Literature DB >> 33215147

A comparative review of 1,004 orthopaedic trauma patients before and during the COVID-19 pandemic.

Kathryn S S Dayananda1, Scott T Mercer1, Rishi Agarwal1, Tariq Yasin1, Ryan W Trickett1.   

Abstract

AIMS: COVID-19 necessitated abrupt changes in trauma service delivery. We compare the demographics and outcomes of patients treated during lockdown to a matched period from 2019. Findings have important implications for service development.
METHODS: A split-site service was introduced, with a COVID-19 free site treating the majority of trauma patients. Polytrauma, spinal, and paediatric trauma patients, plus COVID-19 confirmed or suspicious cases, were managed at another site. Prospective data on all trauma patients undergoing surgery at either site between 16 March 2020 and 31 May 2020 was collated and compared with retrospective review of the same period in 2019. Patient demographics, injury, surgical details, length of stay (LOS), COVID-19 status, and outcome were compared.
RESULTS: There were 1,004 urgent orthopaedic trauma patients (604 in 2019; 400 in 2020). Significant reductions in time to theatre and LOS stay were observed. COVID-19 positive status was confirmed in 4.5% (n = 18). The COVID-19 mortality rate was 1.8% (n = 7). Day-case surgery comprised 47.8% (n = 191), none testing positive for COVID-19 or developing clinically significant COVID-19 symptoms requiring readmission, at a minimum of 17 days follow-up.
CONCLUSION: The novel split-site service, segregating suspected or confirmed COVID-19 cases, minimized onward transmission and demonstrated improved outcomes regarding time to surgery and LOS, despite altered working patterns and additional constraints. Day-surgery pathways appear safe regarding COVID-19 transmission. Lessons learned require dissemination and should be sustained in preparation for a potential second wave or, the return of a "normal" non-COVID workload.Cite this article: Bone Joint Open 2020;1-9:568-575.
© 2020 Author(s) et al.

Entities:  

Keywords:  COVID-19; Day surgery; Trauma

Year:  2020        PMID: 33215147      PMCID: PMC7659692          DOI: 10.1302/2633-1462.19.BJO-2020-0121.R1

Source DB:  PubMed          Journal:  Bone Jt Open        ISSN: 2633-1462


Segregation of COVID-19 suspicious or confirmed cases from the remainder of the trauma workload minimises opportunity for transmission. Well-structured day surgery pathways appear safe regarding COVID-19 transmission, with important ramifications for the reintroduction of planned surgical care. A consultant delivered service (at the expense of planned surgical care) is effective at minimizing the burden on hospital infrastructure.

Introduction

The coronavirus disease 2019 (COVID-19) pandemic has necessitated radical changes to health and social care.[1] The ‘lockdown’ measures central to the public health response were introduced nationally on 23 March 2020.[2] There has been a gradual relaxation across the UK, with Wales and Scotland pursuing a more restrictive easing than England. The impact of these unprecedented times on trauma services is yet to be fully understood. Planned non-urgent orthopaedic surgery in our region was stopped early in the pandemic (13 March 2020), prioritising trauma care and protecting against unnecessary viral exposure. The British Orthopaedic Association (BOA) have produced guidelines that promote the use of alternative non-surgical treatments where possible to further reduce risk.[3] Additional methods to reduce in-hospital transmission for patients requiring emergency surgery were necessary. Cardiff and Vale University Health Board (CAVUHB) has three hospital sites: University Hospital of Wales ( UHW), University Hospital Llandough (UHL) and the Children’s Hospital for Wales (CHfW). UHW is a tertiary referral trauma centre and imminently becoming the Major Trauma Centre for Wales. The UHW site houses the stand-alone CHfW. UHL is geographically distinct, and houses our planned elective service. In anticipation of the COVID-19 surge, we predicted an overall reduction in trauma surgery caseload. However, the need to treat trauma cases while protecting patients and staff from transmission would necessitate increased theatre time.[4-6] The trauma service was divided across the sites. Polytrauma and spinal injuries were managed at UHW, along with any symptomatic, suspected or confirmed cases of COVID-19. The remaining adult trauma were primarily treated at UHL. Paediatric trauma relocated to the CHfW on shared CEPOD theatre lists. Provision at UHL comprised one seven-day, 12-hour trauma theatre, with acute trauma and rehabilitation wards. A segregated Trauma Ambulatory Care Unit (TACU) consisting of four day-surgery chairs, two trolleys and a dedicated local anaesthetic theatre was available 7 days per week. UHW had access to three COVID-19 positive CEPOD theatres and a COVID-19 free trauma theatre, with one spinal and two general trauma wards. Halted elective surgery enabled split-site staffing with resident consultant delivered care 24 hours per day at each site. This study aims to understand the demographic of trauma patients requiring surgical intervention during the pandemic; understand how our trauma service adjustments maintained safe delivery of care, and compare these outcomes with a cohort from 2019.

