Literature DB >> 33057893

PrEP Uptake and Discontinuation Among a U.S. National Sample of Transgender Men and Women.

Meagan Zarwell1, Steven A John2, Drew Westmoreland3, Chloe Mirzayi3, David W Pantalone4,5, Sarit Golub6, Denis Nash3, Christian Grov7.   

Abstract

Pre-exposure prophylaxis (PrEP) has revolutionized HIV prevention efforts by effectively preventing the sexual transmission of HIV infection. Few studies have examined PrEP uptake and discontinuation among transgender individuals who are underserved in HIV prevention efforts. An online U.S. nationwide survey screened 294 HIV-negative transgender people for participation in a larger cohort study. We analyzed associations between demographic characteristics and PrEP use and discontinuation. We conducted thematic analyses of open-ended responses to identify reasons for PrEP discontinuation. Fifty-one participants (17.4%) reported ever receiving a PrEP prescription. Transgender men reported higher PrEP use than transgender women (χ2 = 18.06; p < 0.0001). PrEP discontinuation was reported by 49.0% of individuals who reported PrEP use. Reasons for PrEP discontinuation were related to side effects, insurance coverage, relationship status, and access to providers. HIV prevention efforts to increase PrEP should include mechanisms for PrEP uptake and re-initiation among transgender individuals.

Entities:  

Keywords:  Discontinuation; HIV prevention; PrEP; Transgender; Uptake

Mesh：

Substances：

Year:  2020        PMID： 33057893      PMCID： PMC7979462          DOI： 10.1007/s10461-020-03064-0

Source DB:  PubMed          Journal:  AIDS Behav        ISSN： 1090-7165


  25 in total

1.  Recruiting vulnerable populations to participate in HIV prevention research: findings from the Together 5000 cohort study.

Authors:  Christian Grov; Drew A Westmoreland; Pedro B Carneiro; Matthew Stief; Caitlin MacCrate; Chloe Mirzayi; David W Pantalone; Viraj V Patel; Denis Nash
Journal:  Ann Epidemiol       Date:  2019-05-16       Impact factor: 3.797

2.  PrEP Discontinuation and Prevention-Effective Adherence: Experiences of PrEP Users in Ugandan HIV Serodiscordant Couples.

Authors:  Hannah N Gilbert; Monique A Wyatt; Emily E Pisarski; Timothy R Muwonge; Renee Heffron; Elly T Katabira; Connie L Celum; Jared M Baeten; Jessica E Haberer; Norma C Ware
Journal:  J Acquir Immune Defic Syndr       Date:  2019-11-01       Impact factor: 3.731

3.  Barriers to Gender-Affirming Care for Transgender and Gender Nonconforming Individuals.

Authors:  Jae A Puckett; Peter Cleary; Kinton Rossman; Michael E Newcomb; Brian Mustanski
Journal:  Sex Res Social Policy       Date:  2017-08-04

4.  A Multi-US City Assessment of Awareness and Uptake of Pre-exposure Prophylaxis (PrEP) for HIV Prevention Among Black Men and Transgender Women Who Have Sex with Men.

Authors:  Lisa A Eaton; Derrick D Matthews; Daniel D Driffin; Leigh Bukowski; Patrick A Wilson; Ron D Stall
Journal:  Prev Sci       Date:  2017-07

5.  Racial/ethnic and HIV risk category disparities in preexposure prophylaxis discontinuation among patients in publicly funded primary care clinics.

Authors:  Hyman M Scott; Matthew Spinelli; Eric Vittinghoff; Alicia Morehead-Gee; Anne Hirozawa; Catherine James; Hali Hammer; Albert Liu; Monica Gandhi; Susan Buchbinder
Journal:  AIDS       Date:  2019-11-15       Impact factor: 4.177

Review 6.  Worldwide burden of HIV in transgender women: a systematic review and meta-analysis.

