiko Sugimoto; Masaki Furo; Harukazu Iseki
Journal:  Eur Heart J Case Rep       Date:  2018-11-26

Review 10.  Venous Thromboembolism in Cancer: An Update of Treatment and Prevention in the Era of Newer Anticoagulants.

Authors:  Waqas Qureshi; Zeeshan Ali; Waseem Amjad; Zaid Alirhayim; Hina Farooq; Shayan Qadir; Fatima Khalid; Mouaz H Al-Mallah
Journal:  Front Cardiovasc Med       Date:  2016-07-28
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