Jan Mieszkowski1, Błażej Stankiewicz2, Andrzej Kochanowicz1, Bartłomiej Niespodziński2, Tomasz Kowalik2, Michał Żmijewski3, Konrad Kowalski4, Rafał Rola4,5, Tomasz Bieńkowski4, Jędrzej Antosiewicz6. 1. Department of Gymnastics and Dance, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland. 2. Institute of Physical Education, Kazimierz Wielki University, 85-064 Bydgoszcz, Poland. 3. Department of Histology, Medical University of Gdańsk, 80-211 Gdansk, Poland. 4. Masdiag Sp. z o.o. Company, 01-882 Warsaw, Poland. 5. Chair of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, 87-100 Toruń, Poland. 6. Department of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, 80-210 Gdansk, Poland.
Abstract
PURPOSE: While an increasing number of studies demonstrate the importance of vitamin D for athletic performance, the effects of any type of exercise on vitamin D metabolism are poorly characterized. We aimed to identify the responses of some vitamin D metabolites to ultra-marathon runs. METHODS: A repeated-measures design was implemented, in which 27 amateur runners were assigned into two groups: those who received a single dose of vitamin D3 (150,000 IU) 24 h before the start of the marathon (n = 13) and those (n = 14) who received a placebo. Blood samples were collected 24 h before, immediately after, and 24 h after the run. RESULTS: In both groups of runners, serum 25(OH)D3, 24,25(OH)2D3, and 3-epi-25(OH)D3 levels significantly increased by 83%, 63%, and 182% after the ultra-marathon, respectively. The increase was most pronounced in the vitamin D group. Body mass and fat mass significantly decreased after the run in both groups. CONCLUSIONS: Ultra-marathon induces the mobilization of vitamin D into the blood. Furthermore, the 24,25(OH)2D3 and 3-epi-25(OH)D3 increases imply that the exercise stimulates vitamin D metabolism.
RCT Entities:
PURPOSE: While an increasing number of studies demonstrate the importance of vitamin D for athletic performance, the effects of any type of exercise on vitamin D metabolism are poorly characterized. We aimed to identify the responses of some vitamin D metabolites to ultra-marathon runs. METHODS: A repeated-measures design was implemented, in which 27 amateur runners were assigned into two groups: those who received a single dose of vitamin D3 (150,000 IU) 24 h before the start of the marathon (n = 13) and those (n = 14) who received a placebo. Blood samples were collected 24 h before, immediately after, and 24 h after the run. RESULTS: In both groups of runners, serum 25(OH)D3, 24,25(OH)2D3, and 3-epi-25(OH)D3 levels significantly increased by 83%, 63%, and 182% after the ultra-marathon, respectively. The increase was most pronounced in the vitamin D group. Body mass and fat mass significantly decreased after the run in both groups. CONCLUSIONS: Ultra-marathon induces the mobilization of vitamin D into the blood. Furthermore, the 24,25(OH)2D3 and 3-epi-25(OH)D3 increases imply that the exercise stimulates vitamin D metabolism.
Authors: Ricardo J S Costa; Beat Knechtle; Mark Tarnopolsky; Martin D Hoffman Journal: Int J Sport Nutr Exerc Metab Date: 2019-04-03 Impact factor: 4.599
Authors: Vanessa D Sherk; Carmen Chrisman; Jessica Smith; Kaelin C Young; Harshvardhan Singh; Michael G Bemben; Debra A Bemben Journal: J Clin Densitom Date: 2012-08-16 Impact factor: 2.617
Authors: Miriam Blum; Gregory Dolnikowski; Elias Seyoum; Susan S Harris; Sarah L Booth; James Peterson; Edward Saltzman; Bess Dawson-Hughes Journal: Endocrine Date: 2008-03-13 Impact factor: 3.633
Authors: Daniel J Owens; Jonathan C Y Tang; Warren J Bradley; Andy S Sparks; William D Fraser; James P Morton; Graeme L Close Journal: Med Sci Sports Exerc Date: 2017-02 Impact factor: 5.411
Authors: Karolina Śledzińska; Piotr Landowski; Michał A Żmijewski; Barbara Kamińska; Konrad Kowalski; Anna Liberek Journal: Nutrients Date: 2022-02-28 Impact factor: 5.717
Authors: Anna Książek; Aleksandra Zagrodna; Małgorzata Słowińska-Lisowska; Giovanni Lombardi Journal: Front Physiol Date: 2022-07-08 Impact factor: 4.755
Authors: Katarzyna Micielska; Marta Flis; Jakub Antoni Kortas; Ewa Rodziewicz-Flis; Jędrzej Antosiewicz; Krystian Wochna; Giovanni Lombardi; Ewa Ziemann Journal: Nutrients Date: 2021-12-08 Impact factor: 5.717