Methods

All patients undergoing surgery in the operating theatre from 16 March 2020 to 31 May 2020 were prospectively reviewed (2020 cohort). Retrospective review using our electronic theatre database permitted capture of cases performed in the comparative weeks for 2019 (2019 cohort). Only patients undergoing procedures in theatre were included for analyses, excluding those performed in the emergency department. There were no elective lists in 2020 and thus cases performed on an elective list for subacute trauma in 2019 were excluded from analysis. Patient demographics, surgical details, anaesthetic details, and length of stay (LOS) were recorded (Table I). COVID-19 status and virology investigations for suspected COVID-19 were recorded for the 2020 cohort. Injuries were classified by anatomical region (Table II). Patients with femoral fragility fractures (FFFs), defined clinically and including periprosthetic hip, femoral neck and distal femoral fractures, were considered separately.[7]
Table I.

Cohort demographics.

Demographic2019 (n = 604)2020 (n = 400)
Paediatric cases ( < 16 yrs), n (%)154 (25.5)56 (14)
Adult cases ( ≥ 16 yrs), n (%)450 (74.5)344 (86)
Median age, yrs (IQR) 44 (16 to 71)55 (29 to 75)
Sex, n (%)339:265
Male339 (56.1)189 (47.3)
Female265 (43.9)211 (52.7)
Operating site
UHW568 (94.04)185 (46.25
UHL0 (0.00)207 (51.75)
CHFW36 (5.96)8 (2.00)
Sub-cohorts
FFF 113 (18.7)121 (30.2
Median age, yrs (IQR)82 (73.5 to 88)83 (73 to 88)
Male41 (36.3)36
Female72 (63.7)85
Non-FFF (including paediatric cases)491279
Median age, yrs (IQR)32 (13 to 59)38 (21 to 58)
Male298 (60.7)153
Female193 (39.3)126

CHfW, Children's Hospital for Wales; FFF, femoral fragility fractures; ;IQR, interquartile range; UHL, University Hospital Llandough; UHW, University Hospital of Wales.

Table II.

Injuries by anatomical region.

Region2019, n (%)2020, n (%)
Foot33 (5.5)14 (3.5)
Ankle48 (7.9)20 (5.0)
Leg42 (7.0)12 (3.0)
Knee43 (7.1)34 (8.5)
Upper leg19 (3.1)12 (3.0)
Hip127 (21.0)126 (31.5)
Spine34 (5.6)7 (1.8)
Shoulder17 (2.8)9 (2.3)
Elbow26 (4.3)13 (3.3)
Forearm22 (3.6)16 (4.0)
Hand and wrist166 (27.5)119 (29.8)
Polytrauma27 (4.5)18 (4.5)
Fragility femoral fractures113 (18.7)121 (30.1)
Cohort demographics. CHfW, Children's Hospital for Wales; FFF, femoral fragility fractures; ;IQR, interquartile range; UHL, University Hospital Llandough; UHW, University Hospital of Wales. Injuries by anatomical region. Theatre records were cross-referenced with electronic hospital records, identifying all inpatient and community investigations, including COVID-19 virology swabs or additional hospital attendances. Importantly, this system is shared by all hospital sites in surrounding health boards, General Practice, and community Public Health Wales testing sites. Any patient undergoing swab testing or admission at any of these sites would be detectable. Analysis was performed in SPSS v. 25 (IBM, Armonk, New York, USA). The Shapiro-Wilk test for normality dictated non-parametric analysis using Mann-Whitney U test and Kruskal-Wallis test for categorical data, with frequencies assessed using chi-squared tests.

