Literature DB >> 33160014

Organoid model: A new hope for pancreatic cancer treatment?

Haidi Chen1, Qifeng Zhuo1, Zeng Ye1, Xiaowu Xu1, Shunrong Ji2.   

Abstract

Pancreatic cancer is a rapidly progressing disease with a poor prognosis. We still have many questions about the pathogenesis, early diagnosis and precise treatment of this disease. Organoids, a rapidly emerging technology, can simulate the characteristics of pancreatic tumors. Using the organoid model of pancreatic cancer, we can study and explore the characteristics of pancreatic cancer, thereby effectively guiding clinical practice and improving patient prognosis. This review introduces the development of organoids, comparisons of organoids with other preclinical models and the status of organoids in basic research and clinical applications for pancreatic cancer.
Copyright © 2020 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Application; Development; Future; Organoid; Pancreatic tumor

Year:  2020        PMID： 33160014     DOI： 10.1016/j.bbcan.2020.188466

Source DB:  PubMed          Journal:  Biochim Biophys Acta Rev Cancer        ISSN： 0304-419X            Impact factor:   10.680


  10 in total

1.  An Independent Prognostic Model Based on Ten Autophagy-Related Long Noncoding RNAs in Pancreatic Cancer Patients.

Authors:  Jiahui Tian; Chunyan Fu; Xuan Zeng; Xiaoxiao Fan; Yi Wu
Journal:  Genet Res (Camb)       Date:  2022-05-14       Impact factor: 1.375

Review 2.  The power and the promise of organoid models for cancer precision medicine with next-generation functional diagnostics and pharmaceutical exploitation.

Authors:  Yu-Shui Ma; Xiao-Li Yang; Rui Xin; Ting-Miao Wu; Yi Shi; Dan Dan Zhang; Hui-Min Wang; Pei-Yao Wang; Ji-Bin Liu; Da Fu
Journal:  Transl Oncol       Date:  2021-05-18       Impact factor: 4.243

3.  Honeycomb-Like Hydrogel Microspheres for 3D Bulk Construction of Tumor Models.

Authors:  Jiachen He; Chichi Chen; Liang Chen; Ruoyu Cheng; Jie Sun; Xingzhi Liu; Lin Wang; Can Zhu; Sihan Hu; Yuan Xue; Jian Lu; Huiling Yang; Wenguo Cui; Qin Shi
Journal:  Research (Wash D C)       Date:  2022-02-07

4.  Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.

Authors:  Zhiwei He; Kun Cai; Zhirui Zeng; Shan Lei; Wenpeng Cao; Xiaowu Li
Journal:  Cell Death Dis       Date:  2022-03-14       Impact factor: 8.469

5.  Prognostic signature based on m6A-related lncRNAs to predict overall survival in pancreatic ductal adenocarcinoma.

Authors:  Qiong Wu; Lei Chen; Dongliu Miao; Yiqi Jin; Zhigang Zhu
Journal:  Sci Rep       Date:  2022-02-23       Impact factor: 4.379

Review 6.  Urological cancer organoids, patients' avatars for precision medicine: past, present and future.

Authors:  Haotian Chen; Wentao Zhang; Niraj Maskey; Fuhan Yang; Zongtai Zheng; Cheng Li; Ruiliang Wang; Pengfei Wu; Shiyu Mao; Junfeng Zhang; Yang Yan; Wei Li; Xudong Yao
Journal:  Cell Biosci       Date:  2022-08-19       Impact factor: 9.584

Review 7.  Applications of human organoids in the personalized treatment for digestive diseases.

Authors:  Qinying Wang; Fanying Guo; Yutao Jin; Yanlei Ma
Journal:  Signal Transduct Target Ther       Date:  2022-09-27

8.  Single-cell sequencing and establishment of an 8-gene prognostic model for pancreatic cancer patients.

Authors:  Xiao Yu; Qiyao Zhang; Shuijun Zhang; Yuting He; Wenzhi Guo
Journal:  Front Oncol       Date:  2022-09-28       Impact factor: 5.738

Review 9.  Single Cell RNA Sequencing: A New Frontier in Pancreatic Ductal Adenocarcinoma.

Authors:  Maroun Bou Zerdan; Malek Shatila; Dhruv Sarwal; Youssef Bouferraa; Morgan Bou Zerdan; Sabine Allam; Merima Ramovic; Stephen Graziano
Journal:  Cancers (Basel)       Date:  2022-09-22       Impact factor: 6.575

Review 10.  A pancreas tumor derived organoid study: from drug screen to precision medicine.

Authors:  Jia Yao; Man Yang; Lawrence Atteh; Pinyan Liu; Yongcui Mao; Wenbo Meng; Xun Li
Journal:  Cancer Cell Int       Date:  2021-07-27       Impact factor: 5.722
  10 in total

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