Literature DB >> 33111167

Prenatal tests for chromosomal abnormalities detection (PTCAD): pregnant women's knowledge in an Italian Population.

Paola Quaresima1, Federica Visconti2, Elena Greco3, Roberta Venturella2, Costantino Di Carlo2.   

Abstract

BACKGROUND: Nowadays several Prenatal Tests for Chromosomal Abnormalities Detection (PTCAD) are available. In those cases in which there is not an Institutional protocol to advise women about the available PTCAD, the choice of which one to undergo is up to the woman and largely depends on her knowledge about them. Therefore, we decided to evaluate, as a primary outcome, knowledge about PTCAD among pregnant women attending our Term Clinic. As a secondary outcome we evaluated the relationship between the patient's knowledge and the subsequently chosen PTCAD.
METHODS: From August 2017 to August 2018 an anonymous questionnaire with multiple-choice answers was administered to all pregnant women attending our Term antenatal Clinic, a tertiary obstetric unit in Catanzaro (Italy).
RESULTS: Three hundred and twenty-five pregnant women were enrolled in the study. We observed that 28.8% of the pregnant women that chose one of the PTCAD, avoided the first trimester combined screening test; among these, 11.4% were in favour of the cell-free foetal DNA test. The latter was erroneously considered diagnostic by 34.3% of the women that had chosen it.
CONCLUSIONS: This study demonstrated that women's knowledge about PTCAD is poor and that there is a potentially dangerous confusion between the words 'screening' and 'diagnostic'. Informative campaigns about PTCAD and the application of dedicated antenatal counselling appointments should be a health-care priority to avoid unnecessary risks and costs for pregnant women and possible legal issues.

Entities:  

Keywords:  Awareness; Down syndrome; Information; Informed consent; Knowledge; Prenatal screening

Mesh:

Year:  2020        PMID: 33111167     DOI: 10.1007/s00404-020-05846-2

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  5 in total

1.  Pregnant women's knowledge and attitudes to prenatal screening for fetal chromosomal abnormalities: Croatian multicentric survey.

Authors:  Vesna Kosec; Ivana Zec; Dubravka Tislarić-Medenjak; Krunoslav Kuna; Ana Maria Simundić; Marta Lajtman-Krizaić; Boris Lovrić; Marko Mimica; Zrinka Komadina Estatiev; Vesna Borgudan
Journal:  Coll Antropol       Date:  2013-06

2.  Information and knowledge about Down syndrome among women and partners after first trimester combined testing.

Authors:  Ellen Ternby; Charlotta Ingvoldstad; Göran Annerén; Peter Lindgren; Ove Axelsson
Journal:  Acta Obstet Gynecol Scand       Date:  2015-01-12       Impact factor: 3.636

Review 3.  The accuracy of cell-free fetal DNA-based non-invasive prenatal testing in singleton pregnancies: a systematic review and bivariate meta-analysis.

Authors:  F L Mackie; K Hemming; S Allen; R K Morris; M D Kilby
Journal:  BJOG       Date:  2016-05-31       Impact factor: 6.531

4.  Knowledge and Attitudes toward Non-invasive Prenatal Testing among Pregnant Japanese Women.

Authors:  Shoko Mikamo; Mikiya Nakatsuka
Journal:  Acta Med Okayama       Date:  2015       Impact factor: 0.892

5.  Accuracy of first-trimester combined test in screening for trisomies 21, 18 and 13.

Authors:  M Santorum; D Wright; A Syngelaki; N Karagioti; K H Nicolaides
Journal:  Ultrasound Obstet Gynecol       Date:  2017-04-26       Impact factor: 7.299

  5 in total
  3 in total

1.  Nationwide implementation of the non-invasive prenatal test: Evaluation of a blended learning program for counselors.

Authors:  Linda Martin; Janneke T Gitsels-van der Wal; Caroline J Bax; Mijntje J Pieters; Jacqueline C I Y Reijerink-Verheij; Robert-Jan Galjaard; Lidewij Henneman
Journal:  PLoS One       Date:  2022-05-02       Impact factor: 3.752

2.  Knowledge and attitude of pregnant women in the Kingdom of Saudi Arabia toward Noninvasive prenatal testing: A single center study.

Authors:  Maaged A Akiel; Mohamud S Mohamud; Emad M Masuadi; Hassan S Alamri
Journal:  Mol Genet Genomic Med       Date:  2022-04-28       Impact factor: 2.473

3.  More than an Incidentaloma: The Nonreportable NIPT.

Authors:  Allison M Jay; Brian Mason; Daniel Lebovic; Paul Chuba
Journal:  Case Rep Obstet Gynecol       Date:  2022-04-30
  3 in total

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