Results

There were 1,004 patients identified as having undergone urgent orthopaedic/trauma surgery, 400 in 2020 and 604 in 2019 (Table I). Overall, age was significantly lower in 2019 (p < 0.001, Mann-Whitney U test). However, excluding the paediatric cases, there was no significant difference (p = 0.222, Mann-Whitney U test). Paediatric cases decreased by 64% in 2020, compared to a 24% reduction in adult cases. There was a greater proportion of males treated in 2019 (χ2 (2) = 7.604, p = 0.007, chi-squared test) (Table I). Collectively hand and wrist plus FFFs comprised 60% of all trauma cases in 2020, compared to 46% in 2019 (Table II). Although a similar number of FFFs were treated across both years, there was a significant reduction in the time to surgery. In 2020, 85% of FFF patients received surgery within 24 hours of admission, compared to 60% in 2019 (Table III). There was a statistically significant increase in consultant led surgery (Table III) and an increased use of spinal, regional and local anaesthesia in 2020 (Table IV).
Table III.

Comparison of surgical timing and seniority of lead surgeon.

Category20192020Chi-squared testp-value
Total FFF, n 113 121
Time to theatre, n (%) < 0.001*
< 1 day68 (60.2)103 (85.1)
2 days32 (28.3)11 (9.1)
≥ 3 days13 (11.5)7 (5.8)
Surgeon seniority χ2(2) = 23.43< 0.001
Consultant (led/supervised Supervised Trainer Scrubbed (STS) / Supervised Trainer Un-Scrubbed (STU))50 (44.2)92 (76.0)
Non-consultant63 (55.8)29 (24.0)
Total non-FFF, n 491 279
Time to theatre, n (%)< 0.001[*]
< 1 day372 (75.7)243 (86.7)
2 days23 (4.7)8 (2.9)
≥ 3 days96 (19.6)28 (10.4)
Surgeon seniority χ 2(2) = 17.12< 0.001
Consultant (led/supervised STS/STU)351 (71.5)237 (84.9)
Non-consultant140 (28.5)42 (15.1)

Kruskal-Wallis test.

Chi-squared test.

FFF, femoral fragility fractures; STS, consultant supervised trainer scrubbed; STU, consultant supervised trainer unscrubbed in theatre.

Table IV.

Comparison of anaesthetic choice between 2019 and 2020.

Administered anaesthetic20192020Chi-squared testp-value
GA463 (76.7)289 (72.3)χ2(2) = 2.260.133
GA + regional Block28 (4.6)23 (5.8)χ2(2) = 0.410.522
Regional Block3 (0.5)6 (1.5)χ2(2) = 2.720.171
SA69 (11.4)28 (7)χ2(2) = 4.900.027
LA41 (6.8)54 (13.5)χ2(2) = 11.88< 0.001

Chi-squared test.

GA, general anaesthetic; SA, spinal anaesthetic; ;LA, local anaesthetic.

Comparison of surgical timing and seniority of lead surgeon. Kruskal-Wallis test. Chi-squared test. FFF, femoral fragility fractures; STS, consultant supervised trainer scrubbed; STU, consultant supervised trainer unscrubbed in theatre. Comparison of anaesthetic choice between 2019 and 2020. Chi-squared test. GA, general anaesthetic; SA, spinal anaesthetic; ;LA, local anaesthetic. Inpatient LOS significantly reduced in 2020 for injuries within most anatomical regions (Table V). Analysis of the FFF patients demonstrated a significant reduction in LOS, allowing for some patients who remain as inpatients at the time of analysis (Table V). LOS did not reduce for spinal or polytrauma patients in 2020.
Table V.

Comparison of length of stay between 2019 and 2020.

Injured anatomical regionMedian length of stay, days (IQR)p-value
2019 2020
Foot8 (0.5 to 44.5)0 (0 to 3.25)0.012
Ankle2 (0.25 to 7.5)2 (1 to 7.75)0.497
Leg5 (1 to 16)6.5 (1 to 25.75)0.418
Knee4 (1 to 18)1.5 (0 to 7.25)0.042
Upper leg8 (1 to 13)3 (1.25 to 40)0.968
Fragility factures 26 (11.5 to 40)12 (7 to 20)< 0.001
Fragility fractures#26 (11.5 to 40)13 (7 to 26)< 0.001
Spine8 (4.75 to 25.25)24 (6 to 46)0.569
Shoulder3 (1 to 5.5)0 (0 to 1)0.004
Elbow1.5 (1 to 3.25)1 (0 to 1.5)0.067
Forearm1 (0 to 9)0 (0 to 0.75)0.009
Hand and wrist0 (0 to 2)0 (0 to 0)0.006
Polytrauma6 (1 to 28)32 (8 to 41)0.470

Mann-Whitney U test.

