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Literature DB >> 32999862

Glioblastoma radiosensitization by pimozide.

Barbara H Rath¹, Kevin Camphausen¹, Philip J Tofilon¹.

Abstract

Entities: CellLine Chemical Disease Gene Species

Year: 2016 PMID： 32999862 PMCID： PMC7523920 DOI： 10.21037/tcr.2016.11.17

Source DB: PubMed Journal: Transl Cancer Res ISSN： 2218-676X Impact factor: 1.241

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24 in total

1. Selective and cell-active inhibitors of the USP1/ UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells.

Authors: Junjun Chen; Thomas S Dexheimer; Yongxing Ai; Qin Liang; Mark A Villamil; James Inglese; David J Maloney; Ajit Jadhav; Anton Simeonov; Zhihao Zhuang
Journal: Chem Biol Date: 2011-11-23

2. USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma.

Authors: Samuel A Williams; Heather L Maecker; Dorothy M French; Jinfeng Liu; Andrew Gregg; Leah B Silverstein; Tim C Cao; Richard A D Carano; Vishva M Dixit
Journal: Cell Date: 2011-09-16 Impact factor: 41.582

3. Cytotoxic effects of antipsychotic drugs implicate cholesterol homeostasis as a novel chemotherapeutic target.

Authors: Erik D Wiklund; Vibeke S Catts; Stanley V Catts; Teng Fong Ng; Noel J Whitaker; Andrew J Brown; Louise H Lutze-Mann
Journal: Int J Cancer Date: 2010-01-01 Impact factor: 7.396

4. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines.

Authors: Jeongwu Lee; Svetlana Kotliarova; Yuri Kotliarov; Aiguo Li; Qin Su; Nicholas M Donin; Sandra Pastorino; Benjamin W Purow; Neil Christopher; Wei Zhang; John K Park; Howard A Fine
Journal: Cancer Cell Date: 2006-05 Impact factor: 31.743

5. Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.

Authors: Jung Min Kim; Kalindi Parmar; Min Huang; David M Weinstock; Carrie Ann Ruit; Jeffrey L Kutok; Alan D D'Andrea
Journal: Dev Cell Date: 2009-02 Impact factor: 12.270

Review 6. Role of Deubiquitinating Enzymes in DNA Repair.

Authors: Younghoon Kee; Tony T Huang
Journal: Mol Cell Biol Date: 2015-12-07 Impact factor: 4.272

7. Identification of a cancer stem cell in human brain tumors.

Authors: Sheila K Singh; Ian D Clarke; Mizuhiko Terasaki; Victoria E Bonn; Cynthia Hawkins; Jeremy Squire; Peter B Dirks
Journal: Cancer Res Date: 2003-09-15 Impact factor: 12.701

Review 8. USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy.

Authors: Iraia García-Santisteban; Godefridus J Peters; Elisa Giovannetti; Jose Antonio Rodríguez
Journal: Mol Cancer Date: 2013-08-10 Impact factor: 27.401

Glioblastoma radiosensitization by pimozide.

1. Selective and cell-active inhibitors of the USP1/ UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells.

2. USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma.

3. Cytotoxic effects of antipsychotic drugs implicate cholesterol homeostasis as a novel chemotherapeutic target.

4. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines.

5. Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.

Review 6. Role of Deubiquitinating Enzymes in DNA Repair.

7. Identification of a cancer stem cell in human brain tumors.

Review 8. USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy.

9. The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma.

10. Deubiquitination of FANCD2 is required for DNA crosslink repair.

Review 1. Molecular Pathways and Genomic Landscape of Glioblastoma Stem Cells: Opportunities for Targeted Therapy.

Review 2. Dysregulation of the Ubiquitin Proteasome System in Human Malignancies: A Window for Therapeutic Intervention.