| Literature DB >> 33136135 |
Bryan N Becker1, Jiacong Luo2, Kathryn S Gray2, Carey Colson2, Dena E Cohen2, Stephen McMurray3, Bryan Gregory3, Nathan Lohmeyer3, Steven M Brunelli2.
Abstract
Importance: While several studies have demonstrated the benefit of enrollment in chronic condition special needs plans (C-SNPs) for other chronic diseases (eg, diabetes), there is no evaluation of the association of C-SNPs with outcomes among patients with end-stage kidney disease (ESKD). Objective: To examine whether and to what degree C-SNP enrollment was associated with improved clinical outcomes and quality of life in patients with ESKD. Design, Setting, and Participants: This multicenter cohort study included 2718 patients who were newly enrolled in an ESKD C-SNP between January 1, 2013, and September 30, 2017, and receiving dialysis from DaVita Kidney Care. Patients were followed up until death, loss to follow-up, or end of study (ie, December 31, 2018). Enrollees in C-SNP were matched via multiple clinical and demographic characteristics with 2 different control populations, as follows: (1) those in the same facilities (n = 2545) or (2) those in similar counties (n = 1986). Patients enrolled in CareMore C-SNPs (n = 206) were excluded from the study. Data analysis was conducted June to December 2019. Exposures: Standard ESKD care with dialysis plus access to an integrated care team who worked with the patient and the dialysis team, comprehensive health assessments done by the integrated care team, and access to select benefits (such as vision and dental care) as a C-SNP enrollee. Main Outcomes and Measures: Hospitalizations, mortality, laboratory values indicative of metabolic control, and Kidney Disease Quality of Life 36-item (KDQOL-36) survey scores.Entities:
Mesh:
Year: 2020 PMID: 33136135 PMCID: PMC7607441 DOI: 10.1001/jamanetworkopen.2020.23663
Source DB: PubMed Journal: JAMA Netw Open ISSN: 2574-3805
Characteristics of C-SNP Enrollees and Matched Patients Across Same Facility and Similar County Analyses
| Characteristic | Patients in same facility, No. (%) | Patients in similar counties, No. (%) | ||||
|---|---|---|---|---|---|---|
| Matched (n = 2545) | C-SNP (n = 2545) | Standardized difference, % | Matched (n = 1986) | C-SNP (n = 1986) | Standardized difference, % | |
| Age, mean (SD), y | 57.1 (13.0) | 57.2 (12.9) | 0.7 | 58.1 (12.2) | 57.8 (12.2) | −2.2 |
| Women | 997 (39.2) | 968 (38.0) | −2.3 | 705 (35.5) | 705 (35.5) | 0 |
| Race/ethnicity | ||||||
| White | 399 (15.7) | 404 (15.9) | 6.9 | 277 (14.0) | 277 (14.0) | 0 |
| Black | 537 (21.1) | 553 (21.7) | 472 (23.8) | 472 (23.8) | ||
| Hispanic | 1352 (53.1) | 1328 (52.2) | 1085 (54.6) | 1085 (54.6) | ||
| Asian | 147 (5.8) | 133 (5.2) | 75 (3.8) | 75 (3.8) | ||
| Other or missing | 110 (4.3) | 127 (5.0) | 77 (3.9) | 77 (3.9) | ||
| BMI, mean (SD) | 27.7 (7.0) | 27.7 (6.8) | 1.2 | 28.0 (6.8) | 27.9 (6.6) | −0.9 |
| Etiology | ||||||
| Diabetes | 1227 (48.2) | 1245 (48.9) | 3.2 | 1107 (55.7) | 1107 (55.7) | 0 |
| Hypertension | 736 (28.9) | 735 (28.9) | 579 (29.2) | 579 (29.2) | ||
| Other | 582 (22.9) | 565 (22.2) | 300 (15.1) | 300 (15.1) | ||
| Vintage, mean (SD), mo | 48.0 (41.3) | 46.3 (39.7) | −4.3 | 45.1 (37.1) | 44.2 (37.7) | −2.4 |
| Modality | ||||||
| HHD | <10 | <10 | NA | 0 | 0 | 0 |
| ICHD | 2360 (92.7) | 2360 (92.7) | 1855 (93.4) | 1855 (93.4) | ||
| NOC | NS | NS | 0 | 0 | ||
| PD | 166 (6.5) | 166 (6.5) | 131 (6.6) | 131 (6.6) | ||
| CCI, mean (SD) | 5.1 (1.7) | 5.1 (1.7) | −1.2 | 5.2 (1.6) | 5.2 (1.5) | −1.2 |
| Diabetes | 2042 (80.2) | 2022 (79.5) | −2.0 | 1631 (82.1) | 1661 (83.6) | 4.0 |
| CHF | 254 (10.0) | 249 (9.8) | −0.7 | 194 (9.8) | 184 (9.3) | −1.7 |
| COPD | 60 (2.4) | 63 (2.5) | 0.8 | 44 (2.2) | 46 (2.3) | 0.7 |
| PVD | 88 (3.5) | 89 (3.5) | 0.2 | 72 (3.6) | 68 (3.4) | −1.1 |
| IHD | 321 (12.6) | 314 (12.3) | −0.8 | 231 (11.6) | 229 (11.5) | −0.3 |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CCI, Charlson comorbidity index; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; C-SNP, chronic condition special needs plan; HHD, home hemodialysis; ICHD, in-center hemodialysis; IHD, ischemic heart disease; NOC, nocturnal dialysis; NS, not shown to protect patient privacy; PD, peritoneal dialysis; PVD, peripheral vascular disease; SNP, special needs plan.
C-SNP enrollees and matched patients were exactly matched on this factor.
Figure 1. Hospitalizations Among Chronic Condition Special Needs Plan (C-SNP) Enrollees and Matched Patients Across Same Facility and Similar Counties
IRR indicates incidence rate ratio.
Figure 2. Mortality Among Chronic Condition Special Needs Plan (C-SNP) Enrollees and Matched Patients Across Same Facility and Similar Counties
HR indicates hazard ratio.
Metabolic Parameters Among C-SNP Enrollees and Matched Patients Across Same Facility and Similar County Analyses
| Metabolic parameter | Patients in same facility | Patients in similar counties | ||||
|---|---|---|---|---|---|---|
| Mean (95% CI) | Mean (95% CI) | |||||
| Matched | C-SNP | Matched | C-SNP | |||
| Calcium, mg/dL | 8.9 (8.8-8.9) | 8.9 (8.8-8.9) | .67 | 8.9 (8.8-8.9) | 8.9 (8.8-8.9) | .57 |
| Phosphate, mg/dL | 5.4 (5.3-5.4) | 5.5 (5.4-5.5) | .04 | 5.4 (5.3-5.4) | 5.4 (5.4-5.5) | .07 |
| Potassium, mEq/L | 4.9 (4.8-4.9) | 4.9 (4.8-4.9) | .33 | 4.9 (4.8-4.9) | 4.9 (4.8-4.9) | .83 |
| PTH, pg/dL | 521 (509-533) | 523 (510-535) | .85 | 520 (507-534) | 508 (495-522) | .22 |
Abbreviations: PTH, parathyroid hormone; C-SNP, chronic condition special needs plan.
SI conversion factors: To convert calcium to millimoles per liter, multiply by 0.25; potassium to millimoles per liter, multiply by 1.0; and PTH to nanograms per liter, multiply by 1.
Figure 3. Kidney Disease Quality of Life Scores Among Chronic Condition Special Needs Plan (C-SNP) Enrollees and Matched Patients Across Same Facility and Similar Counties
MCS indicates mental component score; PCS, physical component score.