2020 cohort excluding patients not discharged as of 12 June 2020.

2020 cohort including patients not discharged as of 12 June 2020. For this data set we consider 12 June 2020 as the date of discharge.

Comparison of length of stay between 2019 and 2020. Mann-Whitney U test. 2020 cohort excluding patients not discharged as of 12 June 2020. 2020 cohort including patients not discharged as of 12 June 2020. For this data set we consider 12 June 2020 as the date of discharge. Day-case or ‘23:59’ single overnight stay rates increased by 8% (n = 191 in 2020, n = 240 in 2019) (Table VI). A total of 40 patients (20.9%) receiving < 24 hour stay treatment underwent COVID-19 swabs. None were positive or required readmission at a minimum follow-up duration of 17 days following surgery.
Table VI.

Breakdown of day-case surgery

Variable20202019
Total191 (47.8*)240 (40*)
Median age, yrs (IQR)31 (14 to 55)36 (13 to 67.75)
Sex, M:F103:88139:101
Hospital
UHW65 (34)214 (34)
CHfW6 (3.1)26 (3.1)
UHL120 (62.8)0 (62.8)
Anaesthetic
GA132 (69.1)207 (69.1)
GA + regional0 (0)0 (0)
LA50 (26.2)15 (26.2)
Regional6 (3.1)0 (3.1)
Spinal3 (1.6)18 (1.6)
Anatomical region
Foot10 (5.2)10 (5.2)
Ankle6 (3.1)22 (3.1)
Leg4 (2.1)11 (2.1)
Knee17 (8.9)16 (8.9)
Upper leg2 (1)6 (1)
Hip9 (4.7)16 (4.7)
Spine0 (0)2 (0)
Shoulder8 (4.2)5 (4.2)
Elbow10 (5.2)13 (5.2)
Forearm14 (7.3)13 (7.3)
Hand and wrist111 (58.1)124 (58.1)
Pelvis and acetabulum0 (0)2 (0)
COVID-19 status
Not swabbed/asymptomatic151 (79)N/A
Negative40 (20.9)N/A
Positive0 (0)N/A
Subsequent readmission (with minimum 17 days follow-up)0 (0)N/A

UHW, University Hospital Wales; UHL, University Hospital Llandough; CHfW, Children’s Hospital for Wales.

Percentage of overall total.

GA, general anaesthetic; LA, local anaesthetic; N/A, not applicable.

Breakdown of day-case surgery UHW, University Hospital Wales; UHL, University Hospital Llandough; CHfW, Children’s Hospital for Wales. Percentage of overall total. GA, general anaesthetic; LA, local anaesthetic; N/A, not applicable. There were 142 COVID-19 swabs performed. Overall, 18 patients (4.5%) were confirmed positive (Table VII). The 30-day mortality, including all COVID-19 deaths was 4% (n = 16), an increase from 1.2% (n=7) in 2019 (χ2(2) = 7.45; p = 0.006, chi-squared test). Excluding patients with COVID-19, mortality rates were 2.3% (n = 9) in the 2020 cohort, a statistically non-significant increase from 2019 (χ2(2) = 1.2; p = 0.273, chi-squared test) (Table VIII).
Table VII.

COVID-19 status (2020 cohort only).

COVID-19 status2020 cohort
Not tested/asymptomatic, n (%)258 (64.5)
Tested negative, n (%)124 (31.0)
Tested positive, n (%)18 (4.5)
UHW14 (3.5)
UHL4 (1.0)
Time to first positive swab, n (% positive swabs/% overall cohort)
PA1 (5.6/0.3)
DOA2 (11.1/0.5)
Day 21 (5.6/0.3)
Day 30 (0/0)
Day 41 (5.6/0.3)
Day 53 (16.6/0.8)
Day 61 (5.6/0.3)
Day 71 (5.6/0.3)
> Day 78 (44.4/2)

DOA, day of admission; PA, preadmission.

