Abigail H Daniels1, Alana M Flexman2, Gianni R Lorello3,4,5,6. 1. Department of Anesthesia and Pain Medicine, Toronto Western Hospital - University Health Network, Toronto, ON, Canada. 2. Department of Anesthesiology, Pharmacology and Therapeutics, The University of British Columbia, Vancouver, BC, Canada. 3. Department of Anesthesia and Pain Medicine, Toronto Western Hospital - University Health Network, Toronto, ON, Canada. Gianni.Lorello@uhn.ca. 4. Department of Anesthesiology and Pain Medicine, The University of Toronto, Toronto, ON, Canada. Gianni.Lorello@uhn.ca. 5. The Wilson Centre, Toronto, ON, Canada. Gianni.Lorello@uhn.ca. 6. Women's College Research Institute, Toronto, ON, Canada. Gianni.Lorello@uhn.ca.