Literature DB >> 33078267

Spinal fusion in pediatric patients with marfan syndrome: a nationwide assessment on short-term outcomes and readmission risk.

Michael W Fields1, Nathan J Lee2, Jacob R Ball2, Venkat Boddapati2, Justin Mathew2, Daniel Hong2, Josephine R Coury2, Zeeshan M Sardar2, Benjamin Roye3, Michael Vitale3, Lawrence G Lenke2.   

Abstract

PURPOSE: The purpose of this study was to utilize the National Readmission Database (NRD) to determine estimates for complication rates, 90-day readmission rates, and hospital costs associated with spinal fusion in pediatric patients with Marfan syndrome.
METHODS: The 2012-2015 NRD databases were queried for all pediatric (< 19 years old) patients diagnosed with Marfan syndrome undergoing spinal fusion surgery. The primary outcome variables in this study were index admission complications and 90-day readmissions.
RESULTS: A total of 249 patients with Marfan syndrome underwent spinal fusion surgery between 2012 and 2015 (mean age ± standard deviation at the time of surgery: 14 ± 2.0, 132 (53%) female). 25 (10.1%) were readmitted within 90 days of the index hospital discharge date. Overall, 59.7% of patients experienced at least one complication during the index admission. Unplanned 90-day readmission could be predicted by older age (odds ratio 2.3, 95% confidence interval 1.3-4.2, p = 0.006), Medicaid insurance status (56.0, 3.8-820.0, p = 0.003), and experiencing an inpatient medical complication (42.9, 4.6-398.7, p = 0.001). Patients were readmitted for wound dehiscence (8 patients, 3.2%), nervous system related complications (3 patients, 1.2%), and postoperative infectious related complications (4 patients, 1.6%).
CONCLUSION: This study is the first to demonstrate on a national level the complications and potential risk factors for 90-day hospital readmission for patients with Marfan syndrome undergoing spinal fusion. Patients with Marfan syndrome undergoing spinal fusion often present with multiple medical comorbidities that must be managed carefully perioperatively to reduce inpatient complications and early hospital readmissions.

Entities:  

Keywords:  Complicaitons; Marfan syndrome; Readmission; Scoliosis; Spinal fusion

Mesh:

Year:  2020        PMID: 33078267     DOI: 10.1007/s00586-020-06645-8

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  19 in total

1.  Rates and risk factors associated with unplanned hospital readmission after fusion for pediatric spinal deformity.

Authors:  Erika Roddy; Mohammad Diab
Journal:  Spine J       Date:  2016-10-17       Impact factor: 4.166

2.  A Comparative Analysis Among the SRS M&M, NIS, and KID Databases for the Adolescent Idiopathic Scoliosis.

Authors:  Nathan J Lee; Javier Z Guzman; Jun Kim; Branko Skovrlj; Christopher T Martin; Andrew J Pugely; Yubo Gao; John M Caridi; Sergio Mendoza-Lattes; Samuel K Cho
Journal:  Spine Deform       Date:  2016-10-26

3.  Readmissions, Observation, and the Hospital Readmissions Reduction Program.

Authors:  Rachael B Zuckerman; Steven H Sheingold; E John Orav; Joel Ruhter; Arnold M Epstein
Journal:  N Engl J Med       Date:  2016-02-24       Impact factor: 91.245

4.  Does Reoperation Risk Vary for Different Types of Pediatric Scoliosis?

Authors:  Justin C Paul; Baron S Lonner; Shaleen Vira; David Feldman; Thomas J Errico
Journal:  J Pediatr Orthop       Date:  2018-10       Impact factor: 2.324

Review 5.  The Marfan syndrome: diagnosis and management.

Authors:  R E Pyeritz; V A McKusick
Journal:  N Engl J Med       Date:  1979-04-05       Impact factor: 91.245

6.  Family studies of the Marfan syndrome.

Authors:  M K Keech; V E Wendt; R C Read; A R Bistue; F A Bianchi
Journal:  J Chronic Dis       Date:  1966-01

Review 7.  Spinal deformities in Marfan syndrome.

Authors:  Constantine A Demetracopoulos; Paul D Sponseller
Journal:  Orthop Clin North Am       Date:  2007-10       Impact factor: 2.472

8.  Minimally invasive repair of pectus excavatum in patients with Marfan syndrome and marfanoid features.

Authors:  Richard E Redlinger; Gregory D Rushing; Alan D Moskowitz; Robert E Kelly; Donald Nuss; Ann Kuhn; Robert J Obermeyer; Michael J Goretsky
Journal:  J Pediatr Surg       Date:  2010-01       Impact factor: 2.545

9.  Unplanned reoperation within 30 days of fusion surgery for spinal deformity.

Authors:  Zheng Li; Jianxiong Shen; Guixing Qiu; Haiquan Yu; Yipeng Wang; Jianguo Zhang; Hong Zhao; Yu Zhao; Shugang Li; Xisheng Weng; Jinqian Liang; Lijuan Zhao
Journal:  PLoS One       Date:  2014-03-04       Impact factor: 3.240

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