| Literature DB >> 330504 |
L Silver, M Chandler, E B de la Tour, L Caro.
Abstract
The origin and direction of replication of the resistance plasmid R100.1 and its resistance transfer factor derivative, pAR132, were studied by electron microscopy autoradiography of partially denatured molecules and partial denaturation mapping of replicative intermediates. Results of these studies indicate the existence of an origin of replication at 8.8 kilobases on the R100 map. Replication from this origin in cultures synchronized for initiation of replication is predominantly unidirectional in a single direction.Entities:
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Year: 1977 PMID: 330504 PMCID: PMC235551 DOI: 10.1128/jb.131.3.929-942.1977
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490