Table VIII.

Summary of 30-day mortality in 2019 and 2020. Last recorded death in 2020 has been 3 June 2020. This is accurate as of 18 June 2020.

Overall inpatient mortality*, n (%)20192020Chi-squared testp-value*
Including COVID-19-positive cases7 (1.2)16 (4.0)χ2(2) = 7.450.006
Excluding COVID-19-positive cases7 (1.2)9 (2.3)χ2(2) = 1.200.27
Fragility femoral fracture6 (0.9)14 (3.5)
Diabetic foot1 (0.2)1 (0.3)
Polytrauma0 (0)1 (0.3)
COVID-19-positiveN/A7 (1.75)
UHWN/A6 (1.5)
UHLN/A1 (0.25)
Tested negativeN/A5 (1.25)
Not testedN/A4 (1.00)

Last recorded death in 2020 was on 3 June 2020. This is accurate as of 18 June 2020.

Chi-squared test.

COVID-19 status (2020 cohort only). DOA, day of admission; PA, preadmission. Summary of 30-day mortality in 2019 and 2020. Last recorded death in 2020 has been 3 June 2020. This is accurate as of 18 June 2020. Last recorded death in 2020 was on 3 June 2020. This is accurate as of 18 June 2020. Chi-squared test. Seven patients (1.8%) with confirmed COVID-19 positive swabs subsequently died. All had relevant comorbidities and a median age of 92 years (median 20; interquartile range (IQR) 75 to 95) (Table IX).
Table IX.

Breakdown of COVID-19 mortality.

AgeSexOperationDOA to DOS, daysDOA to DPS, daysDPS to DOD, daysComorbidities
75MHip hemiarthroplasty0711Dementia
95FHip hemiarthroplasty0129Angina
92FOpen reduction and internal fixation distal femoral fracture058Dementia
AS
PPM
T2DM
95MDynamic hip screw1621Prostate cancer
TIA
HTN
96MIntramedullary nail for proximal femoral fracture044T2DM
AAA
CKD
IHD
ILD
57MRay amputation5812Alcoholic liver cirrhosis
T1DM
87MIntramedullary nail for proximal femoral fracture108IPT
TIA
Prostate cancer
Diverticulosis with hemicolectomy

AAA, abdominal aortic aneurysm; AS, aortic stenosis; CKD, chronic kidney disease; DOA, date of admission; DOD, date of death; DOS, date of surgery; DPS, date of positive swab; HTN, hypertension; IHD, ischaemic heart disease; ILD, interstitial lung disease; IPT, idiopathic thrombocytopenic purpura; PMH, past medical history; PPM, pacemaker for heart block; T2DM, Type 2 diabetes mellitus; TIA, transient ischaemic attack; T1DM, Type 1 diabetes mellitus.

Breakdown of COVID-19 mortality. AAA, abdominal aortic aneurysm; AS, aortic stenosis; CKD, chronic kidney disease; DOA, date of admission; DOD, date of death; DOS, date of surgery; DPS, date of positive swab; HTN, hypertension; IHD, ischaemic heart disease; ILD, interstitial lung disease; IPT, idiopathic thrombocytopenic purpura; PMH, past medical history; PPM, pacemaker for heart block; T2DM, Type 2 diabetes mellitus; TIA, transient ischaemic attack; T1DM, Type 1 diabetes mellitus.

