Literature DB >> 32983607

Disease severity and quality of life in homebound people with advanced Parkinson disease: A pilot study.

Jori E Fleisher1, Meghan M Sweeney1, Sarah Oyler1, Talia Meisel1, Naomi Friede1, Alessandro Di Rocco1, Joshua Chodosh1.   

Abstract

BACKGROUND: As Parkinson disease (PD) progresses, symptoms increase, quality of life (QoL) declines, and individuals may become homebound, often losing access to neurologic care. We aimed to determine whether facilitating expert in-home care could improve our understanding of disease progression, treatment options, and unmet needs in this vulnerable population, and whether such a model could mitigate decline in QoL.
METHODS: Patients with PD meeting Medicare homebound criteria were eligible for quarterly interdisciplinary home visits over 12 months. Each visit entailed an evaluation by a movement disorders neurologist, social worker, and nurse, including history, examination, medication reconciliation, psychosocial evaluation, pharmacologic and nonpharmacologic management, and service referrals. Disease severity, as measured by the Unified Parkinson's Disease Rating Scale (UPDRS), and QoL using the Neuro-QoL were measured at visits 1 and 4.
RESULTS: Of 27 enrolled patients, 23 completed 4 visits, with high retention and high patient- and caregiver-reported satisfaction. The mean age at baseline was 80.9 years (SD 7.8) with a mean total UPDRS of 65.0 (SD 20.0). After one year of home visits, total UPDRS worsened by a mean of 11.8 points (p < 0.01) without a change in any of 8 QoL domains (p = 0.19-0.95).
CONCLUSIONS: Homebound individuals with advanced PD receiving interdisciplinary home visits experienced no significant decline in QoL over 1 year, despite disease progression. Our findings highlight the disease severity and impaired QoL of the advanced, homebound PD population, and the potential for novel approaches to foster continuity of care.
© 2019 American Academy of Neurology.

Entities:  

Year:  2020        PMID: 32983607      PMCID: PMC7508339          DOI: 10.1212/CPJ.0000000000000716

Source DB:  PubMed          Journal:  Neurol Clin Pract        ISSN: 2163-0402


  32 in total

1.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.

Authors:  M F Folstein; S E Folstein; P R McHugh
Journal:  J Psychiatr Res       Date:  1975-11       Impact factor: 4.791

2.  An interdisciplinary home healthcare program for patients with Parkinson's disease.

Authors:  L F Vickers; C M O'Neill
Journal:  Rehabil Nurs       Date:  1998 Nov-Dec       Impact factor: 1.625

3.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Authors:  Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde
Journal:  J Biomed Inform       Date:  2008-09-30       Impact factor: 6.317

4.  Guiding principles for the care of older adults with multimorbidity: an approach for clinicians: American Geriatrics Society Expert Panel on the Care of Older Adults with Multimorbidity.

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Journal:  J Am Geriatr Soc       Date:  2012-09-19       Impact factor: 5.562

5.  Associations and implications of low health literacy in Parkinson's Disease.

Authors:  Jori E Fleisher; Krunal Shah; Whitney Fitts; Nabila A Dahodwala
Journal:  Mov Disord Clin Pract       Date:  2015-12-14

6.  Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.

Authors:  A J Hughes; S E Daniel; L Kilford; A J Lees
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-03       Impact factor: 10.154

Review 7.  Successful models of comprehensive care for older adults with chronic conditions: evidence for the Institute of Medicine's "retooling for an aging America" report.

Authors:  Chad Boult; Ariel Frank Green; Lisa B Boult; James T Pacala; Claire Snyder; Bruce Leff
Journal:  J Am Geriatr Soc       Date:  2009-12       Impact factor: 5.562

8.  Caregiver strain in Parkinson's disease: national Parkinson Foundation Quality Initiative study.

Authors:  O Oguh; M Kwasny; J Carter; B Stell; T Simuni
Journal:  Parkinsonism Relat Disord       Date:  2013-07-18       Impact factor: 4.891

9.  Neuro-QOL: brief measures of health-related quality of life for clinical research in neurology.

Authors:  D Cella; J-S Lai; C J Nowinski; D Victorson; A Peterman; D Miller; F Bethoux; A Heinemann; S Rubin; J E Cavazos; A T Reder; R Sufit; T Simuni; G L Holmes; A Siderowf; V Wojna; R Bode; N McKinney; T Podrabsky; K Wortman; S Choi; R Gershon; N Rothrock; C Moy
Journal:  Neurology       Date:  2012-05-09       Impact factor: 9.910