Authors:  Stefan D Baral; Tonia Poteat; Susanne Strömdahl; Andrea L Wirtz; Thomas E Guadamuz; Chris Beyrer
Journal:  Lancet Infect Dis       Date:  2012-12-21       Impact factor: 25.071

7.  Lifetime risk factors for HIV/sexually transmitted infections among male-to-female transgender persons.

Authors:  Larry Nuttbrock; Sel Hwahng; Walter Bockting; Andrew Rosenblum; Mona Mason; Monica Macri; Jeffrey Becker
Journal:  J Acquir Immune Defic Syndr       Date:  2009-11-01       Impact factor: 3.731

8.  Acceptability of Antiretroviral Pre-exposure Prophylaxis from a Cohort of Sexually Experienced Young Transgender Women in Two U.S. Cities.

Authors:  Arjee J Restar; Lisa Kuhns; Sari L Reisner; Adedotun Ogunbajo; Robert Garofalo; Matthew J Mimiaga
Journal:  AIDS Behav       Date:  2018-11

9.  HIV Testing Among Transgender Women and Men - 27 States and Guam, 2014-2015.

Authors:  Marc A Pitasi; Emeka Oraka; Hollie Clark; Machell Town; Elizabeth A DiNenno
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2017-08-25       Impact factor: 17.586

10.  HIV Testing and PrEP Use in a National Probability Sample of Sexually Active Transgender People in the United States.

Authors:  Jae M Sevelius; Tonia Poteat; Winston E Luhur; Sari L Reisner; Ilan H Meyer
Journal:  J Acquir Immune Defic Syndr       Date:  2020-08-15       Impact factor: 3.771
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  6 in total

1.  High Awareness But Low Uptake of Pre-Exposure Prophylaxis in a Community Sample of Trans Masculine Adults in Massachusetts.

Authors:  Jaclyn M W Hughto; Yohansa Fernández; Arjee Restar; Lynne B Klasko-Foster; Madeline B Deutsch; Sarah Peitzmeier; Jennifer Potter; Matthew J Mimiaga; Sari L Reisner
Journal:  AIDS Patient Care STDS       Date:  2022-06-21       Impact factor: 5.944

2.  Association of Race and Other Social Determinants of Health With HIV Pre-Exposure Prophylaxis Use: A County-Level Analysis Using the PrEP-to-Need Ratio.

Authors:  Ryan Doherty; Jennifer L Walsh; Katherine G Quinn; Steven A John
Journal:  AIDS Educ Prev       Date:  2022-06

3.  Intersectional Discrimination and PrEP uSe Among Young Black Sexual Minority Individuals: The Importance of Black LGBTQ Communities and Social Support.

Authors:  Katherine G Quinn; Julia Dickson-Gomez; Amber Craig; Steven A John; Jennifer L Walsh
Journal:  AIDS Behav       Date:  2022-07-05

4.  Uptake, Retention, and Adherence to Pre-exposure Prophylaxis (PrEP) in TRIUMPH: A Peer-Led PrEP Demonstration Project for Transgender Communities in Oakland and Sacramento, California.

Authors:  Jae M Sevelius; David V Glidden; Madeline Deutsch; Layla Welborn; Alejandro Contreras; Arianna Salinas; Luz Venegas; Robert M Grant
Journal:  J Acquir Immune Defic Syndr       Date:  2021-12-15       Impact factor: 3.771

5.  COVID-19-Related Disruptions to HIV Testing and Prevention Among Young Sexual Minority Men 17-24 Years Old: A Qualitative Study Using Synchronous Online Focus Groups, April-September 2020.

Authors:  Juan Pablo Zapata; Madeline Dang; Katherine G Quinn; Keith J Horvath; Rob Stephenson; Julia Dickson-Gomez; Steven A John
Journal:  Arch Sex Behav       Date:  2021-11-12

6.  Understanding Retention in Pre-Exposure Prophylaxis Care in the South: Insights from an Academic HIV Prevention Clinic.

Authors:  Charles M Burns; Monica Borges; Justin Frye; Kathryn Keicher; Scotty Elliott; Sheila Schwartz; Kenneth Shipp; Nwora Lance Okeke; Mehri S McKellar
Journal:  AIDS Res Hum Retroviruses       Date:  2022-04       Impact factor: 2.205
  6 in total

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