Literature DB >> 33095048

Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing.

Misha Angrist, Rodolphe Barrangou, Françoise Baylis, Carolyn Brokowski, Gaetan Burgio, Arthur Caplan, Carolyn Riley Chapman, George M Church, Robert Cook-Deegan, Bryan Cwik, Jennifer A Doudna, John H Evans, Henry T Greely, Laura Hercher, J Benjamin Hurlbut, Richard O Hynes, Tetsuya Ishii, Samira Kiani, LaTasha Hoskins Lee, Guillaume Levrier, David R Liu, Jeantine E Lunshof, Kerry Lynn Macintosh, Debra J H Mathews, Eric M Meslin, Peter H R Mills, Lluis Montoliu, Kiran Musunuru, Dianne Nicol, Helen O'Neill, Renzong Qiu, Robert Ranisch, Jacob S Sherkow, Sheetal Soni, Sharon Terry, Eric Topol, Robert Williamson, Feng Zhang, Kevin Davies.   

Abstract

In September 2020, a detailed report on Heritable Human Genome Editing was published. The report offers a translational pathway for the limited approval of germline editing under limited circumstances and assuming various criteria have been met. In this perspective, some three dozen experts from the fields of genome editing, medicine, bioethics, law, and related fields offer their candid reactions to the National Academies/Royal Society report, highlighting areas of support, omissions, disagreements, and priorities moving forward.

Entities:  

Mesh:

Year:  2020        PMID: 33095048      PMCID: PMC8935482          DOI: 10.1089/crispr.2020.29106.man

Source DB:  PubMed          Journal:  CRISPR J        ISSN: 2573-1599


  8 in total

1.  Should Long-Term Follow-up Post-Mitochondrial Replacement be Left up to Physicians, Parents, or Offspring?

Authors:  Tetsuya Ishii
Journal:  New Bioeth       Date:  2019-08-20

2.  Questioning the proposed translational pathway for germline genome editing.

Authors:  Françoise Baylis
Journal:  Nat Hum Behav       Date:  2019-03

3.  Heritable Genome Editing and the Downsides of a Global Moratorium.

Authors:  Kerry Lynn Macintosh
Journal:  CRISPR J       Date:  2019-10

4.  Global citizen deliberation on genome editing.

Authors:  John S Dryzek; Dianne Nicol; Simon Niemeyer; Sonya Pemberton; Nicole Curato; André Bächtiger; Philip Batterham; Bjørn Bedsted; Simon Burall; Michael Burgess; Gaetan Burgio; Yurij Castelfranchi; Hervé Chneiweiss; George Church; Merlin Crossley; Jantina de Vries; Mahmud Farooque; Marit Hammond; Baogang He; Ricardo Mendonça; Jennifer Merchant; Anna Middleton; John E J Rasko; Ine Van Hoyweghen; Antoine Vergne
Journal:  Science       Date:  2020-09-18       Impact factor: 47.728

5.  Do CRISPR Germline Ethics Statements Cut It?

Authors:  Carolyn Brokowski
Journal:  CRISPR J       Date:  2018-04

6.  Germline genome editing versus preimplantation genetic diagnosis: Is there a case in favour of germline interventions?

Authors:  Robert Ranisch
Journal:  Bioethics       Date:  2019-08-25       Impact factor: 1.898

7.  Extensive germline genome engineering in pigs.

Authors:  Yanan Yue; Weihong Xu; Yinan Kan; Hong-Ye Zhao; Yixuan Zhou; Xiaobin Song; Jiajia Wu; Juan Xiong; Dharmendra Goswami; Meng Yang; Lydia Lamriben; Mengyuan Xu; Qi Zhang; Yu Luo; Jianxiong Guo; Shengyi Mao; Deling Jiao; Tien Dat Nguyen; Zhuo Li; Jacob V Layer; Mailin Li; Violette Paragas; Michele E Youd; Zhongquan Sun; Yuan Ding; Weilin Wang; Hongwei Dou; Lingling Song; Xueqiong Wang; Lei Le; Xin Fang; Haydy George; Ranjith Anand; Shi Yun Wang; William F Westlin; Marc Güell; James Markmann; Wenning Qin; Yangbin Gao; Hong-Jiang Wei; George M Church; Luhan Yang
Journal:  Nat Biomed Eng       Date:  2020-09-21       Impact factor: 25.671

8.  Safety of Germline Genome Editing for Genetically Related "Future" Children as Perceived by Parents.

Authors:  Tetsuya Ishii; Iñigo de Miguel Beriain
Journal:  CRISPR J       Date:  2019-11-19
  8 in total
  2 in total

Review 1.  Governing Heritable Human Genome Editing: A Textual History and a Proposal for the Future.

Authors:  LeRoy Walters; Robert M Cook-Deegan; Eli Y Adashi
Journal:  CRISPR J       Date:  2021-08

Review 2.  Addressing the dark matter of gene therapy: technical and ethical barriers to clinical application.

Authors:  Kateryna Kratzer; Landon J Getz; Thibaut Peterlini; Jean-Yves Masson; Graham Dellaire
Journal:  Hum Genet       Date:  2021-04-08       Impact factor: 4.132

  2 in total

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