Literature DB >> 33219062

Having a Usual Source of Care Is Associated with Longer Telomere Length in a National Sample of Older Adults.

Peter Baltrus1, Chaohua Li1, Anne H Gaglioti1.   

Abstract

OBJECTIVE: To provide a potential biological, mechanistic link for the well-established association between primary care access and reduced mortality, this study sought to measure the impact of having a usual source of health care on leukocyte telomere length (LTL). DATA SOURCES: Our study population included 3202 participants aged 50 to 84 years from National Health and Nutrition Examination Survey 1999 to 2001. STUDY
DESIGN: Cross-sectional Study. LTLs between people with and without a usual source of care were compared using unadjusted and adjusted linear regression models. Fully adjusted models accounted for demographic characteristics, health conditions, and health behaviors. PRINCIPAL
FINDINGS: After controlling for individual factors, health conditions, and health behaviors, people who had a usual source of health care had significantly longer LTL (β = 89.8 base pairs, P-value = .005) compared with those without a usual source of care; corresponding to approximately 7 years of life.
CONCLUSIONS: Having a usual source of health care is associated with longer LTL among older adults. This study provides a potential biologic link for the noted association between primary care access and reduced mortality that has been observed at the individual and population level. © Copyright 2020 by the American Board of Family Medicine.

Entities:  

Keywords:  Aging; Cross-Sectional Studies; Healthy Aging; Leukocytes; Linear Models; Nutrition Surveys; Primary Health Care; Telomere

Year:  2020        PMID: 33219062      PMCID: PMC7758079          DOI: 10.3122/jabfm.2020.06.200008

Source DB:  PubMed          Journal:  J Am Board Fam Med        ISSN: 1557-2625            Impact factor:   2.657


  41 in total

1.  Telomere measurement by quantitative PCR.

Authors:  Richard M Cawthon
Journal:  Nucleic Acids Res       Date:  2002-05-15       Impact factor: 16.971

2.  Receipt of preventive care among adults: insurance status and usual source of care.

Authors:  Jennifer E DeVoe; George E Fryer; Robert Phillips; Larry Green
Journal:  Am J Public Health       Date:  2003-05       Impact factor: 9.308

3.  Telomere length may be associated with hypertension.

Authors:  F-W Lung; C-S Ku; W-T Kao
Journal:  J Hum Hypertens       Date:  2007-11-29       Impact factor: 3.012

4.  Shorter telomere length in Europeans than in Africans due to polygenetic adaptation.

Authors:  Matthew E B Hansen; Steven C Hunt; Rivka C Stone; Kent Horvath; Utz Herbig; Alessia Ranciaro; Jibril Hirbo; William Beggs; Alexander P Reiner; James G Wilson; Masayuki Kimura; Immaculata De Vivo; Maxine M Chen; Jeremy D Kark; Daniel Levy; Thomas Nyambo; Sarah A Tishkoff; Abraham Aviv
Journal:  Hum Mol Genet       Date:  2016-03-02       Impact factor: 6.150

5.  A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

Authors:  R K Moyzis; J M Buckingham; L S Cram; M Dani; L L Deaven; M D Jones; J Meyne; R L Ratliff; J R Wu
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

6.  A quantitative measure of continuity of care.

Authors:  T W Bice; S B Boxerman
Journal:  Med Care       Date:  1977-04       Impact factor: 2.983

Review 7.  Does continuity of care improve patient outcomes?

Authors:  Michael D Cabana; Sandra H Jee
Journal:  J Fam Pract       Date:  2004-12       Impact factor: 0.493

8.  Trends in the Types of Usual Sources of Care: A Shift from People to Places or Nothing at All.

Authors:  Winston Liaw; Anuradha Jetty; Stephen Petterson; Andrew Bazemore; Larry Green
Journal:  Health Serv Res       Date:  2017-08-31       Impact factor: 3.402

9.  The association of longitudinal and interpersonal continuity of care with emergency department use, hospitalization, and mortality among Medicare beneficiaries.

Authors:  Suzanne E Bentler; Robert O Morgan; Beth A Virnig; Fredric D Wolinsky
Journal:  PLoS One       Date:  2014-12-22       Impact factor: 3.240

10.  Leukocyte Telomere Length in Relation to 17 Biomarkers of Cardiovascular Disease Risk: A Cross-Sectional Study of US Adults.

Authors:  David H Rehkopf; Belinda L Needham; Jue Lin; Elizabeth H Blackburn; Ami R Zota; Janet M Wojcicki; Elissa S Epel
Journal:  PLoS Med       Date:  2016-11-29       Impact factor: 11.069

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.