Literature DB >> 33044687

DOT Diary: Developing a Novel Mobile App Using Artificial Intelligence and an Electronic Sexual Diary to Measure and Support PrEP Adherence Among Young Men Who Have Sex with Men.

Albert Y Liu1,2, Nicole D Laborde3, Kenneth Coleman4, Eric Vittinghoff5, Rafael Gonzalez4, Gretchen Wilde6, Annie L Thorne6, Ed Ikeguchi7, Laura Shafner7, Lauren Sunshine7, Ariane van der Straten8,9, Aaron J Siegler6, Susan Buchbinder4,8,5.   

Abstract

Young men who have sex with men (YMSM) are highly vulnerable to HIV. While pre-exposure prophylaxis (PrEP) has demonstrated effectiveness, adherence has been low among YMSM and difficult to measure accurately. In collaboration with a healthcare company, we configured an automated directly-observed therapy (aDOT) platform for monitoring and supporting PrEP use. Based on interest expressed in focus groups among 54 YMSM, we combined aDOT with an electronic sexual diary to provide feedback on level of protection during sex and to motivate app use. In an 8-week optimization pilot with 20 YMSM in San Francisco and Atlanta, the app was found to be highly acceptable, with median System Usability Scale scores in the "excellent" range (80/100). App use was high, with median PrEP adherence of 91% based on aDOT-confirmed dosing. Most (84%) participants reported the app helped with taking PrEP. These promising findings support further evaluation of DOT Diary in future effectiveness studies.

Entities:  

Keywords:  Adherence; Artificial intelligence; HIV; Mobile health; Pre-exposure prophylaxis

Mesh：

Year:  2020        PMID： 33044687      PMCID： PMC7979437          DOI： 10.1007/s10461-020-03054-2

Source DB:  PubMed          Journal:  AIDS Behav        ISSN： 1090-7165


  58 in total

1.  Prototype of a breath-based analysis system for medication compliance monitoring.

Authors:  Vikas V Meka; Brent J Lutz; Richard J Melker; Neil R Euliano
Journal:  J Breath Res       Date:  2007-12-06       Impact factor: 3.262

Review 2.  Self-management: a comprehensive approach to management of chronic conditions.

Authors:  Patricia A Grady; Lisa Lucio Gough
Journal:  Am J Public Health       Date:  2014-06-12       Impact factor: 9.308

3.  Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana.

Authors:  Michael C Thigpen; Poloko M Kebaabetswe; Lynn A Paxton; Dawn K Smith; Charles E Rose; Tebogo M Segolodi; Faith L Henderson; Sonal R Pathak; Fatma A Soud; Kata L Chillag; Rodreck Mutanhaurwa; Lovemore Ian Chirwa; Michael Kasonde; Daniel Abebe; Evans Buliva; Roman J Gvetadze; Sandra Johnson; Thom Sukalac; Vasavi T Thomas; Clyde Hart; Jeffrey A Johnson; C Kevin Malotte; Craig W Hendrix; John T Brooks
Journal:  N Engl J Med       Date:  2012-07-11       Impact factor: 91.245

4.  Using Artificial Intelligence to Reduce the Risk of Nonadherence in Patients on Anticoagulation Therapy.

Authors:  Daniel L Labovitz; Laura Shafner; Morayma Reyes Gil; Deepti Virmani; Adam Hanina
Journal:  Stroke       Date:  2017-04-06       Impact factor: 7.914

5.  Tenofovir-based preexposure prophylaxis for HIV infection among African women.

Authors:  Jeanne M Marrazzo; Gita Ramjee; Barbra A Richardson; Kailazarid Gomez; Nyaradzo Mgodi; Gonasagrie Nair; Thesla Palanee; Clemensia Nakabiito; Ariane van der Straten; Lisa Noguchi; Craig W Hendrix; James Y Dai; Shayhana Ganesh; Baningi Mkhize; Marthinette Taljaard; Urvi M Parikh; Jeanna Piper; Benoît Mâsse; Cynthia Grossman; James Rooney; Jill L Schwartz; Heather Watts; Mark A Marzinke; Sharon L Hillier; Ian M McGowan; Z Mike Chirenje
Journal:  N Engl J Med       Date:  2015-02-05       Impact factor: 91.245

6.  Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial.

Authors:  Kachit Choopanya; Michael Martin; Pravan Suntharasamai; Udomsak Sangkum; Philip A Mock; Manoj Leethochawalit; Sithisat Chiamwongpaet; Praphan Kitisin; Pitinan Natrujirote; Somyot Kittimunkong; Rutt Chuachoowong; Roman J Gvetadze; Janet M McNicholl; Lynn A Paxton; Marcel E Curlin; Craig W Hendrix; Suphak Vanichseni
Journal:  Lancet       Date:  2013-06-13       Impact factor: 79.321

7.  The acceptability and feasibility of an HIV preexposure prophylaxis (PrEP) trial with young men who have sex with men.

