Literature DB >> 33067050

Outcome of an outpatient specialty clinic for chronic epipharyngitis.

Manabu Mogitate1, Yuko Sasaki2, Ayako Komiyama3.   

Abstract

OBJECTIVE: In Japan, chronic epipharyngitis became a subject of interest in the 1960s and is currently garnering renewed attention. Previous studies have focused only on the similarities between the immunological characteristics of the tonsil and epipharynx and reported the efficacy of epipharyngeal abrasive therapy (EAT) in patients with IgA nephropathy. However, endoscopic findings of chronic epipharyngitis have not yet been fully evaluated, and. this study aimed to elucidate those findings.
METHODS: The study period was from November 2016 to October 2017. Two hundred and twelve new patients visited the specialty outpatient clinic for EAT. Age distribution and mean age of patients, sex, chief complaint, diagnosis at other departments and outcomes were retrospectively reviewed based on medical records. Band-limited light endoscopy was performed, and the findings were videotaped in 102 of the 212 new patients, who underwent endoscopic EAT for the first time.
RESULTS: The study included 32 men and 70 women with a mean age of 46.0 years (range, 22-83 years). The most common complaint was postnasal drip (42 patients), followed by pharyngeal pain (12 patients), and throat discomfort (11 patients). The outcomes of 74 patients who continued treatment until the last session were; complete cure in 48.6% of cases, marked improvement in 21.6%, improvement in 16.2%, and no change in 13.5%. Band-limited light endoscopic findings included black spots (73%), granular changes (76%), vessel truncations (92%), crust/mucus adhesion (54%), adenoidal hypertrophy (31%) and tonsil cysts (7%). With regard to the appearance of the mucous membranes, 48% patients had an ivory-like-colored mucous membrane, 72% had a green vascular network, and 89% had a dark red to reddish-brown appearance. Six to nine months' EAT remarkably improved their symptoms with resolution of the endoscopic findings in 86% of the patients.
CONCLUSION: Nasal endoscopy using band-limited light is useful for diagnosis and management of chronic epipharyngitis. We believe that this study not only provides information to help the diagnosis of chronic epipharyngitis but also contributes to treat sick patients suffering from chronic epipharyngitis.
Copyright © 2020. Published by Elsevier B.V.

Entities:  

Keywords:  Band-limited light endoscope; Chronic epipharyngitis; Epipharyngeal Abrasive Therapy (EAT); Nasopharynx

Year:  2020        PMID: 33067050     DOI: 10.1016/j.anl.2020.09.019

Source DB:  PubMed          Journal:  Auris Nasus Larynx        ISSN: 0385-8146            Impact factor:   1.863


  5 in total

1.  Epipharyngeal Abrasive Therapy Down-regulates the Expression of SARS-CoV-2 Entry Factors ACE2 and TMPRSS2.

Authors:  Kensuke Nishi; Shohei Yoshimoto; Soichiro Nishi; Toshiyuki Tsunoda; Jun Ohno; Michinobu Yoshimura; Kenji Hiromatsu; Takafumi Yamano
Journal:  In Vivo       Date:  2022 Jan-Feb       Impact factor: 2.155

2.  Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.

Authors:  Kensuke Nishi; Shohei Yoshimoto; Soichiro Nishi; Tatsuro Nishi; Ryushiro Nishi; Toshiyuki Tsunoda; Hiromitsu Morita; Hiroaki Tanaka; Osamu Hotta; Susumu Yasumasu; Kenji Hiromatsu; Senji Shirasawa; Takashi Nakagawa; Takafumi Yamano
Journal:  In Vivo       Date:  2022 Sep-Oct       Impact factor: 2.406

3.  Epipharyngeal Abrasive Therapy (EAT) Has Potential as a Novel Method for Long COVID Treatment.

Authors:  Kazuaki Imai; Takafumi Yamano; Soichiro Nishi; Ryushiro Nishi; Tatsuro Nishi; Hiroaki Tanaka; Toshiyuki Tsunoda; Shohei Yoshimoto; Ayaki Tanaka; Kenji Hiromatsu; Senji Shirasawa; Takashi Nakagawa; Kensuke Nishi
Journal:  Viruses       Date:  2022-04-27       Impact factor: 5.818

4.  Epipharyngeal Abrasive Therapy (EAT) Reduces the mRNA Expression of Major Proinflammatory Cytokine IL-6 in Chronic Epipharyngitis.

Authors:  Kensuke Nishi; Shohei Yoshimoto; Soichiro Nishi; Tatsuro Nishi; Ryushiro Nishi; Takayuki Tanaka; Toshiyuki Tsunoda; Kazuaki Imai; Hiroaki Tanaka; Osamu Hotta; Ayaki Tanaka; Kenji Hiromatsu; Senji Shirasawa; Takashi Nakagawa; Takafumi Yamano
Journal:  Int J Mol Sci       Date:  2022-08-16       Impact factor: 6.208

Review 5.  Title IgA Nephropathy and Oral Bacterial Species Related to Dental Caries and Periodontitis.

Authors:  Yasuyuki Nagasawa; Taro Misaki; Seigo Ito; Shuhei Naka; Kaoruko Wato; Ryota Nomura; Michiyo Matsumoto-Nakano; Kazuhiko Nakano
Journal:  Int J Mol Sci       Date:  2022-01-10       Impact factor: 5.923

  5 in total

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