Literature DB >> 33130842

Clinical characteristics and in-hospital mortality of COVID-19 adult patients in Saudi Arabia.

Samah I Abohamr1, Rami M Abazid, Mubarak A Aldossari, Hala A Amer, Omar S Badhawi, Obaid M Aljunaidi, Shaimaa H Alzarzour, Hiba M Saadeddin, Fayaz A Bhat, Eman Elsheikh.   

Abstract

OBJECTIVES: To provide a detailed study of demographic, baseline comorbidities, clinical features, and outcome for Coronavirus disease 2019 (COVID-19) patients.
METHODS: A record-based case-series study conducted from March 23 to June 15, 2020 in King Saud Medical City, Riyadh, Saudi Arabia. Demographic data, clinical presentation, laboratory investigations, complications, and in-hospital outcome of COVID-19 patients collected with analysis of the clinical characteristics for survivors and deceased.
RESULTS: A total of 768 patients were included. The mean age was 46.36±13.7 years and 76.7% were men. Approximately 96.3% reported more than one comorbidity; diabetes mellitus was the most frequent (46.4%). Fever (84.5%), cough (82.3%), and shortness of breath (79.8%) were the main presenting symptoms. During the follow-up, pneumonia reported in 68.6%, acute respiratory distress syndrome in 32.7%, septic shock in 20.7%, respiratory failure in 20.3%, and acute kidney injury in 19.3%. Approximately 45.8% of enrolled patients required intensive care unit admission. Lung disease (odd ratio [OR]=3.862 with 95% confident interval [CI] (2.455-6.074), obesity (OR=3.732, CI=2.511-5.546), smoking (OR=2.991, CI=2.072-4.317), chronic kidney disease (OR=2.296. CI=1.497-3.521), and diabetes mellitus (OR=2.291, CI=1.714-3.063) are predictors of ICU admission. Fatality ratio was 4.27%; therefore, men were more prevalent in dead group.
CONCLUSION: Coronavirus disease 2019 places a huge burden on healthcare facilities, particularly in patients with comorbidity. Coronavirus disease 2019 patients who are obese and smokers with history of diabetes mellitus have a high risk of death.

Entities:  

Mesh:

Year:  2020        PMID: 33130842     DOI: 10.15537/smj.2020.11.25495

Source DB:  PubMed          Journal:  Saudi Med J        ISSN: 0379-5284            Impact factor:   1.484


  16 in total

1.  Risk factors associated with in-hospital mortality patients with COVID-19 in Saudi Arabia.

Authors:  Mohammed Aljuaid; Hadil Alotair; Farrah Alnajjar; Wadi Alonazi; Hanaa Sharaf; Eman Sheshah; Lolwah Alashgar; Mashael Alshaikh
Journal:  PLoS One       Date:  2022-06-24       Impact factor: 3.752

2.  Cardiac biomarkers and COVID-19: A systematic review and meta-analysis.

Authors:  Wen An; Ju-Seop Kang; Qiuyang Wang; Tae-Eun Kim
Journal:  J Infect Public Health       Date:  2021-07-29       Impact factor: 7.537

3.  Comorbidities and Risk Factors for Severe Outcomes in COVID-19 Patients in Saudi Arabia: A Retrospective Cohort Study.

Authors:  Fatema S Shaikh; Nahier Aldhafferi; Areej Buker; Abdullah Alqahtani; Subhodeep Dey; Saema Abdulhamid; Dalal Ali Mahaii AlBuhairi; Raha Saud Abdulaziz Alkabour; Waad Sami O Atiyah; Sara Bachar Chrouf; Abdussalam Alshehri; Sunday Olusanya Olatunji; Abdullah M Almuhaideb; Mohammed S Alshahrani; Yousof AlMunsour; Vahitha B Abdul-Salam
Journal:  J Multidiscip Healthc       Date:  2021-08-12

4.  Study on clinical characteristics of 173 cases of COVID-19 and effect of glucocorticoid on nucleic acid negative conversion.

Authors:  Enqing Fu; Ruina Ma; Linxu Wang; Han Fu; Wangping Li
Journal:  Am J Transl Res       Date:  2021-05-15       Impact factor: 4.060

Review 5.  The Impact of Tobacco Use on COVID-19 Outcomes: A Systematic Review.

Authors:  Jessica Baker; Nandita Krishnan; Lorien C Abroms; Carla J Berg
Journal:  J Smok Cessat       Date:  2022-01-20

6.  Comparison of comorbidities among severe and non-severe COVID-19 patients in Asian versus non-Asian populations: A systematic review and meta-analysis.

Authors:  Anju Puri; Lin He; Mohan Giri; Chengfei Wu; Qinghua Zhao
Journal:  Nurs Open       Date:  2021-11-10

7.  The Incidence of Acute Pulmonary Embolism with COVID-19 Pneumonia in Saudi Arabia: A Retrospective Single-Center Study.

Authors:  Samah I Abohamr; Mubarak A Aldossari; Hala A Amer; Hiba M Saadeddin; Sara W Abulhamid; Fayaz A Bhat; Eman Elsheikh
Journal:  J Saudi Heart Assoc       Date:  2020-05-06

8.  Awareness and Practice of COVID-19 Precautionary Measures Among Healthcare Professionals in Saudi Arabia.

Authors:  Naif K Binsaleh; Abdulrahman S Bazaid; Abdu Aldarhami; Subuhi Sherwani; Omar W Althomali
Journal:  J Multidiscip Healthc       Date:  2021-06-22

9.  Safety of Tocilizumab in COVID-19 Patients and Benefit of Single-Dose: The Largest Retrospective Observational Study.

Authors:  Ayman M Al-Qaaneh; Fuad H Al-Ghamdi; Sayed AbdulAzeez; J Francis Borgio
Journal:  Pharmaceutics       Date:  2022-03-11       Impact factor: 6.321

10.  Impact of Smoking on COVID-19 Symptoms in Non-Vaccinated Patients: A Matched Observational Study from Qatar.

Authors:  Mohammad Z Haider; Amna Al-Mannai; Sally Al-Sirhan; Ahmed Elsabagh; Nasser Nasser; Noora Al-Quraishi; Amr Ouda; Khadija Erradi; Anas A Ashour; Ishita Gupta; Jazeel Abdulmajeed; Hamad E Al-Romaihi; Devendra Bansal; Omran A H Musa; Elmoubasher Abu Baker Abd Farag; Mohammed H J Al-Thani; Ala-Eddin Al Moustafa
Journal:  J Multidiscip Healthc       Date:  2022-03-17
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