Literature DB >> 330504

Origin and direction of replication of the drug resistance plasmid R100.1 and of a resistance transfer factor derivative in synchronized cultures.

L Silver, M Chandler, E B de la Tour, L Caro.   

Abstract

The origin and direction of replication of the resistance plasmid R100.1 and its resistance transfer factor derivative, pAR132, were studied by electron microscopy autoradiography of partially denatured molecules and partial denaturation mapping of replicative intermediates. Results of these studies indicate the existence of an origin of replication at 8.8 kilobases on the R100 map. Replication from this origin in cultures synchronized for initiation of replication is predominantly unidirectional in a single direction.

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Year:  1977        PMID: 330504      PMCID: PMC235551          DOI: 10.1128/jb.131.3.929-942.1977

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  35 in total

1.  Infective heredity of multiple drug resistance in bacteria.

Authors:  T WATANABE
Journal:  Bacteriol Rev       Date:  1963-03

2.  Resistance transfer agents in Shigella.

Authors:  R NAKAYA; A NAKAMURA; Y MURATA
Journal:  Biochem Biophys Res Commun       Date:  1960-12       Impact factor: 3.575

3.  Nucleotide sequence of bacteriophage phi X174 DNA.

Authors:  F Sanger; G M Air; B G Barrell; N L Brown; A R Coulson; C A Fiddes; C A Hutchison; P M Slocombe; M Smith
Journal:  Nature       Date:  1977-02-24       Impact factor: 49.962

4.  Suppression of an Escherichia coli dnaA mutation by the integrated R factor R100.1: generation of small plasmids after integration.

Authors:  M Chandler; L Silver; J Frey; L Caro
Journal:  J Bacteriol       Date:  1977-04       Impact factor: 3.490

5.  More precise mapping of the replication origin in Escherichia coli K-12.

Authors:  J Louarn; M Funderburgh; R E Bird
Journal:  J Bacteriol       Date:  1974-10       Impact factor: 3.490

6.  Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors.

Authors:  P A Sharp; S N Cohen; N Davidson
Journal:  J Mol Biol       Date:  1973-04-05       Impact factor: 5.469

7.  Molecular nature of the drug-resistance factors of the Enterobacteriaceae.

Authors:  R Rownd; R Nakaya; A Nakamura
Journal:  J Mol Biol       Date:  1966-06       Impact factor: 5.469

8.  Non-chromosomal antibiotic resistance in bacteria. II. Molecular nature of R-factors isolated from Proteus mirabilis and Escherichia coli.

Authors:  S N Cohen; C A Miller
Journal:  J Mol Biol       Date:  1970-06-28       Impact factor: 5.469

9.  Dissociation and reassociation of RTF and r-determinants of the R-factor NR1 in Proteus mirabilis.

Authors:  R Rownd; S Mickel
Journal:  Nat New Biol       Date:  1971-11-10

10.  High-resolution autoradiography. I. Methods.

Authors:  L G CARO; R P VAN TUBERGEN; J A KOLB
Journal:  J Cell Biol       Date:  1962-11       Impact factor: 10.539

View more
  29 in total

1.  Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center.

Authors:  Neil Woodford; Philip M Tierno; Katherine Young; Luke Tysall; Marie-France I Palepou; Elaina Ward; Ronald E Painter; Deborah F Suber; Daniel Shungu; Lynn L Silver; Kenneth Inglima; John Kornblum; David M Livermore
Journal:  Antimicrob Agents Chemother       Date:  2004-12       Impact factor: 5.191

2.  Lambda transducing phages derived from a FinO- R100::lambda cointegrate plasmid: proteins encoded by the R100 replication/incompatibility region and the antibiotic resistance determinant.

Authors:  W B Dempsey; S A McIntire
Journal:  Mol Gen Genet       Date:  1979-11

Review 3.  Genetic and physical map of plasmid NR1: comparison with other IncFII antibiotic resistance plasmids.

Authors:  D D Womble; R H Rownd
Journal:  Microbiol Rev       Date:  1988-12

4.  Genetic analysis of the inter-relationship between plasmid replication and incompatibility.

Authors:  P A Meacock; S N Cohen
Journal:  Mol Gen Genet       Date:  1979-07-13

5.  Structural and functional analysis of cloned DNA segments containing the replication and incompatibility regions of a miniplasmid derived from a copy number mutant of NR1.

Authors:  D P Taylor; S N Cohen
Journal:  J Bacteriol       Date:  1979-01       Impact factor: 3.490

6.  Isolation and characterization of the minimal fragment required for autonomous replication ("basic replicon") of a copy mutant (pKN102) of the antibiotic resistance factor R1.

Authors:  R Kollek; W Oertel; W Goebel
Journal:  Mol Gen Genet       Date:  1978-06-01

7.  Suppression of Escherichia coli dnaA46 mutations by integration of plasmid R100.1. derivatives: constraints imposed by the replication terminus.

Authors:  J Louarn; J Patte; J M Louarn
Journal:  J Bacteriol       Date:  1982-08       Impact factor: 3.490

8.  Direction of bacteriophage lambda DNA replication in a thymine requiring Escherichia coli K-12 strain. Effect of thymidine concentration.

Authors:  M S Valenzuela; R B Inman
Journal:  Nucleic Acids Res       Date:  1981-12-21       Impact factor: 16.971

9.  The involvement of host replication proteins and of specific origin sequences in the in vitro replication of miniplasmid R1 DNA.

Authors:  S Ortega; E Lanka; R Diaz
Journal:  Nucleic Acids Res       Date:  1986-06-25       Impact factor: 16.971

10.  Plasmid replication functions: two distinct segments of plasmid R1, RepA and RepD, express incompatibility and are capable of autonomous replication.

Authors:  H Danbara; J K Timmis; R Lurz; K N Timmis
Journal:  J Bacteriol       Date:  1980-12       Impact factor: 3.490

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