| Literature DB >> 32971000 |
Horia Pribiag1, Byung Kook Lim2.
Abstract
Opioids are commonly used as analgesics for severe pain, but their addictive potential has sparked a misuse epidemic. In this issue of Neuron, Keyes et al. (2020) examine the contributions of distinct paraventricular thalamus (PVT) outputs to contextual opioid memories. They identify a PVT→NAc→LH circuit essential for recall of opioid experiences. Published by Elsevier Inc.Entities:
Keywords: brain-wide c-Fos; central amygdala; chemogenetics; drug-related memory; lateral hypothalamus; morphine; nucleus accumbens; opioids; optogenetics; paraventricular thalamus
Mesh:
Substances:
Year: 2020 PMID: 32971000 PMCID: PMC8916046 DOI: 10.1016/j.neuron.2020.09.006
Source DB: PubMed Journal: Neuron ISSN: 0896-6273 Impact factor: 17.173