Literature DB >> 3319228

Ferritin and haemosiderin in free radical generation, lipid peroxidation and protein damage.

M J O'Connell1, T J Peters.   

Abstract

Iron storage proteins, ferritin and haemosiderin, release iron to a range of chelators and reducing agents, including citrate, acetate and ascorbate. Released iron promotes both hydroxyl radical formation in the presence of hydrogen peroxide and lipid peroxidation in liposomes. Ferritin protein is modified in such reactions, both by free radical cleavage and addition reactions with aldehyde products of lipid peroxidation.

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Year:  1987        PMID： 3319228     DOI： 10.1016/0009-3084(87)90067-3

Source DB:  PubMed          Journal:  Chem Phys Lipids        ISSN： 0009-3084            Impact factor:   3.329


  6 in total

1.  Photoaffinity labelling of atrial natriuretic factor (ANF)-R1 receptor by underivatized 125I-ANF. Involvement of lipid peroxidation.

Authors:  L Larose; N McNicoll; J J Rondeau; E Escher; A De Lean
Journal:  Biochem J       Date:  1990-04-15       Impact factor: 3.857

2.  Irradiation after surgically induced brain injury in the rat: timing in relation to severity of radiation damage.

Authors:  Selcuk Peker; Ufuk Abacioglu; Ibrahim Sun; Meral Yuksel; M Necmettin Pamir
Journal:  J Neurooncol       Date:  2004-10       Impact factor: 4.130

3.  Comparison of cytosolic products formed in rat liver in response to parenteral and dietary iron loading.

Authors:  P L Ringeling; M I Cleton; M I Huijskes-Heins; W C de Bruijn; H G van Eijk
Journal:  Biol Trace Elem Res       Date:  1992-10       Impact factor: 3.738

4.  Iron release from haemosiderin and ferritin by therapeutic and physiological chelators.

Authors:  M J O'Connell; R J Ward; H Baum; T J Peters
Journal:  Biochem J       Date:  1989-06-15       Impact factor: 3.857

5.  Lysosomal and cytosolic ferritins. A biochemical and electron-spectroscopic study.

Authors:  P L Ringeling; M I Cleton; M J Kroos; L W Sorber; W C de Bruyn; P M Harrison; H G van Eijk
Journal:  Biol Met       Date:  1989

6.  Modification and inactivation of Cu,Zn-superoxide dismutase by the lipid peroxidation product, acrolein.

Authors:  Jung Hoon Kang
Journal:  BMB Rep       Date:  2013-11       Impact factor: 4.778
  6 in total

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