| Literature DB >> 29801827 |
S Kokubun1, I Ratcliffe1, P A Williams2.
Abstract
Octenyl- and dodecenyl succinic anhydride derivatives (OSA- and DDSA-) of inulin have been synthesised and their solution and interfacial properties have been determined and compared to a commercially available alkylated inulin, Inutec SP1. All samples formed micellar aggregates in solution above a critical concentration (critical aggregation concentration) and were able to 'dissolve' a hydrophobic dye. They were also able to form stable oil-in-water (O/W) emulsions as assessed by measurements of their droplet size as a function of time. DDSA-inulin with a high degree of substitution was found to be effective at encapsulating beta carotene using the solvent evaporation method which yielded a solid which dissolved readily in simulated gastric fluid. The results confirm the potential application of these materials in a number of areas including, drug delivery, pharmaceuticals, neutraceuticals, cosmetics and personal care.Entities:
Keywords: Alkenyl succinic anhydrides; Critical aggregation concentration; Emulsion stabilisation; Encapsulation; Interfacial properties; Inulin
Year: 2018 PMID: 29801827 DOI: 10.1016/j.carbpol.2018.04.018
Source DB: PubMed Journal: Carbohydr Polym ISSN: 0144-8617 Impact factor: 9.381