| Literature DB >> 3324619 |
P P Liberski1, W Papierz, J Alwasiak.
Abstract
A 32-year-old man with rapidly progressive dementia, pyramidal signs, myoclonic jerks and dystonic movements died following brain biopsy. neuropathological examination revealed minimal neuronal loss accompanied by mild spongiform change and astrocytic reaction. Numerous plaques and neurofibrillary tangles composed of paired helical filaments dominated the ultrastructural picture. This patient had features of both Creutzfeldt-Jakob disease and Alzheimer's disease, providing additional support for the existence of an overlap between these disorders.Entities:
Mesh:
Year: 1987 PMID: 3324619 DOI: 10.1111/j.1600-0404.1987.tb03598.x
Source DB: PubMed Journal: Acta Neurol Scand ISSN: 0001-6314 Impact factor: 3.209