Literature DB >> 33106941

Impact of surgical wait times during summer months on the oncological outcomes following robotic-assisted radical prostatectomy: 10 years' experience from a large Canadian academic center.

Ahmed S Zakaria1, Félix Couture2, David-Dan Nguyen3, Côme Tholomier4, Hanna Shahine1, Franziska Stolzenbach1, Malek Meskawi5, Pierre I Karakiewicz1, Assaad El-Hakim5, Kevin C Zorn6.   

Abstract

PURPOSE: Most Canadian hospitals face significant reductions in operating room access during the summer. We sought to assess the impact of longer wait times on the oncological outcomes of localized prostate cancer patients following robotic-assisted radical prostatectomy (RARP).
METHODS: We conducted a retrospective review of a prospectively maintained RARP database in two high-volume academic centers, between 2010 and 2019. Assessed outcomes included the difference between post-biopsy UCSF-CAPRA and post-surgical CAPRA-S scores, Gleason score upgrade and biochemical recurrence rates (BCR). Multivariable regression analyses (MVA) were used to evaluate the effect of wait times.
RESULTS: A total of 1057 men were included for analysis. Consistent over a 10 year period, summer months had the lowest surgical volumes despite above average booking volumes. The lowest surgical volume occurred during the month of July (7.1 cases on average), which was 35% less than the cohort average. The longest average wait times occurred for patients booked in June (93 ± 69 days, p < 0.001). On MVA, patients booked in June had significantly more chance of having an increase in CAPRA score [HR (95% CI) 1.64 (1.02-2.63); p = 0.04] and in CAPRA risk group [HR (95% CI) 1.82 (1.04-3.19); p = 0.03]. Cohort analysis showed fair correlation between CAPRA-score difference and wait time (Pearson correlation: r =  - 0.062; p = 0.044).
CONCLUSION: Our cohort results demonstrate that conventional RARP wait times are significantly and consistently prolonged during summer months over the past 10 years, with worse post-RARP oncological outcomes in terms of CAPRA scores. Other compensatory mechanisms to sustain consistent yearly operative output should be considered.
© 2020. Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Oncological outcomes; Prostate cancer; Robotic-assisted radical prostatectomy; Surgical wait times

Mesh:

Year:  2020        PMID: 33106941     DOI: 10.1007/s00345-020-03496-2

Source DB:  PubMed          Journal:  World J Urol        ISSN: 0724-4983            Impact factor:   4.226


  4 in total

1.  Robot assisted radical prostatectomy: how I do it. Part II: Surgical technique.

Authors:  Roger F Valdivieso; Pierre-Alain Hueber; Kevin C Zorn
Journal:  Can J Urol       Date:  2013-12       Impact factor: 1.344

Review 2.  Does prolonging the time to prostate cancer surgery impact long-term cancer control: a systematic review of the literature.

Authors:  Fred Saad; Antonio Finelli; George Dranitsaris; Larry Goldenberg; Scott Bagnell; Martin Gleave; Neil Fleshner
Journal:  Can J Urol       Date:  2006-06       Impact factor: 1.344

3.  Robot assisted radical prostatectomy: how I do it. Part I: Patient preparation and positioning.

Authors:  Roger F Valdivieso; Pierre-Alain Hueber; Kevin C Zorn
Journal:  Can J Urol       Date:  2013-10       Impact factor: 1.344

4.  The effect of time from biopsy to radical prostatectomy on adverse pathologic outcomes.

Authors:  Premal Patel; Ryan Sun; Benjamin Shiff; Kiril Trpkov; Geoffrey Thomas Gotto
Journal:  Res Rep Urol       Date:  2019-03-06
  4 in total
  7 in total

1.  Propensity-score analysis comparing perioperative and functional outcomes between XPS 180 W-photovaporization and GreenLight laser enucleation of the prostate: reasons to discard vaporization and move to enucleation.

Authors:  Anis Gasmi; Zine-Eddine Khene; Sonia Guérin; Karim Bensalah; Benoit Peyronnet; Romain Mathieu; Morgan Roupret; Enrique Rijo; Benjamin Pradère; Vincent Misrai
Journal:  World J Urol       Date:  2021-02-15       Impact factor: 4.226

2.  Mid-term functional outcomes of extraperitoneal robot-assisted simple prostatectomy: a single centre experience.

Authors:  Alessio Paladini; Daniel Benamran; Ugo Pinar; Igor Duquesne; Davy Benarroche; Jerome Parra; Christophe Vaessen; Emmanuel Chartier-Kastler; Thomas Seisen; Morgan Roupret
Journal:  J Robot Surg       Date:  2022-02-02

Review 3.  Reasons to overthrow TURP: bring on Aquablation.

Authors:  Iman Sadri; Adel Arezki; Félix Couture; David-Dan Nguyen; Russell Schwartz; Ahmed S Zakaria; Dean Elterman; Enrique Rijo; Vincent Misrai; Thorsten Bach; Claus G Roehrborn; Kevin C Zorn
Journal:  World J Urol       Date:  2020-08-01       Impact factor: 4.226

4.  Impact of the presence of a median lobe on functional outcomes of greenlight photovaporization of the prostate (PVP): an analysis of the Global Greenlight Group (GGG) Database.

Authors:  David-Dan Nguyen; Iman Sadri; Kyle Law; Naeem Bhojani; Dean S Elterman; Ahmed S Zakaria; Adel Arezki; Franck Bruyère; Luca Cindolo; Giovanni Ferrari; Carlos Vasquez-Lastra; Tiago Borelli-Bovo; Edgardo F Becher; Hannes Cash; Maximillian Reimann; Enrique Rijo; Vincent Misrai; Kevin C Zorn
Journal:  World J Urol       Date:  2021-01-03       Impact factor: 4.226

5.  Initial single centre experience of Aquablation of the prostate using the AquaBeam system with athermal haemostasis for the treatment of benign prostatic hyperplasia: 1-year outcomes.

Authors:  Danielle Whiting; Keng Lim Ng; Neil Barber
Journal:  World J Urol       Date:  2021-01-03       Impact factor: 4.226

6.  Excessive waitlists and delays to treatment with low-dose-rate brachytherapy predict an increased risk of recurrence and metastases in intermediate-risk prostatic carcinoma.

Authors:  Rutvij A Khanolkar; Harvey Quon; Kundan Thind; Michael Sia; Michael Roumeliotis; Siraj Husain; Philip McGeachy; Tyler Meyer; Kevin Martell
Journal:  Clin Transl Radiat Oncol       Date:  2021-07-01

7.  Oncologic impact of delaying radical prostatectomy in men with intermediate- and high-risk prostate cancer: a systematic review.

Authors:  Ekaterina Laukhtina; Reza Sari Motlagh; Keiichiro Mori; Fahad Quhal; Victor M Schuettfort; Hadi Mostafaei; Satoshi Katayama; Nico C Grossmann; Guillaume Ploussard; Pierre I Karakiewicz; Alberto Briganti; Mohammad Abufaraj; Dmitry Enikeev; Benjamin Pradere; Shahrokh F Shariat
Journal:  World J Urol       Date:  2021-05-28       Impact factor: 4.226

  7 in total

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