Preparation, analysis, antioxidant activities in vivo of phosphorylated polysaccharide from Momordica charantia.

Momordica charantia (bitter melon) is a kind of medicine and food homologous fruit. The Momordica charantia polysaccharide has the physiological functions of clearing away heat and detoxification, lowering blood sugar, improving immunity and so on. It is an ideal health care product. The extraction of Momordica charantia polysaccharide was carried out by hot water method. The structure of the polysaccharide and its phosphorylated derivative was determined by IR and NMR, which indicated that the chemical modification was successful. The polysaccharide could significantly increase the content of SOD and CAT in serum, liver and spleen tissue of mice, and reduce the content of MDA in serum, liver and spleen tissue to a certain extent.