Literature DB >> 3316473

Synthetic peptide vaccine confers protection against murine malaria.

F Zavala1, J P Tam, P J Barr, P J Romero, V Ley, R S Nussenzweig, V Nussenzweig.   

Abstract

A synthetic peptide, (DPPPPNPN)2D, representing a subunit of the repeat domain of the Plasmodium berghei circumsporozoite protein, was conjugated to tetanus toxoid using bisdiazobenzidine. Immunization of mice and rats with the conjugate induced high serum titers of antibodies to the parasite, and most of the animals were completely protected from malaria infection when challenged with sporozoites.

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Year:  1987        PMID： 3316473      PMCID： PMC2189666          DOI： 10.1084/jem.166.5.1591

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  10 in total

1.  Tert-butoxycarbonylaminoacyl-4-(oxymethyl)-phenylacetamidomethyl-resin, a more acid-resistant support for solid-phase peptide synthesis.

Authors:  A R Mitchell; B W Erickson; M N Ryabtsev; R S Hodges; R B Merrifield
Journal:  J Am Chem Soc       Date:  1976-11-10       Impact factor: 15.419

2.  Development of a sporozoite malaria vaccine.

Authors:  V Nussenzweig; R S Nussenzweig
Journal:  Am J Trop Med Hyg       Date:  1986-07       Impact factor: 2.345

3.  Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon.

Authors:  A Ferreira; L Schofield; V Enea; H Schellekens; P van der Meide; W E Collins; R S Nussenzweig; V Nussenzweig
Journal:  Science       Date:  1986-05-16       Impact factor: 47.728

4.  Rationale for development of a synthetic vaccine against Plasmodium falciparum malaria.

Authors:  F Zavala; J P Tam; M R Hollingdale; A H Cochrane; I Quakyi; R S Nussenzweig; V Nussenzweig
Journal:  Science       Date:  1985-06-21       Impact factor: 47.728

5.  Infectivity of Plasmodium berghei sporozoites measured with a DNA probe.

Authors:  A Ferreira; V Enea; T Morimoto; V Nussenzweig
Journal:  Mol Biochem Parasitol       Date:  1986-05       Impact factor: 1.759

6.  Efficacy of murine malaria sporozoite vaccines: implications for human vaccine development.

Authors:  J E Egan; J L Weber; W R Ballou; M R Hollingdale; W R Majarian; D M Gordon; W L Maloy; S L Hoffman; R A Wirtz; I Schneider
Journal:  Science       Date:  1987-04-24       Impact factor: 47.728

7.  Antibodies to sporozoites: their frequent occurrence in individuals living in an area of hyperendemic malaria.

Authors:  E H Nardin; R S Nussenzweig; I A McGregor; J H Bryan
Journal:  Science       Date:  1979-11-02       Impact factor: 47.728

8.  Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites.

Authors:  D A Herrington; D F Clyde; G Losonsky; M Cortesia; J R Murphy; J Davis; S Baqar; A M Felix; E P Heimer; D Gillessen
Journal:  Nature       Date:  1987 Jul 16-22       Impact factor: 49.962

9.  Peptides as antigens. Importance of orientation.

Authors:  T Dyrberg; M B Oldstone
Journal:  J Exp Med       Date:  1986-10-01       Impact factor: 14.307

10.  Expression in yeast of a Plasmodium vivax antigen of potential use in a human malaria vaccine.

Authors:  P J Barr; H L Gibson; V Enea; D E Arnot; M R Hollingdale; V Nussenzweig
Journal:  J Exp Med       Date:  1987-04-01       Impact factor: 14.307
  10 in total
  35 in total

1.  Genetic restriction of protective immunity to Plasmodium yoelii sporozoites.

Authors:  W R Weiss; M F Good; M R Hollingdale; L H Miller; J A Berzofsky
Journal:  Bull World Health Organ       Date:  1990       Impact factor: 9.408

2.  Combinatorial approach to hepadnavirus-like particle vaccine design.

Authors:  Jean-Noel Billaud; Darrell Peterson; Margaret Barr; Antony Chen; Matti Sallberg; Fermin Garduno; Phillip Goldstein; Wendy McDowell; Janice Hughes; Joyce Jones; David Milich
Journal:  J Virol       Date:  2005-11       Impact factor: 5.103

3.  Comparative antigenicity and immunogenicity of hepadnavirus core proteins.

Authors:  Jean-Noel Billaud; Darrell Peterson; Florian Schödel; Antony Chen; Matti Sallberg; Fermin Garduno; Phillip Goldstein; Wendy McDowell; Janice Hughes; Joyce Jones; David Milich
Journal:  J Virol       Date:  2005-11       Impact factor: 5.103

Review 4.  The circumsporozoite protein of Plasmodium: a mechanism of immune evasion by the malaria parasite?

Authors:  L Schofield
Journal:  Bull World Health Organ       Date:  1990       Impact factor: 9.408

5.  Vaccine T-cell epitope selection by a peptide competition assay.

Authors:  J Kilgus; P Romagnoli; M Guttinger; D Stuber; L Adorini; F Sinigaglia
Journal:  Proc Natl Acad Sci U S A       Date:  1989-03       Impact factor: 11.205

6.  Presentation of T-cell epitopes assembled as multiple-antigen peptides to murine and human T lymphocytes.

Authors:  D Grillot; D Valmori; P H Lambert; G Corradin; G Del Giudice
Journal:  Infect Immun       Date:  1993-07       Impact factor: 3.441

7.  Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies.

Authors:  Diego A Espinosa; Gabriel M Gutierrez; Maricarmen Rojas-López; Amy R Noe; Lirong Shi; Sze-Wah Tse; Photini Sinnis; Fidel Zavala
Journal:  J Infect Dis       Date:  2015-03-11       Impact factor: 5.226

8.  Development of a chimeric Plasmodium berghei strain expressing the repeat region of the P. vivax circumsporozoite protein for in vivo evaluation of vaccine efficacy.

Authors:  Diego A Espinosa; Anjali Yadava; Evelina Angov; Paul L Maurizio; Christian F Ockenhouse; Fidel Zavala
Journal:  Infect Immun       Date:  2013-05-28       Impact factor: 3.441

9.  Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves.

Authors:  Jae-Hoon Choi; Yoonkyung Do; Cheolho Cheong; Hyein Koh; Silvia B Boscardin; Yong-Seok Oh; Leonia Bozzacco; Christine Trumpfheller; Chae Gyu Park; Ralph M Steinman
Journal:  J Exp Med       Date:  2009-02-16       Impact factor: 14.307

10.  A role for immune responses against non-CS components in the cross-species protection induced by immunization with irradiated malaria sporozoites.

Authors:  Marjorie Mauduit; Anne Charlotte Grüner; Rita Tewari; Nadya Depinay; Michèle Kayibanda; Jean-Marc Chavatte; Jean-François Franetich; Andrea Crisanti; Dominique Mazier; Georges Snounou; Laurent Rénia
Journal:  PLoS One       Date:  2009-11-05       Impact factor: 3.240
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