Carolina L Haass-Koffler1,2, Rachel D Souza2, James P Wilmott3, Elizabeth R Aston2, Joo-Hyun Song3. 1. Department of Psychiatry and Human Behavior, Center for Alcohol and Addiction Studies, Warren Alpert Medical School, Brown University, 121 South Main Street, Providence, RI 02912, USA. 2. Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, School of Public Health, Brown University, 121 South Main Street, Providence, RI 02912, USA. 3. Department of Cognitive, Linguistic and Psychological Sciences; Brown University, 121 South Main Street, Providence, RI 02912, USA.
Abstract
AIMS: Previous studies have shown that there may be an underlying mechanism that is common for co-use of alcohol and tobacco and it has been shown that treatment for alcohol use disorder can increase rates of smoking cessation. The primary aim of this study was to assess a novel methodological approach to test a simultaneous behavioral alcohol-smoking cue reactivity (CR) paradigm in people who drink alcohol and smoke cigarettes. METHODS: This was a human laboratory study that utilized a novel laboratory procedure with individuals who drink heavily (≥15 drinks/week for men; ≥8 drinks/week for women) and smoke (>5 cigarettes/day). Participants completed a CR in a bar laboratory and an eye-tracking (ET) session using their preferred alcohol beverage, cigarettes brand and water. RESULTS: In both the CR and ET session, there was a difference in time spent interacting with alcohol and cigarettes as compared to water (P's < 0.001), but no difference in time spent interacting between alcohol and cigarettes (P > 0.05). In the CR sessions, craving for cigarettes was significantly greater than craving for alcohol (P < 0.001), however, only time spent with alcohol, but not with cigarettes, was correlated with craving for both alcohol and cigarettes (P < 0.05). CONCLUSION: This study showed that it is feasible to use simultaneous cues during a CR procedure in a bar laboratory paradigm. The attention bias measured in the integrated alcohol-cigarettes ET procedure predicted participants' decision making in the CR. This novel methodological approach revealed that in people who drink heavily and smoke, alcohol cues may affect craving for both alcohol and cigarettes.
AIMS: Previous studies have shown that there may be an underlying mechanism that is common for co-use of alcohol and tobacco and it has been shown that treatment for alcohol use disorder can increase rates of smoking cessation. The primary aim of this study was to assess a novel methodological approach to test a simultaneous behavioral alcohol-smoking cue reactivity (CR) paradigm in people who drink alcohol and smoke cigarettes. METHODS: This was a human laboratory study that utilized a novel laboratory procedure with individuals who drink heavily (≥15 drinks/week for men; ≥8 drinks/week for women) and smoke (>5 cigarettes/day). Participants completed a CR in a bar laboratory and an eye-tracking (ET) session using their preferred alcohol beverage, cigarettes brand and water. RESULTS: In both the CR and ET session, there was a difference in time spent interacting with alcohol and cigarettes as compared to water (P's < 0.001), but no difference in time spent interacting between alcohol and cigarettes (P > 0.05). In the CR sessions, craving for cigarettes was significantly greater than craving for alcohol (P < 0.001), however, only time spent with alcohol, but not with cigarettes, was correlated with craving for both alcohol and cigarettes (P < 0.05). CONCLUSION: This study showed that it is feasible to use simultaneous cues during a CR procedure in a bar laboratory paradigm. The attention bias measured in the integrated alcohol-cigarettes ET procedure predicted participants' decision making in the CR. This novel methodological approach revealed that in people who drink heavily and smoke, alcohol cues may affect craving for both alcohol and cigarettes.
Authors: Christopher W Kahler; Jane Metrik; Nichea S Spillane; Anne Day; Adam M Leventhal; Sherry A McKee; Jennifer W Tidey; John E McGeary; Valerie S Knopik; Damaris J Rohsenow Journal: Psychopharmacology (Berl) Date: 2014-05-25 Impact factor: 4.530
Authors: D J Rohsenow; P M Monti; S M Colby; S B Gulliver; A D Sirota; R S Niaura; D B Abrams Journal: Alcohol Clin Exp Res Date: 1997-02 Impact factor: 3.455
Authors: Stewart A Shankman; Carter J Funkhouser; Daniel N Klein; Joanne Davila; Debra Lerner; Danelle Hee Journal: Int J Methods Psychiatr Res Date: 2017-10-16 Impact factor: 4.035