Discussion

Implementation of a split-site trauma service permitted segregation of confirmed and suspected COVID-19 cases. This service model has been shown to be successful elsewhere and our study supports this.[8] Paediatric cases were segregated from adult trauma as the perception in the early stages of the pandemic was that children were considered asymptomatic carriers. [9,10] The 34% comparative reduction in trauma surgery seen in 2020 is likely multifactorial. The extensive public health intervention of “Stay at Home, Protect the NHS, Save Lives” was crucial for limiting the opportunity to sustain injury. This was assisted by school closures, cancellation of sporting activities, reduced socialising, and abandoned mass gatherings often compounded by alcohol and illicit substance use.[6] Generally, injured patients were able to safely receive treatment along pre-COVID-19 decision-making. However, the BOA guidance during the initial period of lockdown recommended greater efforts to manage conditions nonoperatively.[3] Due to this uncertainty, some injuries, which could have been amenable to either operative or nonoperative management, tended to be treated non-surgically, and managed through the fracture clinic.[11] The details or rate of this decision making are not the focus of this study, although we acknowledge a review could reveal important information for the future. The decision to pursue nonoperative management was the result of a risk benefit discussion between the treating consultant and the patient. Anecdotally, many patients appeared reluctant to undergo surgery, even if this was strongly advised. A general fear of hospitals and anaesthesia was particularly prevalent among patients during the first few weeks of lockdown. There was a slight decrease in the proportion of males treated. Female to male ratios were 1:1.3 in 2019 and 1:0.9 in 2020. This may reflect the impact of lockdown preferentially altering the occurrence of injuries typically sustained by males.[12] However, the reasoning behind this is beyond the scope of this paper. The significant increase in local anaesthetic reflects an active effort to reduce the number of patients receiving GA. This reduces the number of aerosol generating procedures and serves to preserve personal protective equipment (PPE). [13] Increased consultant presence during decision making at diagnosis has minimized time spent by patients in hospital prior to undergoing treatment and contributed to a reduction in admissions. There has been a paradigm shift to questioning why a patient requires admission, rather than why a patient is not fit for discharge. Overall LOS reduced between 2019 and 2020. In 2019, lack of theatre availability or specialist surgeon input often led to increased preoperative hospital stay. The TACU opened in November 2019, increasing our day-surgery trauma capabilities. The TACU, as part of a wider change in ambulant trauma pathways and improved day-surgery operating capacity, has facilitated an 80% reduction in admission rate for ambulant trauma patients. The currently unpublished pre-COVID-19 data for TACU shows a similar but smaller trend. LOS has not been reduced in spinal or polytrauma patients. We suspect this reflects a reduced overall number of cases, with an increased proportion of higher energy injuries requiring prolonged inpatient treatment. We accept the possibility some cases may have been miscategorised in the retrospective 2019 cohort, where data collection relies purely on electronic records. Increased consultant availability due to halted elective activity ensured subspecialty consultant input every day of the week. This served to eliminate delays, even for nonambulant patients. Common sense would suggest that reduced LOS is paramount in minimising potential exposure to COVID-19 as well as other important hospital related infections. In a time where NHS expenditure has increased, interventions minimising LOS while maintaining or improving patient safety will carry important cost implications.[14,15] Scheduled day-case surgery is an efficient use of hospital resources, preventing repeated cancellations, admissions and starvation periods. The improved day-surgery pathway has streamlined the service requiring less interaction between clinicians and other allied health-professionals. Given the likelihood that social distancing will remain for the foreseeable future, coupled with a desire to minimize hospital patient-staff contact, these changes will need to persist into the post COVID-19 world. During the study period no formal local guidance was available with regard to day-case trauma surgery and follow-up. No restrictions were deemed necessary or implemented locally for postoperative care, and patients were followed-up in line with normal practice. It was left to senior surgeon discretion whether to recall and with what timeframe but, any follow-up was face-to-face. LOS is a key performance indicator in the National Hip Fracture Database (NHFD) and reduced by more than 56% in the fragility femoral fracture cohort.[16-18] Reasoning is likely multifactorial and is perhaps due to an observed reduction in time to theatre,[19] and relocation to an established arthroplasty unit known for its accelerated rehabilitation and discharge driven care. Additionally, the overall reduced burden of trauma and changes in working patterns have permitted daily consultant orthogeriatric preoperative optimisation and daily consultant orthopaedic and orthogeriatric review. There has been an increase in out of hours support, with a resident 24 hour consultant workforce across most medical and surgical specialties, and seven-day availability of allied health professionals, abolishing the widely debated “weekend effect”.