Literature DB >> 33151614

Racial disparities in preemptive waitlisting and deceased donor kidney transplantation: Ethics and solutions.

Peter P Reese1,2, Sumit Mohan3,4, Kristen L King3, Winfred W Williams5, Vishnu S Potluri1, Meera N Harhay6,7,8, Nwamaka D Eneanya1,2.   

Abstract

Kidney transplantation prior to dialysis, known as "preemptive transplant," enables patients to live longer and avoid the substantial quality of life burdens due to chronic dialysis. Deceased donor kidneys are a public resource that ought to provide health benefits equitably. Unfortunately, White, better educated, and privately insured patients enjoy disproportionate access to preemptive transplantation using deceased donor kidneys. This problem has persisted for decades and is exacerbated by the first-come, first-served approach to kidney allocation for predialysis patients. In this Personal Viewpoint, we describe the diverse barriers to preemptive waitlisting and kidney transplant. The analysis focuses on healthcare system features that particularly disadvantage Black patients, such as the waitlisting eligibility criterion of a single glomerular filtration rate or creatinine clearance ≤20 ml/min, and neglect of wide variation in the rate of progression to end-stage kidney disease (ESKD) in allocating preemptive transplants. We propose initiatives to improve equity including: (1) standardization of waitlisting eligibility criteria related to kidney function; (2) aggressive education for clinicians about early transplant referral; (3) innovations in electronic medical record capabilities; and (4) rapid status 7 listing by centers. If those initiatives fail, the transplant field should consider eliminating preemptive waitlisting and transplantation with deceased donor kidneys.
© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  clinical research / practice; dialysis; disparities; ethics and public policy; ethnicity / race; kidney transplantation / nephrology; organ allocation; organ procurement and allocation; waitlist management

Mesh:

Year:  2020        PMID: 33151614     DOI: 10.1111/ajt.16392

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  10 in total

1.  A Second Chance at Transplant First: Preemptive Repeat Kidney Transplantation.

Authors:  Anne M Huml; Jesse D Schold
Journal:  Kidney360       Date:  2022-01-27

2.  Global Perspective on Kidney Transplantation: United States.

Authors:  Jeffrey H Wang; Allyson Hart
Journal:  Kidney360       Date:  2021-08-19

3.  Comparison of 2021 CKD-EPI Equations for Estimating Racial Differences in Preemptive Waitlisting for Kidney Transplantation.

Authors:  Elaine Ku; Sandra Amaral; Charles E McCulloch; Deborah B Adey; Libo Li; Kirsten L Johansen
Journal:  Clin J Am Soc Nephrol       Date:  2022-09-19       Impact factor: 10.614

4.  Transplant Clinician Opinions on Use of Race in the Estimation of Glomerular Filtration Rate.

Authors:  Mona D Doshi; Neeraj Singh; Benjamin E Hippen; Kenneth J Woodside; Prince Mohan; Hannah L Byford; Matthew Cooper; Darshana M Dadhania; Sruthi Ainapurapu; Krista L Lentine
Journal:  Clin J Am Soc Nephrol       Date:  2021-10       Impact factor: 10.614

5.  Race-Based eGFR Assessment for Kidney Transplantation.

Authors:  Melanie P Hoenig; Martha Pavlakis
Journal:  Clin J Am Soc Nephrol       Date:  2021-10       Impact factor: 10.614

Review 6.  Past and Present Policy Efforts in Achieving Racial Equity in Kidney Transplantation.

Authors:  Irene K Kim; Paulo N Martins; Martha Pavlakis; Nwamaka D Eneanya; Rachel E Patzer
Journal:  Curr Transplant Rep       Date:  2022-05-24

Review 7.  Stony the road we trod: towards racial justice in kidney care.

Authors:  O N Ray Bignall; Deidra C Crews
Journal:  Nat Rev Nephrol       Date:  2021-02       Impact factor: 28.314

Review 8.  Health inequities and the inappropriate use of race in nephrology.

Authors:  Nwamaka D Eneanya; L Ebony Boulware; Jennifer Tsai; Marino A Bruce; Chandra L Ford; Christina Harris; Leo S Morales; Michael J Ryan; Peter P Reese; Roland J Thorpe; Michelle Morse; Valencia Walker; Fatiu A Arogundade; Antonio A Lopes; Keith C Norris
Journal:  Nat Rev Nephrol       Date:  2021-11-08       Impact factor: 42.439

9.  Comparing the Net Benefits of Adult Deceased Donor Kidney Transplantation for a Patient on the Preemptive Waiting List vs a Patient Receiving Dialysis.

Authors:  Bryce A Kiberd; Karthik K Tennankore; Amanda J Vinson
Journal:  JAMA Netw Open       Date:  2022-07-01

10.  Ensuring the Equitable Advancement of American Kidney Health-the Need to Account for Socioeconomic Disparities in the ESRD Treatment Choices Model.

Authors:  Yuvaram N V Reddy; Sri Lekha Tummalapalli; Mallika L Mendu
Journal:  J Am Soc Nephrol       Date:  2020-12-30       Impact factor: 10.121

  10 in total

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