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Literature DB >> 3304207

Initiation and promotion in hepatocarcinogenesis.

Abstract

Initiation and promotion have been recognized as essential parts of the multi-stage concept of chemical carcinogenesis. In the liver, initiation by genotoxic carcinogens results in appearance of foci of phenotypically altered hepatocytes. Accelerated growth and phenotypic changes of these foci during tumor promotion by phenobarbital are described, and possible mechanisms of initiation and promotion considered.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1987 PMID： 3304207 DOI： 10.1007/BF00296976

Source DB: PubMed Journal: Arch Toxicol ISSN： 0340-5761 Impact factor: 5.153

17 in total

1. Induction of liver growth by xenobiotic compounds and other stimuli.

Authors: R Schulte-Hermann
Journal: CRC Crit Rev Toxicol Date: 1974-09

2. The function and mechanism of promoters of carcinogenesis.

Authors: R K Boutwell
Journal: CRC Crit Rev Toxicol Date: 1974-01

Review 3. Tumor promotion in the liver.

Authors: R Schulte-Hermann
Journal: Arch Toxicol Date: 1985-08 Impact factor: 5.153

Review 4. The sequential analysis of cancer development.

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Journal: Adv Cancer Res Date: 1980 Impact factor: 6.242

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Authors: E Hecker
Journal: Naturwissenschaften Date: 1978-12

6. Inhibitory effect of nafenopin upon the development of diethylnitrosamine-induced enzyme-altered foci within the rat liver.

Authors: W Stäubli; P Bentley; F Bieri; E Fröhlich; F Waechter
Journal: Carcinogenesis Date: 1984-01 Impact factor: 4.944

7. Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters.

Authors: W Bursch; B Lauer; I Timmermann-Trosiener; G Barthel; J Schuppler; R Schulte-Hermann
Journal: Carcinogenesis Date: 1984-04 Impact factor: 4.944

8. Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.

Authors: H Zarbl; S Sukumar; A V Arthur; D Martin-Zanca; M Barbacid
Journal: Nature Date: 1985 May 30-Jun 5 Impact factor: 49.962

9. Hepatocellular glycogenosis and related pattern of enzymatic changes during hepatocarcinogenesis.

Authors: P Bannasch; H J Hacker; F Klimek; D Mayer
Journal: Adv Enzyme Regul Date: 1984

10. Pyruvate kinase isoenzymes in altered foci and carcinoma of rat liver.

Authors: M Reinacher; E Eigenbrodt; U Gerbracht; G Zenk; I Timmermann-Trosiener; P Bentley; F Waechter; R Schulte-Hermann
Journal: Carcinogenesis Date: 1986-08 Impact factor: 4.944

4 in total

1. Effect of nuclear localization and hydrodynamic delivery-induced cell division on phiC31 integrase activity.

Authors: L E Woodard; R T Hillman; A Keravala; S Lee; M P Calos
Journal: Gene Ther Date: 2009-10-22 Impact factor: 5.250

2. Selective induction of DNA synthesis in mouse preneoplastic and neoplastic hepatic lesions after exposure to phenobarbital.

Authors: J E Klaunig
Journal: Environ Health Perspect Date: 1993-12 Impact factor: 9.031

3. Minimal role of enhanced cell proliferation in skin tumor promotion by mirex: a nonphorbol ester-type promoter.

Authors: S A Meyer; G J Moser; N A Monteiro-Riviere; R C Smart
Journal: Environ Health Perspect Date: 1993-12 Impact factor: 9.031

4. Biphasic modifying effect of indole-3-carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats.

Authors: D J Kim; K K Lee; B S Han; B Ahn; J H Bae; J J Jang
Journal: Jpn J Cancer Res Date: 1994-06

4 in total