Authors:  Sybil G Hosek; George Siberry; Margo Bell; Michelle Lally; Bill Kapogiannis; Keith Green; M Isabel Fernandez; Brandy Rutledge; Jaime Martinez; Robert Garofalo; Craig M Wilson
Journal:  J Acquir Immune Defic Syndr       Date:  2013-04-01       Impact factor: 3.731

8.  The feasibility of modified directly observed therapy for HIV-seropositive African American substance users.

Authors:  Mindy Ma; Billy R Brown; Melissa Coleman; Jeffrey L Kibler; Helen Loewenthal; Jennifer A Mitty
Journal:  AIDS Patient Care STDS       Date:  2008-02       Impact factor: 5.078

9.  Where are the young men in HIV prevention efforts? Comments on HIV prevention programs and research from young men who sex with men in Los Angeles county.

Authors:  Ian W Holloway; Julie A Cederbaum; Antonette Ajayi; Steven Shoptaw
Journal:  J Prim Prev       Date:  2012-12

10.  Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial.

Authors:  Sheena McCormack; David T Dunn; Monica Desai; David I Dolling; Mitzy Gafos; Richard Gilson; Ann K Sullivan; Amanda Clarke; Iain Reeves; Gabriel Schembri; Nicola Mackie; Christine Bowman; Charles J Lacey; Vanessa Apea; Michael Brady; Julie Fox; Stephen Taylor; Simone Antonucci; Saye H Khoo; James Rooney; Anthony Nardone; Martin Fisher; Alan McOwan; Andrew N Phillips; Anne M Johnson; Brian Gazzard; Owen N Gill
Journal:  Lancet       Date:  2015-09-09       Impact factor: 79.321
View more
  13 in total

Review 1.  Digital directly observed therapy to monitor adherence to medications: a scoping review.

Authors:  Marie C D Stoner; Allysha C Maragh-Bass; Adam C Sukhija-Cohen; Parya Saberi
Journal:  HIV Res Clin Pract       Date:  2022-07-18

2.  Randomized Controlled Trial of Automated Directly Observed Therapy for Measurement and Support of PrEP Adherence Among Young Men Who have Sex with Men.

Authors:  Susan P Buchbinder; Aaron J Siegler; Kenneth Coleman; Eric Vittinghoff; Gretchen Wilde; Annie Lockard; Hyman Scott; Peter L Anderson; Nicole Laborde; Ariane van der Straten; Richard H Christie; Michelle Marlborough; Albert Y Liu
Journal:  AIDS Behav       Date:  2022-08-19

Review 3.  The Potential of Telecommunication Technology to Address Racial/Ethnic Disparities in HIV PrEP Awareness, Uptake, Adherence, and Persistence in Care: A Review.

Authors:  Kimberly N Evans; Rashida Hassan; Ashley Townes; Kate Buchacz; Dawn K Smith
Journal:  AIDS Behav       Date:  2022-05-25

4.  Potential Role of Conversational Agents in Encouraging PrEP Uptake.

Authors:  Maryam Hassani; Sean D Young
Journal:  J Behav Health Serv Res       Date:  2022-05-05       Impact factor: 1.475

5.  Usability and effectiveness of adherence monitoring of a mobile app designed to monitor and improve adherence to event-driven and daily HIV pre-exposure prophylaxis among men who have sex with men in Taiwan.

Authors:  Huei-Jiuan Wu; Yi-Fang Yu; Stephane Wen-Wei Ku; Yuan-Chi Tseng; Chien-Wen Yuan; Chia-Wen Li; Po-Hsien Huang; Nai-Ying Ko; Peter L Anderson; Carol Strong
Journal:  Digit Health       Date:  2022-05-22

6.  Developing Culturally Tailored mHealth Tools to Address Sexual and Reproductive Health Outcomes Among Black and Latina Women: A Systematic Review.

Authors:  Rasheeta Chandler; Dominique Guillaume; Andrea Parker; Jessica Wells; Natalie D Hernandez
Journal:  Health Promot Pract       Date:  2021-03-26

7.  Factors Influencing the Intention of MSM to Use the PrEP Intelligent Reminder System.

Authors:  Yingjie Ma; Xiaoni Zhong; Bing Lin; Wei He
Journal:  Risk Manag Healthc Policy       Date:  2021-11-24

8.  Effect Evaluation of Artificial Intelligence-Based Electronic Health PDCA Nursing Model in the Treatment of Mycoplasma Pneumonia in Children.

Authors:  Yan Zhao
Journal:  J Healthc Eng       Date:  2022-03-11       Impact factor: 2.682

Review 9.  Analytical mapping of information and communication technology in emerging infectious diseases using CiteSpace.

Authors:  Sandeep Kumar Sood; Keshav Singh Rawat; Dheeraj Kumar
Journal:  Telemat Inform       Date:  2022-03-08

10.  Condomless Anal Sex Associated With Heterogeneous Profiles Of HIV Pre-Exposure Prophylaxis Use and Sexual Activities Among Men Who Have Sex With Men: A Latent Class Analysis Using Sex Diary Data on a Mobile App.

Authors:  Yi-Fang Yu; Huei-Jiuan Wu; Stephane Wen-Wei Ku; Po-Hsien Huang; Chia-Wen Li; Poyao Huang; Carol Strong
Journal:  J Med Internet Res       Date:  2021-12-23       Impact factor: 5.428
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.