John K Peel1, Gianni R Lorello2,3,4,5. 1. Department of Anesthesiology and Pain Medicine, The University of Toronto, Toronto, ON, Canada. 2. Department of Anesthesiology and Pain Medicine, The University of Toronto, Toronto, ON, Canada. Gianni.Lorello@uhn.ca. 3. University Health Network, Toronto Western Hospital - Department of Anesthesia and Pain Medicine, Toronto, ON, Canada. Gianni.Lorello@uhn.ca. 4. The Wilson Centre, Toronto, ON, Canada. Gianni.Lorello@uhn.ca. 5. Women's College Research Institute, Toronto, ON, Canada. Gianni.Lorello@uhn.ca.