Farrokh Heidari1, Firouzeh Heidari1, Benyamin Rahmaty2, Neda Jafari3, Kayvan Aghazadeh4, Saeed Sohrabpour1, Ebrahim Karimi5. 1. Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran. 2. Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: B-rahmaty@razi.tums.ac.ir. 3. Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran. 4. Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: aghazadeh@sina.tums.ac.ir. 5. Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: karimient@gmail.com.
Abstract
OBJECTIVES: Usefulness of preoperative tissue sampling and pathology diagnoses in parotid gland tumors were accepted worldwide. We investigate the role of CNB in the parotid gland lesions when FNA results are inconclusive. METHODS: We conducted a cross sectional study to evaluate CNB results from fifty-two patients with history of parotid gland lesion and inconclusive previous fine needle aspiration. RESULTS: In this study, 45 out of 52 CNB results determined definite histological subtype diagnosis. Four CNB reports were inconclusive and three CNB results were compatible with malignancies, but did not define definite diagnosis. Calculated sensitivity for diagnosis of malignancy was 96% and specificity was 85%. Negative predictive value, positive predictive value, and accuracy for CNB in detecting malignancy, were calculated 94%, 90%, and 92%, respectively. CONCLUSIONS: When FNA is not conclusive, CNB may be used as a precise method to evaluate the parotid gland lesions.
OBJECTIVES: Usefulness of preoperative tissue sampling and pathology diagnoses in parotid gland tumors were accepted worldwide. We investigate the role of CNB in the parotid gland lesions when FNA results are inconclusive. METHODS: We conducted a cross sectional study to evaluate CNB results from fifty-two patients with history of parotid gland lesion and inconclusive previous fine needle aspiration. RESULTS: In this study, 45 out of 52 CNB results determined definite histological subtype diagnosis. Four CNB reports were inconclusive and three CNB results were compatible with malignancies, but did not define definite diagnosis. Calculated sensitivity for diagnosis of malignancy was 96% and specificity was 85%. Negative predictive value, positive predictive value, and accuracy for CNB in detecting malignancy, were calculated 94%, 90%, and 92%, respectively. CONCLUSIONS: When FNA is not conclusive, CNB may be used as a precise method to evaluate the parotid gland lesions.
Authors: Katharine Julia Hurry; Dilhara Karunaratne; Suzanne Westley; Alessandra Booth; Keith C R B Ramesar; Ting Ting Zhang; Michael Williams; David C Howlett Journal: Br J Radiol Date: 2021-12-03 Impact factor: 3.039