Heavy metals in indoor dust: Spatial distribution, influencing factors, and potential health risks.

Given the large proportion of time that people spend indoors, the potential health risks posed by heavy metals in the indoor environment deserve greater attention. A global-scale assessment of heavy metal contamination in indoor dust was conducted in this study based on >127 articles published between 1985 and 2019. The pollution levels, spatio-temporal variations, sources, bioaccessibilities, influencing factors, and health risks of heavy metals associated with indoor dust were analyzed. Children's blood lead levels (BLLs) were also estimated using the integrated exposure uptake biokinetic model. The results indicated that the median concentrations of Cu and Zn in 71.9% and 71.0% of the study sites surpassed the corresponding permissible limits, 100 and 300 mg/kg, respectively; thus, their control should be given priority. Heavy metal concentrations in indoor dust from different areas of the world varied greatly, which was closely associated with the type of local human activities, such as mining, melting, e-waste recycling and Pb-related industries. The bioaccessibilities of some key elements, e.g., Pb, Cd, Cu, and Zn, in household dust were high. The levels of heavy metals in indoor dust were mainly affected by a combination of outdoor and indoor sources and related critical factors, and future studies should focus on quantifying the contributions of different sources. Based on the health risk assessment, dust Pb exposure is a major health concern in e-waste recycling areas, which warrants greater attention. 49.8%, 36.8% and 14.4% of study sites showed BLLs exceeding 35 μg/L (threshold limit in Germany), 50 μg/L (threshold limit in the USA), or 100 μg/L (threshold limit in China), respectively. Finally, Pb exposure from indoor dust represents a major contributor to children's blood Pb poisoning in many developing countries. This study details the overall heavy metal contamination status of indoor dust and provides insights for policymakers with respect to pollution prevention measures.