Literature DB >> 33183623

Potential applications of hydrophobically modified inulin as an active ingredient in functional foods and drugs - A review.

Muhammad Usman1, Chengnan Zhang2, Prasanna Jagannath Patil3, Arshad Mehmood4, Xiuting Li5, Muhammad Bilal6, Junaid Haider7, Shabbir Ahmad8.   

Abstract

Over the past few years, hydrophobically modified inulin (HMI) has gained considerable attention due to its multitudinous features. The targeted release of drugs remains a subject of research interest. Moreover, it is important to explore the properties of short-chain fatty acids (SCFAs) inulin esters because they are less studied. Additionally, HMI has been used to stabilize various dispersion formulations, which have been observed to be safe because inulin is generally recognized as safe (GRAS). However, the results regarding HMI-based dispersion products are dispersed throughout the literature. This comprehensive review is discussed the possible limitations regarding SCFAs inulin esters, real food dispersion formulations, and HMI drugs. The results revealed that SCFAs inulin esters can regulate the human gut microbiota and increase the biological half-life of SCFAs in the human body. This comprehensive review discusses the versatility of HMI as a promising excipient for the production of hydrophobic drugs.
Copyright © 2020 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Controlled release; Emulsions; Encapsulation; Gut microbiota; Hydrophobically modified inulin

Mesh：

Substances：

Year:  2020        PMID： 33183623      PMCID： PMC7536552          DOI： 10.1016/j.carbpol.2020.117176

Source DB:  PubMed          Journal:  Carbohydr Polym        ISSN： 0144-8617            Impact factor:   9.381


  94 in total

1.  Interaction forces in thin liquid films stabilized by hydrophobically modified inulin polymeric surfactant. 2. Emulsion films.

Authors:  D Exerowa; G Gotchev; T Kolarov; Khr Khristov; B Levecke; Th Tadros
Journal:  Langmuir       Date:  2007-02-13       Impact factor: 3.882

2.  Development of a simple, biocompatible and cost-effective Inulin-Diethylenetriamine based siRNA delivery system.

Authors:  C Sardo; R Farra; M Licciardi; B Dapas; C Scialabba; G Giammona; M Grassi; G Grassi; G Cavallaro
Journal:  Eur J Pharm Sci       Date:  2015-04-04       Impact factor: 4.384

3.  Synthesis of amphiphilic aminated inulin via 'click chemistry' and evaluation for its antibacterial activity.

Authors:  Fang Dong; Jun Zhang; Chunwei Yu; Qing Li; Jianming Ren; Gang Wang; Guodong Gu; Zhanyong Guo
Journal:  Bioorg Med Chem Lett       Date:  2014-07-17       Impact factor: 2.823

4.  The interfacial, emulsification and encapsulation properties of hydrophobically modified inulin.

Authors:  S Kokubun; I Ratcliffe; P A Williams
Journal:  Carbohydr Polym       Date:  2018-04-05       Impact factor: 9.381

5.  Synthesis, characterization and in vitro anti-diabetic activity of catechin grafted inulin.

Authors:  Jun Liu; Jian-feng Lu; Juan Kan; Xiao-yuan Wen; Chang-hai Jin
Journal:  Int J Biol Macromol       Date:  2013-12-04       Impact factor: 6.953

6.  Use of acyl phosphonates for the synthesis of inulin esters and their use as emulsion stabilizing agents.

Authors:  Tina M Rogge; Christian V Stevens; Anton Colpaert; Bart Levecke; Karl Booten
Journal:  Biomacromolecules       Date:  2007-02       Impact factor: 6.988

Review 7.  Polyphenols: food sources and bioavailability.

Authors:  Claudine Manach; Augustin Scalbert; Christine Morand; Christian Rémésy; Liliana Jiménez
Journal:  Am J Clin Nutr       Date:  2004-05       Impact factor: 7.045

8.  Hydrophobically modified inulin as an amphiphilic carbohydrate polymer for micellar delivery of paclitaxel for intravenous route.

Authors:  Pratik Muley; Sunny Kumar; Fadoua El Kourati; Siddharth S Kesharwani; Hemachand Tummala
Journal:  Int J Pharm       Date:  2016-01-11       Impact factor: 5.875

9.  Moderate intensity exercise training combined with inulin-propionate ester supplementation increases whole body resting fat oxidation in overweight women.

Authors:  Dalia Malkova; Thelma Polyviou; Eleni Rizou; Konstantinos Gerasimidis; Edward S Chambers; Tom Preston; M Catriona Tedford; Gary Frost; Douglas J Morrison
Journal:  Metabolism       Date:  2019-11-29       Impact factor: 8.694

10.  Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial.

Authors:  Edward S Chambers; Claire S Byrne; Douglas J Morrison; Kevin G Murphy; Tom Preston; Catriona Tedford; Isabel Garcia-Perez; Sofia Fountana; Jose Ivan Serrano-Contreras; Elaine Holmes; Catherine J Reynolds; Jordie F Roberts; Rosemary J Boyton; Daniel M Altmann; Julie A K McDonald; Julian R Marchesi; Arne N Akbar; Natalie E Riddell; Gareth A Wallis; Gary S Frost
Journal:  Gut       Date:  2019-04-10       Impact factor: 23.059
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  1 in total

1.  Influence of guar gum and chitosan enriched with lemon peel essential oil coatings on the quality of pears.

Authors:  Ayesha Iftikhar; Abdur Rehman; Muhammad Usman; Ahmad Ali; Muhammad Mushtaq Ahmad; Qayyum Shehzad; Hina Fatim; Arshad Mehmood; Abdul Moiz; Muhammad Asim Shabbir; Muhammad Faisal Manzoor; Azhari Siddeeg
Journal:  Food Sci Nutr       Date:  2022-03-29       Impact factor: 3.553
  1 in total

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