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Literature DB >> 3313276

Isolation and characterization of the positively acting regulatory gene QUTA from Aspergillus nidulans.

R K Beri¹, H Whittington, C F Roberts, A R Hawkins.

Abstract

The positively acting regulator gene QUTA from Aspergillus nidulans has been identified and located within a cluster of quinic acid utilisation (QUT) genes isolated within a recombinant phage lambda (lambda Q1). The DNA sequence of the QUTA gene reveals a single uninterrupted reading frame coding for a protein of mw 90.416 Kd. The QUTA protein sequence has a protein motif in the form of a putative "DNA finger" that shows strong homology to other such motifs in the GAL4, PPR1, ARGRII, LAC9 and QA1F regulatory gene products of S. cerevisiae, K. lactis and N. crassa. The data presented confirm the view deduced by genetical analysis that the QUTA gene of A. nidulans encodes a protein capable of interacting with QUT specific DNA sequences.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1987 PMID： 3313276 PMCID： PMC306322 DOI： 10.1093/nar/15.19.7991

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

33 in total

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28 in total

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