Literature DB >> 33126968

The transcriptomic signature of the aging podocyte.

Dhanunjay Mukhi1, Katalin Susztak2.   

Abstract

Aging is the strongest independent risk factor for chronic kidney disease. Glomerular epithelial cells are unable to proliferate and have limited ability to renew; therefore, podocytes must maintain a delicate intracellular homeostasis that enables them to function and adapt to stress endured during the human life span. Here, Wang et al. performed unbiased transcriptomic analysis of aging podocytes and identified important novel regulators.
Copyright © 2020 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

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Year:  2020        PMID： 33126968      PMCID： PMC9380427          DOI： 10.1016/j.kint.2020.08.004

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   18.998


  9 in total

1.  Global transcriptomic changes occur in aged mouse podocytes.

Authors:  Yuliang Wang; Diana G Eng; Natalya V Kaverina; Carol J Loretz; Abbal Koirala; Shreeram Akilesh; Jeffrey W Pippin; Stuart J Shankland
Journal:  Kidney Int       Date:  2020-06-25       Impact factor: 10.612

2.  Sirt1-Claudin-1 crosstalk regulates renal function.

Authors:  Deepak Nihalani; Katalin Susztak
Journal:  Nat Med       Date:  2013-11       Impact factor: 53.440

3.  A Single-Cell Transcriptome Atlas of the Mouse Glomerulus.

Authors:  Nikos Karaiskos; Mahdieh Rahmatollahi; Anastasiya Boltengagen; Haiyue Liu; Martin Hoehne; Markus Rinschen; Bernhard Schermer; Thomas Benzing; Nikolaus Rajewsky; Christine Kocks; Martin Kann; Roman-Ulrich Müller
Journal:  J Am Soc Nephrol       Date:  2018-05-24       Impact factor: 10.121

4.  Single-Cell RNA Profiling of Glomerular Cells Shows Dynamic Changes in Experimental Diabetic Kidney Disease.

Authors:  Jia Fu; Kemal M Akat; Zeguo Sun; Weijia Zhang; Detlef Schlondorff; Zhihong Liu; Thomas Tuschl; Kyung Lee; John Cijiang He
Journal:  J Am Soc Nephrol       Date:  2019-03-07       Impact factor: 10.121

5.  Pathophysiology of the glomerulus: KI tells the story.

Authors:  Pierre Ronco
Journal:  Kidney Int       Date:  2020-01       Impact factor: 10.612

Review 6.  Emerging role of autophagy in kidney function, diseases and aging.

Authors:  Tobias B Huber; Charles L Edelstein; Björn Hartleben; Ken Inoki; Man Jiang; Daisuke Koya; Shinji Kume; Wilfred Lieberthal; Nicolas Pallet; Alejandro Quiroga; Kameswaran Ravichandran; Katalin Susztak; Sei Yoshida; Zheng Dong
Journal:  Autophagy       Date:  2012-06-13       Impact factor: 16.016

7.  Adiponectin promotes functional recovery after podocyte ablation.

Authors:  Joseph M Rutkowski; Zhao V Wang; Ae Seo Deok Park; Jianning Zhang; Dihua Zhang; Ming Chang Hu; Orson W Moe; Katalin Susztak; Philipp E Scherer
Journal:  J Am Soc Nephrol       Date:  2013-01-18       Impact factor: 10.121

Review 8.  Understanding the kidney one cell at a time.

Authors:  Jihwan Park; Chang Linda Liu; Junhyong Kim; Katalin Susztak
Journal:  Kidney Int       Date:  2019-07-26       Impact factor: 10.612

9.  A single-cell transcriptomic atlas characterizes ageing tissues in the mouse.

Authors: 
Journal:  Nature       Date:  2020-07-15       Impact factor: 49.962
  9 in total
  1 in total

1.  The role of PTEN in puromycin aminonucleoside-induced podocyte injury.

Authors:  Qi Ren; Shengyou Yu; Huasong Zeng; Huimin Xia
Journal:  Int J Med Sci       Date:  2022-08-15       Impact factor: 3.642
  1 in total

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