10.  HD-PRO-TRIAD™ Validation: A Patient-reported Instrument for the Symptom Triad of Huntington's Disease.

Authors:  Noelle E Carlozzi; David Victorson; Victor Sung; Jennifer L Beaumont; Wendy Cheng; Brian Gorin; Mei Sheng Duh; David Samuelson; David Tulsky; Sandra Gutierrez; Cindy J Nowinski; Allison Mueller; Vivienne Shen; Samuel Frank
Journal:  Tremor Other Hyperkinet Mov (N Y)       Date:  2014-04-14
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  7 in total

1.  The Role of Parkinson Nurses for Personalizing Care in Parkinson's Disease: A Systematic Review and Meta-Analysis.

Authors:  Marlena van Munster; Johanne Stümpel; Franziska Thieken; Florin Ratajczak; Olivier Rascol; Margherita Fabbri; Timo Clemens; Katarzyna Czabanowska; Tiago A Mestre; David J Pedrosa
Journal:  J Parkinsons Dis       Date:  2022       Impact factor: 5.520

2.  IN-HOME-PD: The effects of longitudinal telehealth-enhanced interdisciplinary home visits on care and quality of life for homebound individuals with Parkinson's disease.

Authors:  Jori E Fleisher; Serena P Hess; Ellen C Klostermann; Jeanette Lee; Erica Myrick; Daniela Mitchem; Claire Niemet; Katheryn Woo; Brianna J Sennott; Maya Sanghvi; Natalie Witek; James C Beck; Jayne R Wilkinson; Bichun Ouyang; Deborah A Hall; Joshua Chodosh
Journal:  Parkinsonism Relat Disord       Date:  2022-08-07       Impact factor: 4.402

3.  The impact and feasibility of a brief, virtual, educational intervention for home healthcare professionals on Parkinson's Disease and Related Disorders: pilot study of I SEE PD Home.

Authors:  Serena P Hess; Melissa Levin; Faizan Akram; Katheryn Woo; Lauren Andersen; Kristie Trenkle; Patricia Brown; Bichun Ouyang; Jori E Fleisher
Journal:  BMC Med Educ       Date:  2022-06-28       Impact factor: 3.263

Review 4.  Personalized Care in Late-Stage Parkinson's Disease: Challenges and Opportunities.

Authors:  Margherita Fabbri; Miguel Coelho; Michela Garon; Roberta Biundo; Tiago A Mestre; Angelo Antonini
Journal:  J Pers Med       Date:  2022-05-18

5.  Novel Outreach Program and Practical Strategies for Patients with Parkinsonism in the COVID-19 Pandemic.

Authors:  Brianna Sennott; Katheryn Woo; Serena Hess; Daniela Mitchem; Ellen C Klostermann; Erica Myrick; Rodolfo Savica; Jori E Fleisher
Journal:  J Parkinsons Dis       Date:  2020       Impact factor: 5.568

6.  Peer Mentoring Program for Informal Caregivers of Homebound Individuals With Advanced Parkinson Disease (Share the Care): Protocol for a Single-Center, Crossover Pilot Study.

Authors:  Jori E Fleisher; Faizan Akram; Jeanette Lee; Ellen C Klostermann; Serena P Hess; Erica Myrick; Melissa Levin; Bichun Ouyang; Jayne Wilkinson; Deborah A Hall; Joshua Chodosh
Journal:  JMIR Res Protoc       Date:  2022-05-26

7.  Longitudinal, Interdisciplinary Home Visits Versus Usual Care for Homebound People With Advanced Parkinson Disease: Protocol for a Controlled Trial.

Authors:  Jori E Fleisher; Serena Hess; Brianna J Sennott; Erica Myrick; Ellen Klostermann Wallace; Jeanette Lee; Maya Sanghvi; Katheryn Woo; Bichun Ouyang; Jayne R Wilkinson; James Beck; Tricia J Johnson; Deborah A Hall; Joshua Chodosh
Journal:  JMIR Res Protoc       Date:  2021-09-14
  7 in total

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