[20] The improved availability of specialist hip arthroplasty surgeons due to cancelled planned care has been crucial in shortening delays to theatre. Finally, the overriding mentality of staff, patients, and relatives has altered with an increased appreciation that inpatient hospital stays are associated with risk. This new fragility fracture pathway has demonstrated positive effects for this vulnerable group of patients and as we return to a ‘normal’ service we aim to maintain this new pathway. During this period routine testing was limited nationally. There were no formal streams established and testing was limited to symptomatic patients only. Despite this we have observed a zero rate of clinically significant COVID-19 infection after day-surgery or 23:59 short-stay surgery.[21,22] We define clinically significant COVID-19 as infection requiring testing or admission. We accept that some patients may have developed symptoms compatible with COVID-19 infection during their postoperative course, remaining sufficiently well to not require medical attention and confirmatory testing. We deem the risk of loss to follow-up minimal, given the unique geographical restrictions presented by lockdown. Thus, we consider the use of COVID-19 swab testing or admission or attendance to secondary care facilities as surrogate markers for clinically significant COVID-19 infection as a valid assumption. This suggests the risk of contracting COVID-19 from a short hospital attendance is minimal. This may provide support for the reintroduction of carefully structured, planned day-surgery operating ensuring to balance clinical priority and risk for each individual case. [23] Overall, 18 patients (4.5%) tested positive for COVID-19, with only four testing positive at our ‘clean’ (UHL) site. Upon demonstrating signs of potential infection, these patients were isolated, before being moved to a COVID-19 ward once the test confirmed a positive status. Across both sites, 45% (n = 8) of the positive patients became positive within five days of admission. With the varying literature concerning incubation period, it is impossible to determine exactly when and where the disease was contracted, with a possibility of community transmission and latent in-hospital incubation.[9,24] Those testing positive later during their admission suggests in-hospital acquisition despite the preventative measures in place. With the rapidly evolving COVID-19 literature, information regarding surgical risk and outcome remains ever-changing.[8,25-28] An international, multicentre, observational study demonstrated high mortality rates in patients undergoing emergency surgery who developed COVID-19 perioperatively.[25] In our cohort there were seven deaths among patients testing positive for COVID-19 (Table VIII) – a mortality of 38.9%. Six of these patients were admitted with fragility femoral fractures (FFFs), a group with a known risk of perioperative mortality. The seventh patient had significant presurgery medical pathology. While there are many potential confounding variables, a comparison of our inpatient mortality, regardless of COVID-19 status, demonstrates an overall mortality in 2019 of 1.2% (n = 7) compared with 4% (n = 16) in 2020. Considering the FFFs only, the mortality was 1% (n = 6) in 2019, 3.5% (n = 14) in 2020 including COVID-19 positive patients and 2% excluding COVID-19 positive patients. This significant increase in mortality due to COVID-19 emphasises the susceptibility of the elderly comorbid community.[9,25] This is an area which warrants further, larger scale work, as we have shown that patients continue to sustain FFFs even during lockdown. In the event of another COVID-19 surge, active injury prevention in this area may reduce unnecessary surgically related deaths. However, these measures are unlikely to have quick dramatic effects and coexisting methods need to be in place for ongoing protection of these patients on admission. We propose it will be most suitable to isolate asymptomatic patients until confirmed negative. This will entail a multitude of challenges related to set up that will vary from unit to unit. These should be pursued and developed within each individual departments’ capabilities to protect the most vulnerable members of our communities. The COVID-19 pandemic has led to a change in the pattern and frequency of adult and paediatric orthopaedic trauma services across Cardiff and Vale University Health Board. Working pattern adaptations utilizing split site working, reallocation of theatres, a consultant led service and a focus on shortened hospital stay have facilitated a safe and effective service. At-risk patient groups remain at-risk during admission and the mortality seen in this group is high. This should inform orthopaedic trauma care in the event of a second surge of COVID-19 infection. Our zero rate of positive COVID-19 cases suggests that day-surgery or 23:59 trauma operating is safe if the injury allows. The apparent safety of day-surgery care could be carefully extrapolated to the return of planned orthopaedic care, thus giving patients and clinicians more information about risk of transmission.
  14 in total

