Literature DB >> 32980139

Smart implants in fracture care - only buzzword or real opportunity?

Manuela Ernst1, R Geoff Richards2, Markus Windolf3.   

Abstract

The assessment of fracture healing is still marked by a subjective and diffuse outcome due to the lack of clinically available quantitative measures. Without reliable information on the progression of healing and uniform criteria for union and non-union, therapeutic decision making, e.g. regarding the allowed weight bearing, hinges on the experience and the subjective evaluation of physicians. Already decades ago, fracture stiffness has been identified as a valid outcome measure for the maturity of the repair tissue. Despite early promising results, so far no method has made its way into practice beyond clinical studies. However, with current technological advancements and a general trend towards digital health care, measuring fracture healing seems to regain momentum. New generations of instrumented implants with sensoring capabilities, often termed as "smart implants", are under development. They target X-ray free and timely provision of reliable feedback upon the mechanical competence of the repair tissue and the healing environment to support therapeutic decision making and individualized after-care. With the gained experience from these devices, the next generations of smart implants may become increasingly sophisticated by internally analyzing the measured data and suggesting adequate therapeutic actions on their own.
Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Fracture healing; Monitoring; Smart implants

Year:  2020        PMID: 32980139     DOI: 10.1016/j.injury.2020.09.026

Source DB:  PubMed          Journal:  Injury        ISSN: 0020-1383            Impact factor:   2.586


  6 in total

Review 1.  Implantable biosensors for musculoskeletal health.

Authors:  Kylie E Nash; Keat Ghee Ong; Robert E Guldberg
Journal:  Connect Tissue Res       Date:  2022-02-17       Impact factor: 3.417

2.  Programable Active Fixator System for Systematic In Vivo Investigation of Bone Healing Processes.

Authors:  Jan Barcik; Manuela Ernst; Constantin E Dlaska; Ludmil Drenchev; Stephan Zeiter; Devakara R Epari; Markus Windolf
Journal:  Sensors (Basel)       Date:  2020-12-22       Impact factor: 3.576

3.  Continuous Implant Load Monitoring to Assess Bone Healing Status-Evidence from Animal Testing.

Authors:  Markus Windolf; Viktor Varjas; Dominic Gehweiler; Ronald Schwyn; Daniel Arens; Caroline Constant; Stephan Zeiter; Robert Geoff Richards; Manuela Ernst
Journal:  Medicina (Kaunas)       Date:  2022-06-27       Impact factor: 2.948

4.  Continuous Rod Load Monitoring to Assess Spinal Fusion Status-Pilot In Vivo Data in Sheep.

Authors:  Markus Windolf; Maximilian Heumann; Viktor Varjas; Caroline Constant; Manuela Ernst; Robert Geoff Richards; Hans-Joachim Wilke; Lorin Michael Benneker
Journal:  Medicina (Kaunas)       Date:  2022-07-06       Impact factor: 2.948

5.  Non-destructive characterization of bone mineral content by machine learning-assisted electrochemical impedance spectroscopy.

Authors:  Aihik Banerjee; Youyi Tai; Nosang V Myung; Jin Nam
Journal:  Front Bioeng Biotechnol       Date:  2022-09-05

Review 6.  Finite Element Analysis of Fracture Fixation.

Authors:  Gregory S Lewis; Dominic Mischler; Hwabok Wee; J Spence Reid; Peter Varga
Journal:  Curr Osteoporos Rep       Date:  2021-06-29       Impact factor: 5.163

  6 in total

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