| Literature DB >> 33036718 |
Gianluca Caiazzo1, Rita Leonarda Musci2, Lara Frediani3, Julia Umińska4, Wojciech Wanha5, Krzysztof J Filipiak6, Jacek Kubica4, Eliano Pio Navarese7.
Abstract
Primary percutaneous coronary intervention is the preferred reperfusion strategy for the management of acute ST-segment elevation myocardial infarction. No reflow is characterized by the inadequate myocardial perfusion of a given segment without angiographic evidence of persistent mechanical obstruction of epicardial vessels. Both pharmacologic and device-based strategies have been tested to resolve coronary no reflow. This article provides an updated overview of the no-reflow phenomenon, discussing clinical evidence and ongoing investigations of existing and novel therapeutic strategies to counteract it.Entities:
Keywords: Microvascular obstruction; No-reflow; Primary PCI
Mesh:
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Year: 2020 PMID: 33036718 DOI: 10.1016/j.ccl.2020.07.001
Source DB: PubMed Journal: Cardiol Clin ISSN: 0733-8651 Impact factor: 2.213