Review 1.  Epidemiology of adult fractures: A review.

Authors:  Charles M Court-Brown; Ben Caesar
Journal:  Injury       Date:  2006-06-30       Impact factor: 2.586

Review 2.  COVID-19: lessons to date from China.

Authors:  Xiaoxia Lu; Yuhan Xing; Gary Wing-Kin Wong
Journal:  Arch Dis Child       Date:  2020-05-12       Impact factor: 3.791

3.  Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study.

Authors: 
Journal:  Lancet       Date:  2020-05-29       Impact factor: 79.321

4.  The Orthopaedic Trauma Service and COVID-19: Practice Considerations to Optimize Outcomes and Limit Exposure.

Authors:  Daniel J Stinner; Christopher Lebrun; Joseph R Hsu; A Alex Jahangir; Hassan R Mir
Journal:  J Orthop Trauma       Date:  2020-07       Impact factor: 2.512

5.  Resuming elective surgery in the time of COVID-19: a safe and comprehensive strategy.

Authors:  Khaled Al-Omar; Sohail Bakkar; Laith Khasawneh; Gianluca Donatini; Paolo Miccoli
Journal:  Updates Surg       Date:  2020-06-03

Review 6.  Global guidance for surgical care during the COVID-19 pandemic.

Authors: 
Journal:  Br J Surg       Date:  2020-04-15       Impact factor: 6.939

7.  The weekend effect: does hospital mortality differ by day of the week? A systematic review and meta-analysis.

Authors:  Kate Honeyford; Elizabeth Cecil; Michelle Lo; Alex Bottle; Paul Aylin
Journal:  BMC Health Serv Res       Date:  2018-11-20       Impact factor: 2.655

Review 8.  Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and myths.

Authors:  Chih-Cheng Lai; Yen Hung Liu; Cheng-Yi Wang; Ya-Hui Wang; Shun-Chung Hsueh; Muh-Yen Yen; Wen-Chien Ko; Po-Ren Hsueh
Journal:  J Microbiol Immunol Infect       Date:  2020-03-04       Impact factor: 4.399

9.  Outbreak of a new coronavirus: what anaesthetists should know.

Authors:  Philip W H Peng; Pak-Leung Ho; Susy S Hota
Journal:  Br J Anaesth       Date:  2020-02-27       Impact factor: 9.166

Review 10.  Preparing to Perform Trauma and Orthopaedic Surgery on Patients with COVID-19.

Authors:  Ricardo Rodrigues-Pinto; Ricardo Sousa; António Oliveira
Journal:  J Bone Joint Surg Am       Date:  2020-06-03       Impact factor: 6.558

View more
  5 in total

1.  Non-COVID outcomes associated with the coronavirus disease-2019 (COVID-19) pandemic effects study (COPES): A systematic review and meta-analysis.

Authors:  Vincent Issac Lau; Sumeet Dhanoa; Harleen Cheema; Kimberley Lewis; Patrick Geeraert; David Lu; Benjamin Merrick; Aaron Vander Leek; Meghan Sebastianski; Brittany Kula; Dipayan Chaudhuri; Arnav Agarwal; Daniel J Niven; Kirsten M Fiest; Henry T Stelfox; Danny J Zuege; Oleksa G Rewa; Sean M Bagshaw
Journal:  PLoS One       Date:  2022-06-24       Impact factor: 3.752

Review 2.  Single vs Dual-site service reconfiguration during Covid-19 pandemic - A tertiary care centre experience in hip fractures and a Scoping review.

Authors:  Milan Muhammad; Sarah Ayton; Shruthi Hejmadi; Jatinder S Minhas; Nicolette Morgan; Anna C Peek
Journal:  J Clin Orthop Trauma       Date:  2022-05-06

3.  A solid and strong beginning.

Authors:  Fares S Haddad
Journal:  Bone Jt Open       Date:  2020-12-07

4.  Impact of COVID-19 on acute trauma and orthopaedic referrals and surgery in the UK during the first wave of the pandemic: a multicentre observational study from the COVid Emergency-Related Trauma and orthopaedics (COVERT) Collaborative.

Authors:  Kapil Sugand; Arash Aframian; Chang Park; Khaled M Sarraf
Journal:  BMJ Open       Date:  2022-01-18       Impact factor: 2.692

5.  The prevalence, mortality, and associated risk factors for developing COVID-19 in hip fracture patients: a systematic review and meta-analysis.

Authors:  Nicholas D Clement; Nathan Ng; Cameron J Simpson; Robyn F L Patton; Andrew James Hall; A Hamish R W Simpson; Andrew D Duckworth
Journal:  Bone Joint Res       Date:  2020-12       Impact factor: 4.410

  5 in total

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