STUDY OBJECTIVES: The purpose of this study was to analyze patients with epiglottic collapse, especially their clinical characteristics related to obstructive sleep apnea and phenotype labeling using drug-induced sleep endoscopy. METHODS: An age-sex matched case-control study was conducted to compare the clinical characteristics of patients with epiglottic collapse (Epi group) and patients without epiglottic collapse (non-Epi group). All patients underwent drug-induced sleep endoscopy January, 2015, to March, 2019, in a tertiary hospital for suspected sleep apnea symptoms. Demographic factors, underlying disease, overnight polysomnography, and their phenotype labeling using drug-induced sleep endoscopy were analyzed. RESULTS: There was no difference in age, sex, the prevalence of hypertension, diabetes, cerebrovascular disease, and coronary artery disease. However, the body mass index was significantly lower in patients in the Epi group (P < .001). Additionally, the apnea-hypopnea index was lower (P = .001), and the lowest oxygen saturation was significantly higher in the Epi group (P = .042). The phenotype labeling on drug-induced sleep endoscopy showed that the prevalence of velum concentric collapse and oropharyngeal lateral wall collapse was lower, and that of tongue-base collapse was higher in the Epi group. Multilevel obstructions were more common in the Epi group. However, the Epi group showed a good response to mandibular advancement or positional therapy. CONCLUSIONS: Although there was no difference in the underlying characteristics and self-reported symptom scores between the groups, the patients with epiglottic collapse showed significantly lower body mass index and obstructive sleep apnea severity. Additionally, patients with epiglottic collapse were expected to respond well to oral devices or positional therapy.
STUDY OBJECTIVES: The purpose of this study was to analyze patients with epiglottic collapse, especially their clinical characteristics related to obstructive sleep apnea and phenotype labeling using drug-induced sleep endoscopy. METHODS: An age-sex matched case-control study was conducted to compare the clinical characteristics of patients with epiglottic collapse (Epi group) and patients without epiglottic collapse (non-Epi group). All patients underwent drug-induced sleep endoscopy January, 2015, to March, 2019, in a tertiary hospital for suspected sleep apnea symptoms. Demographic factors, underlying disease, overnight polysomnography, and their phenotype labeling using drug-induced sleep endoscopy were analyzed. RESULTS: There was no difference in age, sex, the prevalence of hypertension, diabetes, cerebrovascular disease, and coronary artery disease. However, the body mass index was significantly lower in patients in the Epi group (P < .001). Additionally, the apnea-hypopnea index was lower (P = .001), and the lowest oxygen saturation was significantly higher in the Epi group (P = .042). The phenotype labeling on drug-induced sleep endoscopy showed that the prevalence of velum concentric collapse and oropharyngeal lateral wall collapse was lower, and that of tongue-base collapse was higher in the Epi group. Multilevel obstructions were more common in the Epi group. However, the Epi group showed a good response to mandibular advancement or positional therapy. CONCLUSIONS: Although there was no difference in the underlying characteristics and self-reported symptom scores between the groups, the patients with epiglottic collapse showed significantly lower body mass index and obstructive sleep apnea severity. Additionally, patients with epiglottic collapse were expected to respond well to oral devices or positional therapy.
Authors: Soo Kweon Koo; Jang Won Choi; Nam Suk Myung; Hyoung Ju Lee; Yang Jae Kim; Young Joong Kim Journal: Am J Otolaryngol Date: 2013-09-05 Impact factor: 1.808
Authors: Ali Azarbarzin; Melania Marques; Scott A Sands; Sara Op de Beeck; Pedro R Genta; Luigi Taranto-Montemurro; Camila M de Melo; Ludovico Messineo; Olivier M Vanderveken; David P White; Andrew Wellman Journal: Eur Respir J Date: 2017-09-20 Impact factor: 16.671
Authors: Nancy A Collop; W McDowell Anderson; Brian Boehlecke; David Claman; Rochelle Goldberg; Daniel J Gottlieb; David Hudgel; Michael Sateia; Richard Schwab Journal: J Clin Sleep Med Date: 2007-12-15 Impact factor: 4.062
Authors: Sang Hyeon Ahn; Jinna Kim; Hyun Jin Min; Hyo Jin Chung; Jae Min Hong; Jeung-Gweon Lee; Chang-Hoon Kim; Hyung-Ju Cho Journal: PLoS One Date: 2015-08-17 Impact factor: 3.240
Authors: Mistyka S Schar; Taher I Omari; Charmaine M Woods; Charles Cock; Sebastian H Doeltgen; Ching Li Chai-Coetzer; Danny J Eckert; Theodore Athanasiadis; Eng H Ooi Journal: J Clin Sleep Med Date: 2022-04-01 Impact factor: 4.062
Authors: Shi Nee Tan; Jong-Min Kim; Jisun Kim; Chung Man Sung; Hong Chan Kim; Jongho Lee; Sang Chul Lim; David P White; Hyung Chae Yang; D Andrew Wellman Journal: PLoS One Date: 2022-05-24 Impact factor: 3.752
Authors: Carlos O'Connor-Reina; Jose Maria Ignacio Garcia; Peter Baptista; Maria Teresa Garcia-Iriarte; Carlos Casado Alba; Monica Perona; Paz Francisca Borrmann; Laura Rodriguez Alcala; Guillermo Plaza Journal: J Otolaryngol Head Neck Surg Date: 2021-06-30