AIM: To show three patients with soft tissue sarcomas of distal extremities conservatively treated after tumor-board discussion, involving margin-free surgery, exclusive intraoperative radiotherapy, and immediate reconstruction. BACKGROUND: Current guidelines show clear and robust recommendations regarding the composition of the treatment of sarcomas of extremities. However, little evidence exists regarding the application of these treatments depending on the location of the primary neoplasia. Tumors that affect the distal extremities present different challenges and make multidisciplinary discussions desirable. METHODS/ RESULTS: We reported 3 patients who were approached with a conservative intention, after tumor board recomendation. The goals from the treatment performed were aesthetic and functional preservation, while enruring locoregional control. We had wound healing complications in 2 of the cases, requiring additional reconstruction measures. Patients are followed up for 24, 20 and 10 months; local control is 100%, and functional preservation is 100%. CONCLUSIONS: Despite being a small series, it was sufficient to illustrate successful multidisciplinary planning, generating a therapeutic result with improved quality of life for patients who had an initial indication for extremity amputation.
AIM: To show three patients with soft tissue sarcomas of distal extremities conservatively treated after tumor-board discussion, involving margin-free surgery, exclusive intraoperative radiotherapy, and immediate reconstruction. BACKGROUND: Current guidelines show clear and robust recommendations regarding the composition of the treatment of sarcomas of extremities. However, little evidence exists regarding the application of these treatments depending on the location of the primary neoplasia. Tumors that affect the distal extremities present different challenges and make multidisciplinary discussions desirable. METHODS/ RESULTS: We reported 3 patients who were approached with a conservative intention, after tumor board recomendation. The goals from the treatment performed were aesthetic and functional preservation, while enruring locoregional control. We had wound healing complications in 2 of the cases, requiring additional reconstruction measures. Patients are followed up for 24, 20 and 10 months; local control is 100%, and functional preservation is 100%. CONCLUSIONS: Despite being a small series, it was sufficient to illustrate successful multidisciplinary planning, generating a therapeutic result with improved quality of life for patients who had an initial indication for extremity amputation.
Authors: A O Naghavi; D C Fernandez; N Mesko; A Juloori; A Martinez; J G Scott; C Shah; L B Harrison Journal: Brachytherapy Date: 2017-03-23 Impact factor: 2.362
Authors: Reza Mirnezami; George J Chang; Prajnan Das; Kandiah Chandrakumaran; Paris Tekkis; Ara Darzi; Alexander H Mirnezami Journal: Surg Oncol Date: 2012-12-25 Impact factor: 3.279
Authors: John P Kirkpatrick; Scott G Soltys; Simon S Lo; Kathryn Beal; Dennis C Shrieve; Paul D Brown Journal: Neuro Oncol Date: 2017-04-01 Impact factor: 12.300
Authors: Z Vujaskovic; S M Gillette; B E Powers; S M LaRue; E L Gillette; T B Borak; R J Scott; T A Colacchio Journal: Radiother Oncol Date: 1994-02 Impact factor: 6.280
Authors: Samir Abdallah Hanna; Alfredo Carlos Simões Dornellas de Barros; Felipe Eduardo Martins de Andrade; Jose Luiz Barbosa Bevilacqua; José Roberto Morales Piato; Edilson Lopes Pelosi; Eduardo Martella; João Luis Fernandes da Silva; Heloisa de Andrade Carvalho Journal: Int J Radiat Oncol Biol Phys Date: 2014-07-08 Impact factor: 7.038
Authors: J LeVay; B O'Sullivan; C Catton; R Bell; V Fornasier; B Cummings; Y Hao; D Warr; I Quirt Journal: Int J Radiat Oncol Biol Phys Date: 1993-12-01 Impact factor: 7.038